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文献和实验-12)/interferon-γ (IFN-γ) in Th1 and IL-4/IL-13 in Th2] or costimulatory molecules (CD80/CD86) provided from antigen presenting cells (APC), and have several important immunological functions (1 ). Recently, several reports have shown that chemical mediators
Cyclooxygenase 2-Dependent Regulation of Antitumor Immunity in Lung Cancer
suppression (13 ,14 ). In contrast, IL-12 is critical for effective antitumor immunity (15 ,16 ). In both tumor models and patients, the tumor-bearing state induces lymphocyte and macrophage IL-10 but inhibits macrophage IL-12 production (5 ,6 ,17 –19
Osteoclast Formation in Mouse Co-cultures
The murine co-culture assay is used to generate mature osteoclasts from bone marrow precursors by culturing them with osteoblasts that are stimulated with 1,25-dihydroxy vitamin D3 and prostaglandin E2 . This assay is used particularly
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