相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 库存:
999
- 英文名:
L-Proline
- CAS号:
147-85-3
- 保质期:
详见产品说明
- 供应商:
仕诺达生物
- 保存条件:
2-8°C
- 规格:
200mg;分析标准品98%(多规格可选)/1g;分析标准品98%/10g;BR 99%/25g;BR 99%
| 规格: | 200mg;分析标准品98%(多规格可选) | 产品价格: | ¥65.0 |
|---|---|---|---|
| 规格: | 1g;分析标准品98% | 产品价格: | ¥100.0 |
| 规格: | 10g;BR 99% | 产品价格: | ¥25.0 |
| 规格: | 25g;BR 99% | 产品价格: | ¥40.0 |

性质
- 本品为针状结晶或斜方结晶。有强甜味,几乎无臭。熔点222℃(分解)。极易溶于水(162. 3%,25℃),溶于乙醇,不溶于醚和丁醇,易潮解,不易得到结晶。
- 它是含吡烷的亚氨基酸,属非必需氨基酸之一。在生物体内,从谷氨酸出发经△' 吡啉-5-羧酸合成得,分解则通过与生物合成的逆反应相同的过程转向谷氨酸代谢。在骨胶原等蛋白质中,氨酸残基以羟基化形式(羟脯氨酸)存在。
| 中文名 | L-脯氨酸 |
| 英文名 | L(-)-Proline |
| 别名 | 脯氨酸 L-脯氨酸 依那普利杂质8 (S)-吡烷-2-羧酸 L-PROLINE L-脯氨酸 脯氨酸 (PRO)溶液,100PPM |
| 英文别名 | Proline H-Pro-OH L-Proline L(-)-Proline L(-)-Proline 0 L-PROLINE, NATURAL L-PROLINE, SYNTHETIC 2-Pyrrolidinecarboxylic acid L-(-)-PROLINE ((S)-(-)-PROLINE) (S)-Pyrrolidine-2-carboxylic acid L-Proline ,L-2-Pyrrolidinecarboxylic acid |
| CAS | 147-85-3 |
| EINECS | 205-702-2 |
| 化学式 | CH9NO2 |
| 分子量 | 115.13 |
| InChI | InChI=1/CH9NO2/c7-5(8)4-2-1-3-6-4/h4,6H,1-3H2,(H,7,8)/t4-/m1/s1 |
| InChIKey | ONIBWKKTOPOVIA-UHFFFAOYSA-N |
| 密度 | 1.35 |
| 熔点 | 228 °C (dec.) (lit.) |
| 沸点 | 215.41°C (rough estimate) |
| 比旋光度 | -85.5 º (c=4, H2O) |
| 闪点 | 106.3°C |
| 水溶性 | soluble |
| 蒸汽压 | 0Pa at 25℃ |
| JECFA Number | 1425 |
| 溶解度 | H2O: 50 mg/mL |
| 折射率 | -85 ° (C=4, H2O) |
| 酸度系数 | 1.95, 10.64(at 25℃) |
| PH值 | 6.0-7.0 (25℃, 1M in H2O) |
| 存储条件 | 2-8°C |
| 稳定性 | 稳定。与强氧化剂不相容。 |
| 敏感性 | Hygroscopic |
| 外观 | 粉末 |
| 颜色 | White |
| 最大波长(λmax) | ['λ: 260 nm Amax: 0.05', , 'λ: 280 nm Amax: 0.05'] |
| Merck | 14,7780 |
| BRN | 80810 |
| 物化性质 | 无色结晶,无臭,味甜;易溶于水(25℃水中溶解度为162.3 g/100 ml)和乙醇,不溶于丁醇,遇水合茚三酮试液呈黄色,冰乙酸酸化后显红色;pI6.3,分解点为220-222℃;比旋光度[α]20D-85°(0.5-2.0 mg/ml,H2O),[α]20D-60.4°(0.5-2.0 mg/ml,5 mol/L HCl)。 |
计算化学数据:
- 分子量:115.13g/mol
- 化合物是否规范:True
- 准确质量:115.063328530
- 同位素质量:115.063328530
- 复杂度:103
- 可旋转化学键数量:1
- 氢键供体数量:2
- 氢键受体计数:3
- 拓扑极表面积:49.3
- 重原子数量:8
- 确定原子立构中心数量:1
- 不确定原子立构中心数量:0
- 确定化学键立构中心数量:0
- 不确定化学键立构中心数量:0
- 同位素原子计数:0
- 共价键单元数量:1
- CACTVS Substructure Key Fingerprint:AAADccBiMAAAAAAAAAAAAAAAAAAAAWAAAAAAAAAAAAAAAAAAAAAAHgAQCAAACCjBgAQACALAAgAIAACQCAAAAAAAAAAAAIGIAAACABIAgCAEQAAEEACQAACYEQAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA==

■针对客户购买情况公司有不同的优惠折扣,欢迎咨询订购~
■郑重申明:本公司销售所有产品均为实物拍摄,如产品出现质量问题,本公司包一切售后!!!
■500元以上包邮,本公司提供正规发票,货到付款,可按科研实验要求定制产品!!!
■本公司已与很多高校中科院及研发单位合作并也获得了老师的认可和推荐!!!
风险提示:丁香通仅作为第三方平台,为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全,合理判断,谨慎选购商品,商家和用户对交易行为负责。对于医疗器械类产品,请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验1. 甘惠玉 黄露. L-脯氨酸修饰金纳米通道的制备及应用[J]. 闽江学院学报 2019 40(02):101-105.
2. 宫瑞泽 赵卉 曲迪 等. 不同产地加工及炮制方法对鹿茸中胶原蛋白含量的影响[J]. 食品科学 2019(22).
3. 侯丽娟 严超 齐晓茹 王颉. 不同品种红枣酿制枣酒的香气差异性研究[J]. 食品工业 2017(5):208-212.
4. 甘学文,王光耀,邓仕彬,张春晖,崔和平,刘曙光,于静洋,成涛,张晓鸣.美拉德反应中间体对卷烟评吸品质的影响及其风味受控形成研究[J].食品与机械,2017,33(06):46-52.
5. 刘丹宁, 黄洁瑶, 杨璐嘉,等. 超声波辅助低共熔溶剂提取枳实中芸香柚皮苷,柚皮苷和橙皮苷[J]. 中药材 2020年43卷1期, 155-160页, MEDLINE ISTIC PKU, 2020.
6. 谈梦霞, 陈佳丽, 邹立思,等. 不同贮藏条件对麦冬药材质量的影响[J]. 中药材, 2018(11).
7. 王婷婷,郜玉钢,臧埔,赵岩,何忠梅,祝洪艳,张连学.复方麦鹿芪人参制剂主要成分变化及其在肝癌H22荷瘤小鼠体内的抗肿瘤作用[J].吉林大学学报(医学版),2017,43(04):698-704+858-859.
8. 李婉斯, 李婷, 陆春怡,等. 基于HPLC指纹图谱及聚类分析评价市售阿胶的质量[J]. 上海中医药大学学报, 2017, 031(006):91-96.
9. 马长中, 罗章, 辜雪冬. 林芝砖红绒盖牛肝菌的营养成分分析及评价[J]. 食品科学, 2016, 37(024):124-129.
10. 陈思, 郜玉钢, 臧埔,等. 鹿角脱盘及其5种提取部位21种氨基酸含量对比分析[J]. 药物分析杂志, 2017(10):1851-1857.
11. 谈梦霞, 陈佳丽, 邹立思,等. 麦冬与山麦冬中多元指标成分的比较分析[J]. 中国中药杂志, 2018, 43(20).
12. 祝洪艳, 张荻, 张力娜,等. 柱前衍生化HPLC法检测紫苏子和紫苏叶中氨基酸的含量[J]. 药物分析杂志, 2017(10):1858-1864.
13. 唐何娜, 杨磊, 欧阳志远,等. 基于体外仿生的海水珍珠矿化机制初步研究[J]. 电子显微学报, 2017, 036(006):589-597.
14. 严超, 侯丽娟, 齐晓茹,等. 红枣白兰地发酵过程中酒醅氨基酸和有机酸的变化分析[J]. 食品工业科技, 2017, 38(014):121-125.
15. 姜鹏, 孙言才, 蔡颖,等. 基于超高效液相色谱-高分辨质谱联用技术研究苦参醇提物致大鼠肝毒性的尿液代谢组[J]. 安徽中医药大学学报, 2018.
16. Wang, Chengcheng, et al. "Distribution patterns for metabolites in medicinal parts of wild and cultivated licorice." Journal of pharmaceutical and biomedical analysis 161 (2018): 464-473.
17. Weifeng Chen, Guo Lv, Xiang Liu, Jiaying Yan, Qichun Zhang, Dong-Sheng Li,A universal high-efficient and reusable “on–off” switch for the on-demand hydrogen evolution,Chemical Engineering Journal Advances,Volume 7,2021,100128,ISSN 2666-8211,
18. Ji, Youan, et al. "Highly efficient separation of indole from model wash oil using tetraethyl ammonium amino acid ionic liquids." Separation and Purification Technology 258 (2021): 117997.
19. Xinru Xu, Mingguang Yu, Junaid Raza, Huanlu Song, Lin Gong, Wenqing Pan, Study of the mechanism of flavor compounds formed via taste-active peptides in bovine bone protein extract, LWT, Volume 137, 2021, 110371, ISSN 0023-6438,
20. Qu, Fengfeng, et al. "Effect of different drying methods on the sensory quality and chemical components of black tea." Lwt 99 (2019): 112-118
21. Li, Suhong, et al. "Mechanisms of high concentration valine-mediated inhibition of peach tree shoot growth." Frontiers in Plant Science 11 (2020).
22. Cai, Z, Liao, H, Wang, C, et al. A comprehensive study of the aerial parts of Lonicera japonica Thunb. based on metabolite profiling coupled with PLS-DA. Phytochemical Analysis. 2020; 31: 786– 800.
23. Zhao, Zheng, et al. "Cholinium amino acids-glycerol mixtures: New class of solvents for pretreating wheat straw to facilitate enzymatic hydrolysis." Bioresource technology 245 (2017): 625-632.
24. Jiang, Peng, Yancai Sun, and Nengneng Cheng. "Liver metabolomic characterization of Sophora flavescens alcohol extract-induced hepatotoxicity in rats through UPLC/LTQ-Orbitrap mass spectrometry." Xenobiotica 50.6 (2020): 670-676.
25. [IF=6.079] Tian Luo et al."Determination of underivatized amino acids to evaluate quality of beer by capillary electrophoresis with online sweeping technique."J Food Drug Anal. 2017 Oct;25:789
26. [IF=5.923] Cuihua Chen et al."Variations in Physiology and Multiple Bioactive Constituents under Salt Stress Provide Insight into the Quality Evaluation of Apocyni Veneti Folium."Int J Mol Sci. 2018 Oct;19(10):3042
27. [IF=4.952] Fengfeng Qu et al."Effect of different drying methods on the sensory quality and chemical components of black tea."Lwt Food Sci Technol. 2019 Jan;99:112
28. [IF=4.411] Yujiao Hua et al."Quality Evaluation of Pseudostellariae Radix Based on Simultaneous Determination of Multiple Bioactive Components Combined with Grey Relational Analysis."Molecules. 2017 Jan;22(1):13
29. [IF=3.535] Tian Luo et al."Establishing a sensitive capillary electrophoresis-UV method for direct determination of amino acids to evaluate vinegar quality."Electrophoresis. 2018 Jun;39(11):1410-1416
30. [IF=2.896] Jing Ke et al."Development of a gradient micellar liquid chromatographic method eluting from micellar mode to high submicellar mode for the rapid separation of free amino acids."Anal Methods-Uk. 2017 Mar;9(11):1762-1770
31. [IF=2.896] Ya-yun Chen et al."Determination of free amino acids and nucleosides and nucleobases in Annona squamosa L. fruitages from different regions in China by LC-QTRAP-MS/MS."Anal Methods-Uk. 2017 Jun;9(25):3862-3869
32. [IF=2.727] Tian Luo et al."Quality assessment of soy sauce using underivatized amino acids by capillary electrophoresis."International Journal Of Food Properties. 2018 Jan 08
33. [IF=1.913] Xie Yunfei et al."Rapid Determination of Amino Acids in Beer, Red Wine, and Donkey-Hide Gelatin by Gradient Elution of HPLC: From Micellar Liquid Chromatography to High Submicellar Liquid Chromatography."J Aoac Int. 2018 Jan;101(1):249-255
34. [IF=13.273] Xiaoxiao Wei et al."Fabrication of di-selective adsorption platform based on deep eutectic solvent stabilized magnetic polydopamine: Achieving di-selectivity conversion through adding CaCl2."Chem Eng J. 2021 Oct;421:127815
35. [IF=7.79] Ye Lu et al."Enhancing hydrogel-based long-lasting chemiluminescence by a platinum-metal organic framework and its application in array detection of pesticides and D-amino acids."Nanoscale. 2020 Feb;12(8):4959-4967
36. [IF=7.514] Yayuan Tang et al."Comprehensive evaluation on tailor-made deep eutectic solvents (DESs) in extracting tea saponins from seed pomace of Camellia oleifera Abel."Food Chem. 2021 Apr;342:128243
37. [IF=6.475] Yuran Wang et al."Proline-glucose Amadori compounds: Aqueous preparation, characterization and saltiness enhancement."Food Res Int. 2021 Jun;144:110319
38. [IF=5.833] Chen Jing et al."A composite prepared from MnO2 nanosheets and a deep eutectic solvent as an oxidase mimic for the colorimetric determination of DNA."Microchim Acta. 2020 Jan;187(1):1-7
39. [IF=5.753] Suhong Li et al."Mechanisms of High Concentration Valine-Mediated Inhibition of Peach Tree Shoot Growth."Front Plant Sci. 2020; 11: 603067
40. [IF=5.537] Yurong Ma et al."Pre-cut NaCl solution treatment effectively inhibited the browning of fresh-cut potato by influencing polyphenol oxidase activity and several free amino acids contents."Postharvest Biol Tec. 2021 Aug;178:111543
41. [IF=4.952] Xinru Xu et al."Study of the mechanism of flavor compounds formed via taste-active peptides in bovine bone protein extract."Lwt Food Sci Technol. 2021 Feb;137:110371
42. [IF=4.952] Huan Zhang et al."Label-free quantification proteomics reveals the active peptides from protein degradation during anaerobic fermentation of tea."Lwt Food Sci Technol. 2021 Oct;150:111950
43. [IF=4.821] Peng Wan et al."Analysis of aroma-active compounds in bighead carp head soup and their influence on umami of a model soup."Microchem J. 2021 Sep;168:106436
44. [IF=4.616] Ling Li et al."Point-of-care testing of melamine via gas pressure readout using polythymine-coated Au@Pt nanoparticles through specific triple hydrogen-bonding recognition."Analyst. 2021 Sep;146(19):5898-5903
45. [IF=4.556] Dandan Zhao et al."Physico-chemical properties and free amino acids profiles of six wolfberry cultivars in Zhongning."J Food Compos Anal. 2020 May;88:103460
46. [IF=4.466] Yao Tan et al."Multiomics Integrative Analysis for Discovering the Potential Mechanism of Dioscin against Hyperuricemia Mice."J Proteome Res. 2021;20(1):645–660
47. [IF=4.411] Mengxia Tan et al."Quality Evaluation of Ophiopogonis Radix from Two Different Producing Areas."Molecules. 2019 Jan;24(18):3220
48. [IF=4.411] Shengxin Yin et al."Comparison of Multiple Bioactive Constituents in the Corolla and Other Parts of Abelmoschus manihot."Molecules. 2021 Jan;26(7):1864
49. [IF=4.379] Feng Lin et al."Chemical profile changes during pile fermentation of Qingzhuan tea affect inhibition of α-amylase and lipase."Sci Rep-Uk. 2020 Feb;10(1):1-10
50. [IF=4.35] Xiaomei Dai et al."1-Methylcyclopropene Preserves the Quality of Chive (Allium schoenoprasum L.) by Enhancing Its Antioxidant Capacities and Organosulfur Profile during Storage."Foods. 2021 Aug;10(8):1792
51. [IF=4.27] Cuihua Chen et al."Metabolomics characterizes metabolic changes of Apocyni Veneti Folium in response to salt stress."Plant Physiol Bioch. 2019 Nov;144:187
52. [IF=4.142] Wang Chenxi et al."Systematic quality evaluation of Peiyuan Tongnao capsule by offline two-dimensional liquid chromatography/quadrupole-Orbitrap mass spectrometry and adjusted parallel reaction monitoring of quality markers."Anal Bioanal Chem. 2019 Nov;4
53. [IF=3.935] Biru Shi et al."Investigation on the stability in plant metabolomics with a special focus on freeze-thaw cycles: LC–MS and NMR analysis to Cassiae Semen (Cassia obtusifolia L.) seeds as a case study."J Pharmaceut Biomed. 2021 Sep;204:114243
54. [IF=3.373] Zhichen Cai et al."A comprehensive study of the aerial parts of Lonicera japonica Thunb. based on metabolite profiling coupled with PLS-DA."Phytochem Analysis. 2020 Nov;31(6):786-800
55. [IF=3.373] Wanning Chen et al."The composition differences between small black beans and big black beans from different habitats and its effects on the processing of Polygonum multiflorum."Phytochem Analysis. 2021 Sep;32(5):767-779
56. [IF=3.361] Ruixue Yu et al."Targeted neurotransmitter metabolomics profiling of oleanolic acid in the treatment of spontaneously hypertensive rats."Rsc Adv. 2019 Jul;9(40):23276-23288
57. [IF=3.24] Zhichen Cai et al."Metabolomics characterizes the metabolic changes of Lonicerae Japonicae Flos under different salt stresses."Plos One. 2020 Dec;15(12):e0243111
58. [IF=2.097] Ke Jing et al."Isocratic micellar liquid chromatography using mixed anionic and non-ionic surfactants as mobile phase additives for separation of 17 free amino acids."Chem Pap. 2019 Oct;73(10):2417-2426
玉米Proline responding 1(pro1)突变在蛋白合成和细胞周期调控中起到关键作用
(Figure 1E,F,J)。此外,pro1突变体其幼苗一般在发育到两叶期时生长受到严重抑制,继而发生坏死导致死亡。在加入外源L-脯氨酸的培养基上进行培养时,突变体幼苗可以回复到野生型表型,越过两叶期继续生长。因此,研究人员将这个新发现的突变体命名为Pro1突变。Figure 1 Phenotypic Features of Maize prol1 Mutants.(A)F2 ear of pro1-ref×Chang 7-2. bar: 1cm.(B)Wild type and mutant
) DL- 半胱氨酸 DL-cystinge(Cyss) 240.29 260 0.0049 5.05 (1)1.65(2)2.26 (3)7.85(4)9.85 L- 胱氨酸 L-cystinge(Cyss) 240.29 258-261d 0.011 5.05 DL- 谷氨酸 DL-glutamic acid(Glu) 147.13 225-227d
谷氨酸 2.5克 4.2克 5.7克 甘 氨 酸 3.5克 5.9克 7.9克 L-组氨酸 3.0克 5.0克 6.8克 L-异亮氨酸 2.5克 4.2克 5.7克 L-亮氨酸 3.4克 5.9克 7.9克 L-醋酸赖氨酸 5.5克 9.5克 12.7克 L-蛋氨酸 2.5克 4.2克 5.7克 L-苯丙氨酸 3.5克 5.9克 7.9克 L-脯氨酸 2.9克 5.0克 6.8克 L-丝氨酸 1.9克 3.4克 4.5克 L-苏氨酸 2.5克 4.2克 5.7克 L-色氨酸 0.85克 1.4克 1.9克











