兔多克隆磷酸化组蛋白H1抗体 WB/IC 磷酸化组蛋白h1抗

体

价格询价

货号06-597
更新日期2025年07月12日

应用范围Western Blotting;Immunocytochemistry
宿主Rabbit
适应物种Bovine;Human

默克生命科学

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详细信息
文献和实验
技术资料

应用范围：
Western Blotting;Immunocytochemistry
宿主：
Rabbit
适应物种：
Bovine;Human
库存：
大量
抗原来源：
0
是否单克隆：
2
规格：
200 μg

Product Images

WB: Colcemid treated (lane 1) and untreated (lane 2) HeLa cell lysate probed with anti-phospho-Histone H1 (2μg/ml)

Species Reactivity	Key Applications	Host	Format	Antibody Type
B, H	IC, WB	Rabbit	Purified	Polyclonal Antibody

Description:

Anti-phospho-Histone H1

Background Information:

Histone H1 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N-terminal tail, H1 is involved with the structure of the nucleosomes of the 'beads on a string' structure.

The N-terminal tail of histone H1 protrudes from the globular nucleosome core and can undergo several different types of epigenetic modifications that influence cellular processes. These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine.

Specificity:

Recognizes phospho-Histone H1, Mr 32 kDa. Additional proteins were also detected, Mr 66 and 100 kDa.

Key Applications:

Immunocytochemistry
Western Blotting

Species Reactivity:

Bovine
Human

Isotype:

IgG

Immunogen:

Hyper-phosphorylated isoform of tetrahymena Histone H1 purified by cation-exchange HPLC

Modifications:

Phosphorylation

Molecular Weight:

32 kDa

Control:

Colcemid treated HeLa cell lysate

Presentation:

Immunoaffinity Purified immunoglobulin in 0.02M Phosphate Buffer, 0.25 M NaCl, pH 7.6 with 15 mg/mL BSA containing no preservatives.

Storage Conditions:

Maintain for 2 years at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Gene Symbol:

HIST1H1C
MGC3992
H1F2
H1.2

Quality Assurance:

Immunoblot Analysis: 0.5-2 μg/mL detected phosphorylated Histone H1 from acid extracts of colcemid treated HeLa cells but not untreated HeLa cells (Catalog # 17-306).

Immunocytochemistry: 5-10 μg/mL showed positive immunostaining for Histone H1 in mitotic HeLa cells fixed with 95% ethanol/5% glacial acetic acid (v/v).

Antibody Category:

Epigenetics & Nuclear Function

Antibody Sub-Category:

Histones

Usage Statement:

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Trade Name:

Upstate (Millipore)

Concentration:

1 mg/mL

Antibody Type:

Polyclonal Antibody

Format:

Purified

Host:

Rabbit

更多产品技术资讯，请访问密理博中国博客：http://blog.milliporechina.com

Hyper-phosphorylated isoform of tetrahymena Histone H1 purified by cation-exchange HPLC 详细描述见链接：http://www.millipore.com/catalogue/item/06-597

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兔多克隆磷酸化组蛋白H1抗体 WB/IC 磷酸化组蛋白h1抗

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