Obestatin (mouse, rat) EIA Kit

甘丙肽（Obestatin）是一种由23个氨基酸组成的酰胺化肽，具有α螺旋二级结构。它于2005年首次从大鼠胃中分离出来。甘丙肽是一种由前胃饥饿素（preproghrelin）衍生而来的肽，可由胃、胰腺、脂肪组织、骨骼肌和心脏等多种组织或器官产生。甘丙肽最初被认为是一种厌食性肽，通过对抗胃饥饿素的作用来减少食物摄入和体重。它还被认为是一种抗糖尿病肽，能够积极调节葡萄糖和脂质代谢。此外，甘丙肽可能在血压调节中发挥作用，因为其血浆浓度在高血压患者中有所增加。甘丙肽还可能参与调节焦虑情绪并改善记忆功能。Obestatin is an amidated peptide of 23 amino acids with an α-helical secondary conformation. It was first isolated from rat stomach in 2005. Obestatin is a preproghrelin-derived peptide produced by many tissues or organs, including the stomach, pancreas, adipose tissue, skeletal muscle, and the heart. Obestatin was originally identified as an anorexigenic peptide that reduces food intake and body weight by opposing the actions of ghrelin. It has been considered to be an antidiabetic peptide that positively influences glucose and lipid metabolism. It may also play a role in the regulation of blood pressure as its plasma concentration increases in hypertensive patients. Obestatin may also have a role in the regulation of anxiety and memory improvement.