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- Cayman
- 16027-10 mg
- 2025年07月15日
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人类CAR激动剂(EC50=49nM)；诱导肝细胞中人类CAR的核转位，进而增加CAR调控基因的表达。An agonist of human CAR (EC50 = 49 nM); induces nuclear translocation of human CAR in hepatocytes, followed by increased expression of CAR-regulated genes.
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Metabonomic Studies on Human Hepatocyte in Primary Culture
have been detailed in an approach enabling to separate drug-induced (endogenous metabolites) and drug-related (drug metabolites) biomarkers for reference inducers. Rifampicin, a nuclear pregnane X receptor (PXR) ligand; CITCO, a nuclear constitutive androstane
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CITCO
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