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Anti-p53, clone BP53-12; 200 μ

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  • 询价
  • 05-224
  • 2025年07月06日
  • Immunoprecipitation;Western Blotting
  • Mouse
  • Human
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 应用范围：

      Immunoprecipitation;Western Blotting

    • 宿主：

      Mouse

    • 适应物种：

      Human

    • 库存：

      大量

    • 抗原来源：

      0

    • 是否单克隆：

      1

    • 规格：

      200 μL

    Product Images

    WB: Raji cell lysate probed with anti-p53 at 1:1000 dilution
    Species Reactivity Key Applications Host Format Antibody Type
    H IH, IP, WB Mouse Purified Monoclonal Antibody
    Description:
    Anti-p53, clone BP53-12
    Background Information:
    The human wild-type p53 protein is a 393 amino acid nuclear phosphoprotein, present in the nucleus of all normal mammalian cells where it appears to be involved in the regulation of cell proliferation. The normal protein has a very short half-life and is present in only minute amounts in normal tissues and cells. In contrast, mutant p53 protein produced by malignant cells is usually a product of a point mutation in the p53 gene leading to substitution of a single amino acid that significantly prolongs the half-life of the protein. The accumulation of high levels of p53 is a potential novel marker for malignancy.
    Clone:
    BP53-12
    Specificity:
    Recognizes p53.
    Key Applications:
    • Immunohistochemistry
    • Immunoprecipitation
    • Western Blotting
    Species Reactivity:
    Human
    Isotype:
    IgG2a
    Immunogen:
    Recombinant human wild type p53
    Molecular Weight:
    53 kDa
    Control:
    Raji cell lysate
    Presentation:
    Protein G Purified immunoglobulin in Protein G Purified immunoglobulin in of 0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30%
    Storage Conditions:
    Maintain for 2 years at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
    Gene Symbol:
    • TP53
    • P53
    • TRP53
    • p53
    • LFS1
    Quality Assurance:
    routinely evaluated on RIPA lysate of human Raji cells
    Antibody Category:
    Epigenetics & Nuclear Function
    Antibody Sub-Category:
    Transcription Factors
    Usage Statement:
    Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    Trade Name:
    Upstate (Millipore)
    Concentration:
    Variable
    Antibody Type:
    Monoclonal Antibody
    Format:
    Purified
    Host:
    Mouse

    Product Family Information

    p53 Antibodies, Proteins & Kits

    Millipore’s Anti-p53 antibody demonstrates specificity against p53. See below for data, references and related products for p53. All Millipore antibodies are based on the expertise of Upstate & Chemicon.

    » More…


    更多产品技术资讯，请访问密理博中国博客：http://blog.milliporechina.com

    Recombinant human wild type p53 详细描述见链接：http://www.millipore.com/catalogue/item/05-224

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