Human CellExp™ BAFF, Mouse Rec

产品名称：Human CellExp™BAFF，小鼠重组/Human CellExp™BAFF，小鼠重组/Human CellExp™BAFF，小鼠重组-Human CellExp™ BAFF, Mouse Recombinant/Human CellExp™ BAFF, Mouse Recombinant/Human CellExp™ BAFF, Mouse Recombinant

产品货号：P1370-10

产品规格：10ug

来源宿主：待更新

保存建议：Human CellExp™BAFF，小鼠重组/Human CellExp™BAFF，小鼠重组/Human CellExp™BAFF，小鼠重组-Human CellExp™ BAFF, Mouse Recombinant/Human CellExp™ BAFF, Mouse Recombinant/Human CellExp™ BAFF, Mouse Recombinant-20°C

背景资料：B-cell activating factor (BAFF), also known as tumor necrosis factor ligand superfamily member 13B , TNFSF13B, BAFF, B Lymphocyte Stimulator (BLyS), cluster of differentiation 257 (CD257), DTL, TNF- and APOL-related leukocyte expressed ligand (TALL-1), THANK, TNFSF20, ZTNF4, and is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptors TNFRSF13B/TACI, TNFRSF17/BCMA, and TNFRSF13C/BAFFR. This cytokine is expressed in B cell lineage cells, and acts as a potent B cell activator. It has been also shown to play an important role in the proliferation and differentiation of B cells. It is expressed as transmembrane protein on various cell types including monocytes, dendritic cells and bone marrow stromal cells. BAFF is the natural ligand of three unusual tumor necrosis factor receptors named BAFF-R, TACI, and BCMA, all of which have differing binding affinities for it. These receptors are expressed mainly on mature B lymphocytes (TACI is also found on a subset of T-cells and BCMA on plasma cells). TACI binds worst since its affinity is higher for a protein similar to BAFF, called a proliferation-inducing ligand (APRIL). BCMA displays an intermediate binding phenotype and will work with either BAFF or APRIL to varying degrees. Signaling through BAFF-R and BCMA stimulates B lymphocytes to undergo proliferation and to counter apoptosis. All these ligands act as heterotrimers (i.e. three of the same molecule) interacting with heterotrimeric receptors, although BAFF has been known to be active as either a hetero- or homotrimer. BAFF acts as a potent B cell activator and has been shown to play an important role in the proliferation and differentiation of B cells.

点击：Human CellExp™BAFF，小鼠重组/Human CellExp™BAFF，小鼠重组/Human CellExp™BAFF，小鼠重组-Human CellExp™ BAFF, Mouse Recombinant/Human CellExp™ BAFF, Mouse Recombinant/Human CellExp™ BAFF, Mouse Recombinant查看更详细产品说明，更多应用、储存、价格、货期等信息请致电垂询BioVision中国区域授权总代理艾美捷科技有限公司。更多特色试剂盒、特色抗体以及特色试剂等产品评论，请点击查看每日生物评论网站。

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关键词：Human CellExp™ BAFF, Mouse Recombinant/Human CellExp™ BAFF, Mouse Recombinant/Human CellExp™ BAFF, Mouse Recombinant，Human CellExp™BAFF，小鼠重组/Human CellExp™BAFF，小鼠重组/Human CellExp™BAFF，小鼠重组，TNFSF13B, BAFF, BLYS, CD257, DTL, TALL-1, TALL1, THANK, TNFSF20, ZTNF4