- 询价
- Agrisera
- 瑞典
- AS13 2688
- 2025年11月24日
- 1 : 200-1 : 2000 is recommended. Optimal dilutions/concentrations should be determined by the end user.
- Rabbit
- Purified saporin
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- 详细信息
- 询价记录
- 文献和实验
- 技术资料
- 免疫原：
Saporin, whole molecule
- 形态：
Lyophilized
- 保存条件：
For long term stability requires storage, preferab
- 克隆性：
Polyclonal
- 适应物种：
Purified saporin
- 级别：
分子生物学级
- 供应商：
Agrisera
- 宿主：
Rabbit
- 应用范围：
1 : 200-1 : 2000 is recommended. Optimal dilutions/concentrations should be determined by the end user.
- 靶点：
Saporin is a ribosome-inactivating protein (RIP) of type I. This monomeric RNA N-glycosidase purified from seeds of the plant Saponaria officinalis also known as Soapwort, is capable of specific depurination of eukaryotic ribosomes thus arresting protein
- 抗体名：
Saporin
- 规格：
100 µl
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- 作者
- 内容
- 询问日期
文献和实验New genes useful in suicide gene therapy are those encoding toxins such as plant ribosome-inactivating proteins (RIPs), which can irreversibly block protein synthesis, triggering apoptotic cell death. Plasmids expressing a cytosolic saporin
Comparison of Immunotoxins Bearing a Single Saporin Molecule with Multiple Toxin Conjugates
Immunotoxins (IT) constructed by conventional chemical means using heterobifunctional crosslinking reagents such as [N -succinimidyl 3-(2-pyridyldithio) propionate (SPDP) or 4-succinimidyloxycarbonyl-α methyl-α-(2-pyridyldithio) toluene (SMPT
a lectin B-chain for cell entry, and thus have a low toxicity for whole cells. Type I RIPs such as saporin can be easily purified (4 ) and have been successfully used to generate potent ITs, displaying antitumor activity both in vitro (5 ) and in vivo (6 ).
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