Caspase-8 Monoclonal Antibody

抗原：人类caspase-8氨基酸PVETDSEEQP；宿主：小鼠，克隆90A992；同种型：IgG1；交叉反应：(+)人类、黑猩猩和恒河猴caspase-8；应用：FC、IHC（石蜡包埋组织）和WB；Caspase-8在CD95激活和caspase通路之间形成直接联系。caspase-8过度表达会诱导细胞凋亡，而ICE家族特异性抑制剂可阻止这种凋亡。Antigen: human caspase-8 amino acids PVETDSEEQP; Host: mouse, clone 90A992; Isotype: IgG1; Cross Reactivity: (+) human, chimpanzee, and Rhesus monkey caspase-8; Application(s): FC, IHC (paraffin-embedded tissue), and WB; Caspase-8 forms a direct link between the activation of CD95 and the caspase pathway. Overexpression of caspase-8 induces apoptosis, which can be blocked by inhibitors specific for the ICE family.