Umirolimus

雷帕霉素衍生物；具有免疫抑制和抗炎作用；将细胞周期停止在G1期；抑制人类平滑肌细胞增殖；当作为冠状动脉支架聚合物涂层的一部分使用时，可使猪过度拉伸模型中的狭窄程度减少50%。A rapamycin derivative; has immunosuppressive and anti-inflammatory effects; halts the cell cycle at the G1 phase; inhibits proliferation of human smooth muscle cells; reduces stenosis in a porcine overstretch model by 50% when administered as part of the polymer coating of a coronary stent.