20(S)-Ginsenoside Rh2

一种具有多种作用的天然类固醇糖苷；抑制RBL-2H3细胞释放β-己糖胺酶(IC50=100μM)，并在25mg/kg浓度下抑制小鼠IgE依赖性被动皮肤过敏反应；以剂量依赖性方式抑制HRA卵巢癌细胞和Bxpc-3胰腺癌细胞的生长；减少小鼠结肠直肠癌模型在强迫游泳测试中的不动时间；减少大鼠缺血再灌注诱发脑损伤模型中的梗塞体积。A natural steroid glycoside with diverse effects; inhibits release of β-hexosaminidase from RBL-2H3 cells (IC50 = 100 μM) and inhibits the IgE-dependent passive cutaneous anaphylaxis reaction in mice at a concentration of 25 mg/kg; inhibits growth of HRA ovarian and Bxpc-3 pancreatic cancer cells in a dose-dependent manner; decreases immobility time in the forced swim test in a mouse model of colorectal carcinoma; reduces infarct volume in a rat model of ischemia-reperfusion-induced brain injury.