Methylhomatropine (bromide)

一种抗胆碱能药物；体外阻断乙酰胆碱诱发的大鼠和兔肠道痉挛（ED50s分别为0.052和0.011mg/kg）；减缓大鼠肠道中木炭粉的运输（ED50=27mg/kg）并阻断兔唾液腺分泌（ED50=0.16mg/kg）；皮下或口服给药可引起小鼠瞳孔散大（ED50s分别为0.13和12mg/kg）。An anticholinergic agent; blocks acetylcholine-induced spasm of rat and rabbit intestines ex vivo (ED50s = 0.052 and 0.011 mg/kg, respectively); slows intestinal transit of a charcoal meal in rats (ED50 = 27 mg/kg) and blocks salivary gland secretion in rabbits (ED50 = 0.16 mg/kg); induces mydriasis in mice when administered subcutaneously or orally (ED50s = 0.13 and 12 mg/kg, respectively).