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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃.
- 保质期:
Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.
- 英文名:
Recombinant Marmota monax Interferon gamma (IFNG)
- 库存:
200
- 供应商:
武汉华美生物工程有限公司
- 规格:
20μg
英文名称:
Recombinant Marmota monax Interferon gamma (IFNG)品名简称:
Recombinant Marmota monax IFNG protein货号:
CSB-YP011050MQG规格:
20μg价格:
2616LC-MS/Western Blot:
/SDS-PAGE:
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.纯度:
Greater than 90% as determined by SDS-PAGE.内毒素:
Not test生物活性:
/基因名:
IFNGUniprot No.:
O35735别名:
Short name: IFN-gamma种属:
Marmota monax (Woodchuck)蛋白长度:
Full Length of Mature Protein来源:
Yeast分子量:
18.6 kDa表达区域:
24-166aa氨基酸序列:
QDTVNKEIEDLKGYFNASNSNVSDGGSLFLDILDKWKEESDKKVIQSQIVSFYFKLFEHLKDNKIIQRSMDTIKGDLFAKFFNSSTNKLQDFLKVSQVQVNDLKIQRKAVSELKKVMNDLLPHSTLRKRKRSQSSIRGRRASK蛋白标签:
N-terminal 6xHis-tagged产品提供形式:
Liquid or Lyophilized powder缓冲液:
If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.储存条件:
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.保质期:
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.货期:
3-7 business days注意事项:
Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.功能1:
Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.功能2:
Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.文献:
"Molecular cloning of the woodchuck cytokines: TNF-alpha, IFN-gamma, and IL-6."Lohrengel B., Lu M., Roggendorf M.Immunogenetics 47:332-335(1998)研究领域:
Stem Cells请点击“在线询价”找客服索取产品说明书及引用文献目录,产品实时更新参数、价格信息、更多文献信息可以查看cusabio官网
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文献和实验移位到胞核,如干扰素刺激的基因因子2(interferon-stimulated gene fac-tor 2,ISGF2)和γ-干扰素激活因子(gamma-interferon activation factor,GAF或STAT91)结合到IFN基因启动子中两个称之为γ干扰素活化点(gamma-interferon activation site,GAS)和干扰素刺激的反应元件(interferon-stimulated response element,ISRE)的位置上。IFN-γ可促进
研究,其中包括了基因工程单链抗体(single chain Fv,scFv)的应用。一般抗体均大于150KD,不易渗透到组织中,而鼠源抗体用于人体易产生人抗鼠Ig抗体。应用基因工程技术产生的单链抗体是由Ig重链可变区(VH)和轻链可变区(VL)通过一段小肽连接在一起的重组蛋白。分子量仅为27KD,免疫原性降低,易于进入瘤组织,血中半衰期短,易于清除,无Fc段不会与具有Fc受体的正常细胞结合,并且易于产业化。为了提高显像效果Nieroda 用生物反应调节剂 g-干扰素与同位素标记抗体同时使用,促使肿瘤
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