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文献和实验Assaying Peptide Translocation by the Peptide Transporter TAP
. The peptide transporter TAP translocates peptides over this ER membrane which is critical for successful MHC class I antigen presentation. How peptide translocation by TAP can be assayed and inhibitors of chemical or viral origin can be identified
Photolabeling the Transporter Associated with Antigen Processing
in cellular membranes, and the identification of novel peptide-binding proteins (3 -5 ). Crosslinkers function by coupling reactive groups to amino acid side chains of peptides, and are divided into two groups; homobifunctional or heterobifunctional
Peptide-receptive MHC class I molecules and the TAP (transporter associated with antigen processing) peptide transporter are known to leave the ER and cycle through the cis side of the Golgi apparatus. The amount, and the extent
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