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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Recombinant human S5a Proteasome subunit also known as Rpn10 P55036
- 形态:
Lyophilized
- 保存条件:
Store lyophilized/reconstituted at -20°C; once rec
- 克隆性:
Polyclonal
- 标记物:
Lundgren et al. (2003). Use of RNA interference and complementation to study the function of the Drosophila and human 26S proteasome subunit S13. Mol Cel Biol 23:5320-5330.
- 适应物种:
Human
- 抗原来源:
P55036
- 级别:
分子生物学级
- 供应商:
Agrisera
- 宿主:
Rabbit
- 应用范围:
1 : 2000 (WB)
- 靶点:
Proteasome-dependent degradation serves an essential role in the removal of a wide variety of key nuclear and cytosolic proteins. Substrates are targeted for proteolysis by the ubiquitin pathway before being degraded by the 26 S proteasome. The subunit of
- 抗体名:
S5a | human 26S proteasome subunit
- 规格:
100 µl
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文献和实验Assays for Proteasome Inhibition
with polyubiquitin chains through a cascade of enzyme-catalyzed events. These ‘marked’ proteins are then degraded via the 26S proteasome in an ATP-dependent manner (7 ). The 26S proteasome (EC 3.4.99.46) is a large, multisubunit enzyme (MW=2000 kDa) found in high
Studies of the Ubiquitin Proteasome System
of Unstable E3s in Bacterial Lysates Basic Protocol 25: Expression of E3s in Eukaryotic in Vitro Translation Systems Basic Protocol 26: Expression of Multi‐Subunit E3s Using a Baculovirus Expression System Support Protocol 5: Batch Purification of Multimeric E
Assays for Proteasome Assembly and Maturation
The 20S proteasome is a complex multisubunit protease that is present in all phylae of life. Eukaryotic 26S proteasomes, which are composed of 20S proteasomes and 19S activator complexes, mediate the degradation of ubiquitylated proteins
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