- 询价
- Agrisera
- 瑞典
- AS13 2659
- 2026年05月29日
- 1: 500 (Co-IP), 1 : 500 (WB)
- Rabbit
- Arabidopsis thaliana
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- 询价记录
- 文献和实验
- 技术资料
- 免疫原：
KLH-conjugated synthetic peptide derived from Arabidopsis thaliana CCA1 protein sequence, UniProt:P92973, TAIR:AT2G46830
- 形态：
Lyophilized
- 保存条件：
Store lyophilized/reconstituted at -20°C; once rec
- 克隆性：
Polyclonal
- 标记物：
Hung er al. (2018). The Arabidopsis LDL1/2-HDA6 histone modification complex is functionally associated with CCA1/LHY in regulation of circadian clock genes. Nucleic Acids Res. 2018 Aug 14. doi: 10.1093/nar/gky749.
- 适应物种：
Arabidopsis thaliana
- 抗原来源：
P92973
- 级别：
分子生物学级
- 供应商：
Agrisera
- 宿主：
Rabbit
- 应用范围：
1: 500 (Co-IP), 1 : 500 (WB)
- 靶点：
CCA1 (Circadian clocl associated 1) encodes a transcriptional repressor that performs overlapping functions with LHY in a regulatory feedback loop that is closely associated with the circadian oscillator of Arabidopsis. Binds to the evening element in the
- 抗体英文名：
Important note about protein extractionTranscription factors are best isolated by freezing nucelar extract in liquid nitrogen after addition of extraction buffer, followed by thawing directly at 100°C heating block, not at RT. Centrifugation for 5 minutes
- 抗体名：
CCA1 | Circadian clock associated 1
- 规格：
50 µg
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- 作者
- 内容
- 询问日期
文献和实验Assessment of Circadian and Light‐Entrainable Parameters in Mice Using Wheel‐Running Activity
, physiological variables are regulated by an internal clock. This endogenous circadian (?24?hr) clock enables organisms to anticipate daily environmental changes and modify behavioral and physiological functions appropriately. Processes regulated by the circadian
首先通过生物节律转录组学发现在衰老过程中肝脏呈节律性变化的脂质代谢相关生物学过程基因数量显著减少，肝脏出现明显的脂质积累；已知调控肝脏脂质代谢的生物节律关键分子 Bmal1、Clock 的调控作用明显逆转。这一发现提示在衰老过程中肝脏脂质代谢与生物节律出现解耦联现象。 图 1. 随着年龄增长，肝脏脂质代谢生物节律发生紊乱 为了寻找耦联分子，研究团队进一步分析转录组学，筛选到 Egr-1 表达的昼夜节律在雄性小鼠中随着年龄的增长而向前移动。Egr-1 是脂质代谢的重要调节剂。胰岛素增强
reinvigoration.Cancer Cell,2026 Jul 13 [4]MARCHF6 orchestrates hepatic lipid homeostasis by targeting SREBP1 for ER-associated degradation.J Hepatol,2026 May 22 [5]NDRG2 Orchestrates Circadian Clock Stability to Suppress Tumorigenesis and Potentiate Oxaliplatin
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