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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
KLH-conjugated synthetic peptide derived from N-terminal domain of Arabidopsis thaliana HTR12 AT1G01370 (Q8RVQ9)
- 形态:
Lyophilized
- 保存条件:
Store lyophilized/reconstituted at -20°C; once rec
- 克隆性:
Polyclonal
- 适应物种:
Arabidopsis thaliana
- 抗原来源:
Q8RVQ9
- 级别:
分子生物学级
- 供应商:
Agrisera
- 宿主:
Rabbit
- 应用范围:
1 : 50-1 : 500 (IHC), 1 : 200-1 : 2000 (WB)
- 靶点:
Histone H3-like centromeric protein HTR12 replaces formal H3 in the nucleosome core of centromeric chromatin at the inner plate of the kinetochore. It is required for the assembly of kinetochore proteins, mitotic progression and chromosome segregation. Lo
- 抗体英文名:
This product can be sold containing ProClin if requested
- 抗体名:
HTR12 | Histone H3-like centromeric protein
- 规格:
100 µl
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文献和实验Detection of Histone H3 Phosphorylation in Cultured Cells and Tissue Sections by Immunostaining
Growth factor stimulation results in phosphorylation of histone H3 at ser 10 and this correlated with expression of immediate early genes suggesting that this phosphorylation is associated with transcriptional activation. Although Western
组蛋白是和染色体相联的最主要的蛋白质。它的作用是和染色体中的 DNA 的负电荷结合。组蛋白是比较小的碱性蛋白;在细胞正常 pH 值时,组蛋白带有正电荷,这样它们就可以和 DNA 结合,这个正电荷主要存在于碱性氨基酸 Lys 和 Arg 的 -NH3 上。其实,组蛋白约含 25% 的 Arg 和 Lys 。比其他蛋白的 Arg , Lys 的含量都多。和真核 DNA 结合的有 5 种类型的组蛋白: H1 , H2A , H2B , H3
Histone Acetylation and Deacetylation
transcription (1 ,2 ). DNA is packaged into chromatin, a highly organized and dynamic protein-DNA complex. The fundamental subunit of chromatin, the nucleosome, is composed of an octomer of four core histones, an H3/H4 tetramer and two H2A/H2B dimers, surrounded
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