4-Quinolone-3-Carboxamide CB2

CB2受体的选择性高亲和力配体（体外Ki=0.6nM，而CB1结合Ki>10,000nM）可作为反向激动剂；在小鼠福尔马林试验中，剂量为6mg/kg时表现出抗伤害活性A selective, high-affinity ligand of the CB2 receptor (Ki = 0.6 nM v. CB1 binding at a Ki >10,000 nM in vitro) that may behave as an inverse agonist; displays antinociceptive activity in a formalin test in mice at a dose of 6 mg/kg.