SET SALICAP SLV. 500SETS

Association Analysis for Large-Scale Gene Set Data

sets, and for creating working hypotheses, which can be tested experimentally. One obvious way to analyze gene set data is to associate the genes with a particular biological feature, for example, a given pathway. Statistical analysis could be used

Off-Target Networks Derived from Ligand Set Similarity

, when drugs may bind them in defiance of bioinformatic criteria? Here we consider a technique that quantitatively relates proteins based on the chemical similarity of their ligands. Starting with tens of thousands of ligands organized into sets for hundreds

Visualizing Gene-Set Enrichment Results Using the Cytoscape Plug-in Enrichment Map

Gene-set enrichment analysis finds functionally coherent gene-sets, such as pathways, that are statistically overrepresented in a given gene list. Ideally, the number of resulting sets is smaller than the number of genes in the list