Anti-SEP15 Polyclonal Antibody

产品简介

英文名称	Anti-SEP15 Polyclonal Antibody
宿主	Rabbit
别名	SELENOF
稀释比例	WB 1:5000-8000. IHC 1:100-300.
蛋白分子量	14/18kDa
Gene ID	9403
保存	Store at -20°C. Avoid freeze / thaw cycles.
储存液	Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法	Octanoic acid-ammonium sulfate precipitation
亚型	IgG
免疫原	Recombinant protein of human SEP15
亚细胞定位	Cytoplasm
Swiss Prot	O60613
背景资料	The protein encoded by this gene belongs to the SEP15/selenoprotein M family. The exact function of this protein is not known; however, it has been found to associate with UDP-glucose:glycoprotein glucosyltransferase (UGTR), an endoplasmic reticulum(ER)-resident protein, which is involved in the quality control of protein folding. The association with UGTR retains this protein in the ER, where it may play a role in protein folding. It has also been suggested to have a role in cancer etiology. This protein is a selenoprotein, containing the rare amino acid selenocysteine (Sec). Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. Alternatively spliced transcript variants have been found for this gene.
Public Immunogen Range	1-165aa
克隆类型	Polyclonal Antibody
交叉反应	Human
应用	WB IHC
规格	50ul 100ul

备注：
以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。
These protocols are for reference only. Solarbio does not independently validate these methods.
实验图

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