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SIRT2 (human, recombinant)

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  • ¥1
  • Cayman已认证
  • 10011191-100 µg
  • 2025年07月13日
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    来源:活性重组N端六组氨酸标记酶氨基酸2-389,在大肠杆菌中表达;分子量:44.2kDa;SIRT2是一种细胞质蛋白,负责组蛋白H4和α-微管蛋白的去乙酰化,这是一种对控制细胞周期很重要的修饰。SIRT2与HDAC6和微管共定位,并作为有丝分裂检查点,防止可能导致超倍体细胞的染色体不稳定性Source: Active recombinant N-terminal hexahistidine-tagged enzyme amino acids 2-389, expressed in E. coli; MW: 44.2 kDa; SIRT2 is a cytoplasmic protein responsible for the deacetylation of histone H4 and α-tubulin, a modification important for controlling the cell cycle. SIRT2 co-localizes with HDAC6 and microtubules and functions as a mitotic checkpoint in preventing chromosomal instability that can lead to hyperploid cells.

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