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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃.
- 保质期:
Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.
- 英文名:
Recombinant Human Fos-related antigen 2 (FOSL2)
- 库存:
200
- 供应商:
武汉华美生物工程有限公司
- 规格:
20μg
英文名称:
Recombinant Human Fos-related antigen 2 (FOSL2)品名简称:
Recombinant Human FOSL2 protein货号:
CSB-EP008793HU规格:
20μg价格:
1344LC-MS/Western Blot:
/SDS-PAGE:
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.纯度:
Greater than 90% as determined by SDS-PAGE.内毒素:
Not test生物活性:
/基因名:
FOSL2Uniprot No.:
P15408别名:
FLJ23306; Fos L2; FOS like antigen 2; Fos related antigen 2; Fos-related antigen 2; FosL 2; Fosl2; FOSL2_HUMAN; FRA 2; FRA-2种属:
Homo sapiens (Human)蛋白长度:
Full Length来源:
E.coli分子量:
51.2 kDa表达区域:
1-326aa氨基酸序列:
MYQDYPGNFDTSSRGSSGSPAHAESYSSGGGGQQKFRVDMPGSGSAFIPTINAITTSQDLQWMVQPTVITSMSNPYPRSHPYSPLPGLASVPGHMALPRPGVIKTIGTTVGRRRRDEQLSPEEEEKRRIRRERNKLAAAKCRNRRRELTEKLQAETEELEEEKSGLQKEIAELQKEKEKLEFMLVAHGPVCKISPEERRSPPAPGLQPMRSGGGSVGAVVVKQEPLEEDSPSSSSAGLDKAQRSVIKPISIAGGFYGEEPLHTPIVVTSTPAVTPGTSNLVFTYPSVLEQESPASPSESCSKAHRRSSSSGDQSSDSLNSPTLLAL蛋白标签:
N-terminal 6xHis-SUMO-tagged产品提供形式:
Liquid or Lyophilized powder缓冲液:
If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.储存条件:
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.保质期:
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.货期:
13-23 business days注意事项:
Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.功能1:
Controls osteoclast survival and size. As a dimer with JUN, activates LIF transcription. Activates CEBPB transcription in PGE2-activated osteoblasts.功能2:
Controls osteoclast survival and size. As a dimer with JUN, activates LIF transcription. Activates CEBPB transcription in PGE2-activated osteoblasts.文献:
Isolation of human fos-related genes and their expression during monocyte-macrophage differentiation.Matsui M., Tokuhara M., Konuma Y., Nomura N., Ishizaki R.Oncogene 5:249-255(1990)研究领域:
Epigenetics and Nuclear Signaling请点击“在线询价”找客服索取产品说明书及引用文献目录,产品实时更新参数、价格信息、更多文献信息可以查看cusabio官网
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文献和实验Generation and Characterization of Bispecific Tandem Diabodies for Tumor Therapy
chain fusion products consisting of the V H domain from one antibody connected by a short linker to the V L domain of another antibody ( 11 , 12 ) ( see Chapter 18 of Arndt and Krauss in this issue) (Fig. 1C ). The two antigen binding domains
[资源] 所有的看家基因(housekeeping genes)列表+引物设计服务
IV isoform 1 (COX4I1), nuclear gene encoding mitochondrial protein, mRNA 2738 NM_004890 Homo sapiens sperm associated antigen 7 (SPAG7), mRNA 618 NM_002812 Homo sapiens proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 (PSMD8), mRNA 942
打破 CAR-T 疗法僵局!过表达 c-JUN 可缓解 T 细胞耗竭,增强 CAR-T 抗肿瘤疗效,并产生实体瘤治疗效果
嵌合抗原受体 T 细胞免疫疗法(Chimeric Antigen Receptor T-Cell Immunotherapy, CAR-T),是近年来发展迅速的细胞治疗技术,可特异性识别肿瘤相关抗原,使效应 T 细胞具有更高的靶向性、杀伤性和持久性,并可克服肿瘤局部免疫抑制微环境,并打破宿主免疫耐受状态。虽然 CAR-T 在实体瘤中疗效不佳,但在肿瘤治疗领域仍具广泛前景。然而,因 T 细胞耗竭导致 CAR-T 细胞功能障碍,严重地阻碍了 CAR-T 治疗的进展。2019 年 12 月 4 日
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