26S Proteasome Regulatory Subu

产品名称：26S Proteasome Regulatory Subunit 7 (PSMC2) Antibody-26S Proteasome Regulatory Subunit 7 (PSMC2) Antibody

产品货号：abx028160

产品规格：80ul#400ul

应用类型：WB

保存建议：26S Proteasome Regulatory Subunit 7 (PSMC2) Antibody-26S Proteasome Regulatory Subunit 7 (PSMC2) Antibody建议收到产品后，储存温度为-20°C。避免重复冻融

背景资料：26S Proteasome Regulatory Subunit 7 (PSMC2) Antibody is a Rabbit Poyclonal against 26S Proteasome Regulatory Subunit 7 (PSMC2). The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. This subunit has been shown to interact with several of the basal transcription factors so, in addition to participation in proteasome functions, this subunit may participate in the regulation of transcription. This subunit may also compete with PSMC3 for binding to the HIV tat protein to regulate the interaction between the viral protein and the transcription complex.

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关键词：26S Proteasome Regulatory Subunit 7 (PSMC2) Antibody，26S Proteasome Regulatory Subunit 7 (PSMC2) Antibody，待更新