trans-trismethoxy Resveratrol

一种具有多种生物活性的二苯乙烯；对多种癌细胞系具有细胞毒性，包括PC3、KB、HT-29、SW480和HL-60细胞（IC50s分别为3.6、10.2、16.1、54和2.5µM）；在报告试验中，15µM可抑制HEK293T细胞中TNF-α诱导的NF-κB活化；0.1µM可抑制斑马鱼胚胎中的血管生成A stilbene with diverse biological activities; cytotoxic to several cancer cell lines, including PC3, KB, HT-29, SW480, and HL-60 cells (IC50s =3.6, 10.2, 16.1, 54, and 2.5 µM, respectively); inhibits TNF-α-induced activation of NF-κB in HEK293T cells in a reporter assay at 15 µM; inhibits angiogenesis in zebrafish embryos at 0.1 µM.