EZClick™O-GlcNAc修饰糖蛋白测定试剂盒/EZC

产品名称：EZClick™O-GlcNAc修饰糖蛋白测定试剂盒/EZClick™O-GlcNAc修饰糖蛋白测定试剂盒/EZClick™O-GlcNAc修饰糖蛋白测定试剂盒-EZClick™ O-GlcNAc Modified Glycoprotein Assay Kit /EZClick™ O-GlcNAc Modified Glycoprotein Assay Kit /EZClick™ O-GlcNAc Modified Glycoprotein Assay Kit

产品货号：K714-100

产品规格：100assays

背景资料：待更新

保存建议：EZClick™O-GlcNAc修饰糖蛋白测定试剂盒/EZClick™O-GlcNAc修饰糖蛋白测定试剂盒/EZClick™O-GlcNAc修饰糖蛋白测定试剂盒-EZClick™ O-GlcNAc Modified Glycoprotein Assay Kit /EZClick™ O-GlcNAc Modified Glycoprotein Assay Kit /EZClick™ O-GlcNAc Modified Glycoprotein Assay Kit -20°C

产品描述：Glycans are vital components of glycoproteins, glycolipids, and proteoglycans in all domains of life. Glycoproteins are grouped by the type of carbohydrate and amino acid linkage site. N-linked glycosylation is a modification of asparagine, whereas O-linked glycosylation occurs through the hydroxyl group of serine and threonine residues. Glycosylation occurs co- or post-translationally on >50% of eukaryotic proteins resulting in membrane-associated, intracellular, or secreted glycoproteins that are crucial in cellular processes, protein bioactivity and metabolic turnover. Modification by O-linked-N-acetyl glucosamine (O-GlcNAc) has rapidly emerged as a major cellular signaling mechanism with number of modified targets similar to protein phosphorylation. Many oncogenes and tumor suppressors are regulated by O-GlcNAcylation. O-GlcNAc modification is ubiquitous among eukaryotes, from yeast to humans and its modifying enzymes have been well characterized. O-GlcNAc modified nuclear and cytosolic targets include: transcription factors, signaling proteins, metabolic enzymes, mitochondrial trafficking, cell cycle regulation, glucose homeostasis. O-GlcNAc glycosylation is implicated in normal brain functions, etiology of neurodegeneration, type II diabetes, and pathways involved in morphogenesis and virulence factors of microbes and plant host cells. Since glycoproteins are not directly encoded in the genome, methods of characterization and analyses of glycoproteins are of great interest. Thus BioVision offers EZClickTM O-GlcNAc Modified Glycoprotein Assay Kit, a highly specific, simple and robust method for labeling and detection of O-GlcNAc-glycosylated proteins within cells. We use a modified glucosamine precursor that is fed directly into the cells, processed by the hexosamine pathway and incorporated into the proteins. Followed by click reaction with alkyne-containing dye, this system offers a powerful method for imaging the localization, trafficking, and dynamics of glycans, or detection by FACS for quantitative studies. Labeled Glycoproteins can be directly detected in 1D or 2D gels using the appropriate excitation sources, or enriched by immunoprecipitation with biotin-alkyne or antibodies prior to proteomic analysis. We provide sufficient materials for 100 assays in a 96-well plate format

点击：EZClick™O-GlcNAc修饰糖蛋白测定试剂盒/EZClick™O-GlcNAc修饰糖蛋白测定试剂盒/EZClick™O-GlcNAc修饰糖蛋白测定试剂盒-EZClick™ O-GlcNAc Modified Glycoprotein Assay Kit /EZClick™ O-GlcNAc Modified Glycoprotein Assay Kit /EZClick™ O-GlcNAc Modified Glycoprotein Assay Kit 查看更详细产品说明，更多应用、储存、价格、货期等信息请致电垂询BioVision中国区域授权总代理艾美捷科技有限公司。更多特色试剂盒、特色抗体以及特色试剂等产品评论，请点击查看每日生物评论网站。

BioVision的公司总部在美丽的旧金山湾地区，它是全球生命科学公司的领路人.BioVision在开发和研究细胞凋亡检测分析、代谢检测方面具有卓越的影响力.包括检测各种检测分析试剂盒、相关特色抗体、重组蛋白及细胞因子和酶等多种产品，以及其他创新的研究工具.其产品覆盖细胞凋亡研究、能量代谢、细胞/组织蛋白提取、氧化应激与损伤、代谢与肥胖症、细胞增殖与毒性、信号转导、干细胞研究等领域.作为多家知名品牌的中国总代理以及中国区域代理，艾美捷与BioVision一起为研究者们提供最好、崭新的细胞生物学研究工具而不断扩大产品及服务质量.

艾美捷科技有限公司，通过提供完整的产品和服务体系、便利的客户关系和供应链管理，为生命科学研究工作者提供整体打包方案。我们的企业的核心价值观：“激情、敬业、学习、创新、合作、卓越”。激发我们内在的创造力，提供有竞争力的生物医学产品和服务，持续为客户创造最大价值是我们的企业使命。我们的企业愿景是成为受人尊重、世界知名的生物医学产品及服务供应商。艾美捷科技与国内外优秀的生物试剂供应商保持着密切的合作关系，目前已成为众多国际知名品牌的中国总代理或一级代理，主要包括：AmyJet、AAT Bioquest、Abnova、Agrisera、Biovision、Biosensis、Cayman Chemical、Caisson Labs、Cytoskeleton、CytoNiChe、Epigentek、Equitech-Bio、Hycult Biotech、Jackson、LifeSensors、ProSpec、Norgen Biotek、Mabtech、Matreya、iRegene、StressMarq、ImmunoReagents、SouthernBiotech、Origene、US Biological、Solis BioDyne等，可以在第一时间为用户提供最前沿的专业资讯、完备的产品及物流服务。艾美捷服务升级，全方位实验服务项目上线啦~

关键词：细胞分析试剂盒，EZClick™O-GlcNAc修饰糖蛋白测定试剂盒/EZClick™O-GlcNAc修饰糖蛋白测定试剂盒/EZClick™O-GlcNAc修饰糖蛋白测定试剂盒，待更新