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- 详细信息
- 文献和实验
- 技术资料
- 抗体名:
NCAM 2 | Neural cell adhesion molecule 2
- 抗体英文名:
NCAM 2 | Neural cell adhesion molecule 2
- 靶点:
N-CAM 2 is a cell adhesion molecule belonging to the immunoglobulin superfamily. It is differentially expressed in the developing and mature olfactory epithelium and is involved in the guidance of developing olfactory sensory neurons to the glomeruli of t
- 应用范围:
Immunohistochemistry (IHC), Western blot (WB)
- 宿主:
Rabbit
- 适应物种:
Mouse
- 抗原来源:
O35136
- 级别:
Affinity purified IgG
- 供应商:
Agrisera AB
- 克隆性:
单克隆
- 保存条件:
Store lyophilized/reconstituted at -20°C; once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please, remember to spin tubes briefly prior to opening them to avoid any losses that might occur from lyophilized material adhering to the ca
- 形态:
Lyophilized in PBS pH 7.4
- 免疫原:
Recombinant polypeptide corresponding to amino acid residues 442-685 of mouse N-CAM O35136
- 规格:
100 µg
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文献和实验神经细胞粘着分子(neural cell adhesion molecule,N-CAM)
N-CAM是膜糖蛋白,至少以三种形式存在,但都是由同一基因编码。其中两种是跨膜蛋白,第三种共价结合在细胞质膜的外表面。无论是何种存在方式,N-CAM分子都有一部分伸出到细胞外表面。三种N-CAM在细胞外的结构都一样,都含有与细胞粘着相关的结合位点。 将分离纯化的N-CAM加入到人工磷脂脂质体中, 这种人工脂质体能够相互粘着,但是加入了相应的抗体就不会发生粘着, 不加N-CAM的人工脂质体也不会发生粘着。由此可以推测:细胞粘着是由细胞质膜中的蛋白分子介导的,N
In Vitro Migration Assays of Neural Stem Cells
and environmental factors, such as the polysialylated form of neural cell adhesion molecule (NCAM) or chemokines such as CXCL12, in the directional migration of neural precursors.
Neuronal Growth-Promoting and Inhibitory Cues in Neuroprotection and Neuroregeneration
that bind to CAMs on the surface of other axons or nonneuronal cells. In vitro assays have established the importance of the CAMs ((neural cell adhesion molecule NCAM), N-cadherin, and L1) in promoting axonal growth over cells. Compelling evidence implicates
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