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- 2025年07月16日
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文献和实验4,5-bisphosphate to produce the second messengers, myo -inositol(1,4,5)trisphosphate [Ins(1,4,5)P3 ] and diacylglycerol (1 ). Ins(1,4,5)P3 interacts with a specific receptor that is a ligand-gated channel that allows mobilization of non-mitochondrial intracellular
Caged Intracellular Messengers and the Inositol Phosphate Signaling Pathway
, derived from work in the author’s laboratory using caged inositol trisphosphate to study signaling in Xenopus oocytes.
Hormones, neurotransmitters, chemoattractants, and growth factors all elicit intracellular responses, on binding to cell surface receptors, by activating inositol phospholipid-specific phospholipase C (PLC). Activated PLC catalyzes
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