PTEN (human recombinant)

来源：从Sf21细胞中纯化的活性人类重组N端His标记蛋白；分子量：50.8kDa；PTEN通过去磷酸化Akt和PIP3等蛋白质和脂质，在许多信号转导途径中起关键调节酶的作用。PTEN突变会导致许多人类癌症，包括黑色素瘤和前列腺癌，使PTEN成为重要的肿瘤抑制因子Source: Active human recombinant N-terminal His-tagged protein purified from Sf21 cells; MW: 50.8 kDa; PTEN functions as a key regulatory enzyme in many signal transduction pathways by dephosphorylating proteins and lipids such as Akt and PIP3. Mutation of PTEN results in many human cancers including melanoma and prostate carcinoma, making PTEN an important tumor suppressor.