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文献和实验towards degradation by exo- and endonucleases in serum and in tissue homogenates. The conjugation of cholesterol to the 3' end of the sense strand of a siRNA molecule by means of a pyrrolidine linker (thereby generating chol-siRNA) did not result in a significant loss
Lipoplex Formation Using Liposomes Prepared by Ethanol Injection
Cationic liposomes composed of 3β-[N -(N� N� –dimethylaminoethane)carbamoyl] cholesterol (DC–Chol) and dioleoylphosphatidylethanolamine (DOPE) (DC–Chol/DOPE liposome, molar ratio, 1:1 or 3:2) prepared by the dry-film method
LPD Nanoparticles-Novel Nonviral Vector for Efficient Gene Delivery
. One is composed of cationic lipid d io leoyl-t rimethyla mmonium p ropane (DOTAP) and cholesterol at molar ratio of 1:1. The other is composed of cationic lipid 3β(N-(N’, N’-d imethylaminoethane) c arbamoyl) chol esterol (DC-Chol) and neutral lipid d io leoylp
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