- ￥1050 - 2300
- 泽叶生物
- ZY909200
- 中国
- 2025年07月10日
- 见说明书
- 小鼠
- Human, Mouse, Rattus Other species not tested.
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- 详细信息
- 文献和实验
- 技术资料
- 供应商：
上海泽叶生物科技有限公司
- 库存：
100
- 靶点：
见说明书
- 级别：
高
- 目录编号：
ZY909200
- 克隆性：
多克隆
- 抗原来源：
多抗制备
- 保质期：
2年
- 抗体英文名：
HMGB1
- 抗体名：
HMGB1
- 标记物：
无标记物
- 宿主：
小鼠
- 适应物种：
Human, Mouse, Rattus Other species not tested.
- 免疫原：
详见说明书
- 亚型：
Ig亚型IgG
- 形态：
液体或冻干粉
- 应用范围：
见说明书
- 保存条件：
-20°C
- 浓度：
0.5mg/ml
- 规格：
50ul/100ul/200ul
| 规格： | 50ul | 产品价格： | ￥1050.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1500.0 |
| 规格： | 200ul | 产品价格： | ￥2300.0 |
| Catalog No | ZY909200 |
|---|---|
| Species Reactivity | Human, Mouse, Rattus Other species not tested. |
| Immunogen | A peptide corresponding to middle region of human HMGB1 protein. |
| GeneBank No. | NM_002128 |
| Alternative Names | HMG-1; HMG1; HMG3; SBP-1 |
| Purification | Purified by protein A/G column. |
| Isotype | IgG |
| Formulation | Lyophilized power with 0.02% NaN3. Or dissolved in sterile H2O with 50% glycerol. |
| Applications | |
|---|---|
| ELISA | 1:20,000-1:80,000 |
| Western blot | 1:200-1:1,000 |
| For research use only. Optimal dilutions/concentrations should be determined by the final use. | |
| DATA | ||
|---|---|---|
|
||
| Observed Molecular Weight | 40kd | |
| PREPARATION AND STORAGE | |
|---|---|
| Reconstitution | If lyophilized, reconstitute in indicated volume of sterile H2O. For extended storage, we suggest the addition of an equal volume of glycerol to make a final glycerol concentration of 50%. |
| Storage | Shipped at ambient temperature or with ice bags if in liquid. Store immediately at-20°C upon receipt. Avoid repeating freeze-thaw cycles. |
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文献和实验Fluorescent Biosensors for the Detection of HMGB1 Release
During necrosis and following some instances of apoptosis (in particular in the absence of a proficient phagocytic system), the nonhistone chromatin component high-mobility group box 1 (HMGB1) is released in the extracellular space. In vivo
因为journal club要讲文章 顺便儿拿来和大家讨论下 Hmgb1调节TLR4介导的angiogenesis 最近才开始关注这个蛋白。这篇文章已经在线发表在atvb上，由中山医眼科中心完成的工作。 Hmgb1不仅可以作为一种nuclear factor, 而且还可以作为cytokine来介导感染引起的炎症，免疫损伤。Hmgb1已经在sepsis, arthritis, 肿瘤和其他多种疾病中明确了其作用。Hmgb1可以结合tlr2/4，并且通过MyD88依赖性信号通路促进
Generation of Antibody Molecules Through Antibody Engineering
been overcome to a large extent using genetic-engineering techniques to produce chimeric mouse/human and completely human antibodies. Such an approach is particularly suitable because of the domain structure of the antibody molecule ( 2 ), where functional
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