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PTEN (human recombinant)

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  • ¥1
  • Cayman已认证
  • 10009746-50 µg
  • 2025年07月13日
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    来源:从Sf21细胞中纯化的活性人类重组N端His标记蛋白;分子量:50.8kDa;PTEN通过去磷酸化Akt和PIP3等蛋白质和脂质,在许多信号转导途径中起关键调节酶的作用。PTEN突变会导致许多人类癌症,包括黑色素瘤和前列腺癌,使PTEN成为重要的肿瘤抑制因子Source: Active human recombinant N-terminal His-tagged protein purified from Sf21 cells; MW: 50.8 kDa; PTEN functions as a key regulatory enzyme in many signal transduction pathways by dephosphorylating proteins and lipids such as Akt and PIP3. Mutation of PTEN results in many human cancers including melanoma and prostate carcinoma, making PTEN an important tumor suppressor.

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    • PTEN and Cancer

      Genetic evidence strongly suggested that a tumor suppressor was located on chromosome 10. During the development of glioblastoma, one copy of chromosome 10 was typically lost (1 ). Cytogenetic and molecular analysis revealed partial

    • Construction of Recombinant Human Cytomegalovirus

      The use of reverse genetics to generate recombinant viruses allows the researcher to investigate the exact functional significance of particular viral genes during the virus life cycle, by means of their deletion or modification in the viral

    • Delivery of Recombinant Adenoviruses to Human Saphenous Vein

      The human saphenous vein is the most commonly used conduit for coronary artery bypass grafting owing to its ready availability, ease of harvesting, and favorable surgical handling (1 ). However, it suffers from a progressive decline

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