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一种广谱TK抑制剂,以纳摩尔浓度靶向HGF和VEGF受体TK家族成员以及KIT、Flt-3、PDGFRβ和Tie-2;在肺转移实验模型中减轻肿瘤负担。A broad-spectrum TK inhibitor that targets members of the HGF and VEGF receptor TK families, as well as KIT, Flt-3, PDGFRβ, and Tie-2, at nanomolar concentrations;reduces tumor burden in an experimental model of lung metastasis.
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Foretinib
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