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Anti-MLL/HRX, C-term., clone 9

-12; 200 μg
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  • 询价
  • 05-765
  • 2025年07月14日
  • Immunoprecipitation;Western Blotting
  • Mouse
  • Human;Mouse
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 应用范围：

      Immunoprecipitation;Western Blotting

    • 宿主：

      Mouse

    • 适应物种：

      Human;Mouse

    • 抗原来源：

      0

    • 库存：

      大量

    • 是否单克隆：

      1

    • 规格：

      200 μg

    Product Images

    WB: K562 nuclear extract was probed with anti-MLLC /HRX (1μg/ml).
    Species Reactivity Key Applications Host Format Antibody Type
    H, M IP, WB, Chromatin Immunoprecipitation (ChIP) Mouse Purified Monoclonal Antibody
    Description:
    Anti-MLL/HRX, C-term., clone 9-12
    Background Information:
    The acute lymphoblastic leukaemia (ALL)-1 (also known as MLL, HRX, HTRX, and TRX1) gene on human chromosome 11q23 is the site of many locally clustered chromosomal alterations associated with several types of acute leukaemias, including deletions, partial duplications and translocations. Structurally variant proteins derived from the altered gene presumably cause the malignant transformation of early haemopoietic progenitor cells.
    Clone:
    9-12
    Specificity:
    Recognizes the C-terminal proteolytic fragment of MLL (MLLC ).
    Key Applications:
    • Immunoprecipitation
    • Western Blotting
    • Chromatin Immunoprecipitation (ChIP)
    Application Notes:
    Immunoprecipitation : This antibody is reported to immunoprecipitate MLLC from nuclear extracts. The N-terminal fragment, MLLN (300kDa), is also co-immunoprecipitated by this antibody.
    Species Reactivity:
    • Human
    • Mouse
    Isotype:
    IgG1
    Immunogen:
    MBP fusion protein corresponding to residues 3084-3959 of human mixed lineage leukemia (MLL)
    Molecular Weight:
    180 kDa
    Control:
    K562 nuclear extract
    Presentation:
    Protein A Purified immunoglobulin in 30% glycerol, 0.07M Tris-glycine, pH 7.4, 0.105 M NaCl, 0.035% sodium azide as a preservative.
    Storage Conditions:
    Maintain for 2 years at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
    Gene Symbol:
    • MLL
    • HRX
    • CXXC7
    • ALL1
    • HTRX1
    • TRX1
    • FLJ11783
    • ALL-1
    • MLL/GAS7
    • HTRX
    • MLL1A
    Quality Assurance:
    Routinely evaluated by immunoblot on in nuclear extract from K562 cells
    Antibody Category:
    Epigenetics & Nuclear Function
    Antibody Sub-Category:
    Histones
    Usage Statement:
    Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    Trade Name:
    Upstate (Millipore)
    Concentration:
    1 mg/mL
    Antibody Type:
    Monoclonal Antibody
    Format:
    Purified
    Host:
    Mouse

    更多产品技术资讯，请访问密理博中国博客：http://blog.milliporechina.com

    MBP fusion protein corresponding to residues 3084-3959 of human mixed lineage leukemia (MLL) 详细描述见链接：http://www.millipore.com/catalogue/item/05-765

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