2-Thiouridine

4－硫尿（嘧啶核）苷4－thiouridine

  　　缩写 s4 U。是存在于原核生物的 tRNA中的微量碱基，占据从 5′末端第 8位的特定位置。其特征是在 330毫微米处有最大的吸收。  

High Resolution Gene Expression Profiling of RNA Synthesis, Processing, and Decay by Metabolic Labeling of Newly Transcribed RNA Using 4-Thiouridine

RNA with 4-thiouridine to study the molecular mechanisms governing RNA synthesis, processing, and decay.

Introduction of Hypermodified Nucleotides in RNA

methylaminomethyl-2-thiouridine (mnm5 s2 U), methylcarboxymethyl-2-thiouridine (mcm5 s2 U), and 2-thiomethyl-N -6-carbamoylthreonyl-adenosine (ms2 t6 A). We also describe methods for using these nucleoside phosphoramidite reagents to synthesize RNA oligonucleotides