IRAK-1 Polyclonal Antibody

抗原：对应于人IRAK-1氨基酸700-712的合成肽；宿主：兔；交叉反应性：(+)人和小鼠IRAK-1；(−)IRAK-2；应用：IP和WB；IRAK-1在与IL-1结合后与IL-1受体亚基IL-1RI和IL-1RAcP相关，并充当信号分子来介导IL-1反应。它介导信号级联，导致IL-1家族成员（包括IL-1和IL-18）激活NF-κB。Antigen: synthetic peptide corresponding to human IRAK-1 amino acids 700-712; Host: rabbit; Cross Reactivity: (+) human and mouse IRAK-1; (−) IRAK-2; Application(s): IP and WB; IRAK-1 is associated with the IL-1 receptor subunits IL-1RI and IL-1RAcP after IL-1 binding and serves as a signaling molecule to mediate IL-1 response. It mediates a signaling cascade leading to NF-κB activation by members of the IL-1 family including IL-1 and IL-18.