Ganglioside GM3 (bovine brain)

具有C18:1和C20:1鞘氨醇骨架的神经节苷脂GM3；通过调节细胞粘附、增殖和分化，在肿瘤细胞中表现出抗增殖和促凋亡作用；抑制血管生成并减少20μM时HUVEC的增殖和迁移；诱导胰岛素受体-caveolin-1复合物与脂质微区分离A ganglioside GM3 with C18:1 and C20:1 sphingoid backbones; demonstrates antiproliferative and pro-apoptotic effects in tumor cells by modulating cell adhesion, proliferation, and differentiation; suppresses angiogenesis and reduces proliferation and migration of HUVECs at 20 μM; induces dissociation of the insulin receptor-caveolin-1 complex from lipid microdomains.