Prostaglandin D Synthase (lipo

脂质运载蛋白类型的前列腺素D合成酶（L-PGDS，又称β-微量蛋白）是一种同二聚体，其每个亚基的大小因糖基化程度不同而在20-31 kDa之间变化。L-PGDS具有两种功能：催化PGH2转化为PGD2，并作为脂质类分子（如维甲酸和甲状腺激素）的载体蛋白。L-PGDS存在于多种体液中，包括脑脊液、精液和血浆。Cayman的L-PGDS（人源）ELISA是一种免疫测定（即夹心法）ELISA，标准曲线范围为1.56-100 ng/ml，检测限为1.56 ng/ml。该检测方法已在脑脊液中验证，脑脊液中的L-PGDS含量约为12-30 µg/ml。Lipocalin-type PGDS (a.k.a., β-trace) is a homodimer with each subunit ranging in size from 20-31 kDa, depending on the extent of glycosylation. L-PGDS has two functions: it catalyzes the conversion of PGH2 to PGD2 and acts as a carrier protein for lipid-like molecules (i.e., retinoids and thyroid hormones). L-PGDS is present in a variety of body fluids including cerebrospinal fluid, seminal fluid, and plasma. Cayman's L-PGDS (human) ELISA is an immunometric (i.e., sandwich) ELISA with a standard curve ranging from 1.56-100 ng/ml and a limit of detection of 1.56 ng/ml. This assay has been validated using CSF which contains approximately 12-30 µg/ml of L-PGDS.