TBB

一种CK2的抑制剂（IC50=0.15µM）；同时抑制PIM3和DYRK2（IC50分别为0.86和0.99µM），以及其他蛋白激酶，其IC50值均在低微摩尔范围内。但对于另外26种激酶，在浓度高达10µM时，抑制作用均小于10%。An inhibitor of CK2 (IC50 = 0.15 µM); inhibits PIM3 and DYRK2 (IC50s = 0.86 and 0.99 µM, respectively) and other protein kinases with IC50 values in the low micromolar range but displays less than 10% inhibition at 26 additional kinases up to 10 µM .