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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Full length recombinant LEF-1 protein. UniProt: Human, Q9UJU2, Mouse, P27782
- 亚型:
IgG1
- 形态:
Liquid
- 保存条件:
Store at -20°C.
- 克隆性:
Monoclonal
- 适应物种:
Human, Mouse
- 抗原来源:
P27782!!AIR8!!Q9UJU2
- 级别:
分子生物学级
- 供应商:
Agrisera
- 宿主:
Mouse
- 应用范围:
1 : 1000 or 1 µg/ml (IF), 1-5 µg/ml (WB) The optimal working dilution should be determined by the investigator.
- 靶点:
Lymphoid Enhancer Factor -1 is a transcription factor included in the High Mobility Group of DNA binding proteins. It belongs to the family of four proteins referred to as LEF/TCF transcription factors. These factors play an important role in WNT signalin
- 抗体名:
LEF-1 beta catenin | Lymphoid Enhancer Factor -1 (clone REMB1)
- 规格:
100 µg
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文献和实验Mapping of the Wnt/-Catenin/TCF Response Elements in the Human Versican Promoter
activator β-catenin is the key mediator of the canonical Wnt signaling pathway. However, β-catenin does not itself bind DNA and thus functions via interaction with TCF/Lymphoid-enhancing factor (LEF) transcription factors. These proteins contain a high
v468.chapter 1 经典 Wnt/b-Catenin 信号通路 (英文完整版)
-binding protein;Tcf , T-cell factor; Lef , lymphoid enhancer factor; Bcl9 , B-cell lymphoma-9; Dvl, ; b-cat, b-catenin; PYG , Pygopus. (For more details, I recommend the Wnt homepage: http://www.stanford.edu/~rnusse/Wntwindow.html ). Reprinted
v468 Chapter 9 自身启动子报告基因验证转录靶点
of the canonical Wnt signaling pathway.However, b-catenin does not itself bind DNA, but functions via interaction with T-cell factor (TCF)/lymphoid-enhancing factor (LEF) transcription factors. These proteins contain a high-mobility group(HMG) box that binds DNA
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