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SRF/SRF蛋白Recombinant Human Ser

um response factor (SRF)重组蛋白c fos serum response element binding factor蛋白
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  • CSB-YP022659HU
  • 2025年07月15日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 保存条件

      Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

    • 保质期

      Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.

    • 英文名

      Recombinant Human Serum response factor (SRF)

    • 库存

      200

    • 供应商

      武汉华美生物工程有限公司

    • 规格

      1mg/100μg/20μg

    规格:1mg产品价格:¥17754.0
    规格:100μg产品价格:¥4164.0
    规格:20μg产品价格:¥2208.0

    纯度:

    Greater than 85% as determined by SDS-PAGE.

    基因名:

    SRF

    Uniprot No.:

    P11831

    别名:

    c fos serum response element binding factor; c fos serum response element binding transcription factor; ELK3; ERP; MCM 1; MCM1; OTTHUMP00000039820; SAP2; Serum response factor; SRF; SRF serum response factor c fos serum response element binding transcription factor; SRF_HUMAN

    种属:

    Homo sapiens (Human)

    蛋白长度:

    Full Length

    来源:

    Yeast

    分子量:

    53.6 kDa

    表达区域:

    1-508aa

    氨基酸序列:

    MLPTQAGAAAALGRGSALGGSLNRTPTGRPGGGGGTRGANGGRVPGNGAGLGPGRLEREAAAAAATTPAPTAGALYSGSEGDSESGEEEELGAERRGLKRSLSEMEIGMVVGGPEASAAATGGYGPVSGAVSGAKPGKKTRGRVKIKMEFIDNKLRRYTTFSKRKTGIMKKAYELSTLTGTQVLLLVASETGHVYTFATRKLQPMITSETGKALIQTCLNSPDSPPRSDPTTDQRMSATGFEETDLTYQVSESDSSGETKDTLKPAFTVTNLPGTTSTIQTAPSTSTTMQVSSGPSFPITNYLAPVSASVSPSAVSSANGTVLKSTGSGPVSSGGLMQLPTSFTLMPGGAVAQQVPVQAIQVHQAPQQASPSRDSSTDLTQTSSSGTVTLPATIMTSSVPTTVGGHMMYPSPHAVMYAPTSGLGDGSLTVLNAFSQAPSTMQVSHSQVQEPGGVPQVFLTASSGTVQIPVSAVQLHQMAVIGQQAG_S_SSNLTELQVVNLDTAHSTKSE

    蛋白标签:

    N-terminal 6xHis-tagged

    产品提供形式:

    Liquid or Lyophilized powder

    缓冲液:

    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

    货期:

    3-7 business days

    注意事项:

    Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.

    功能:

    SRF is a transcription factor that binds to the serum response element (SRE), a short sequence of dyad symmetry located 300 bp to the 5' of the site of transcription initiation of some genes (such as FOS). Required for cardiac differentiation and maturation.

    内毒素:

    Not test.

    SDS-PAGE:

    (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

    LC-MS Image Description/Western Blot:

    /

    Product types:

    In Stock Protein

    Biological_Activity:

    /

    Research Areas:

    Cardiovascular

    Reconstitution:

    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.

    Reference:

    "Identification of multiple SRF N-terminal phosphorylation sites affecting DNA binding properties." Janknecht R., Hipskind R.A., Houthaeve T., Nordheim A., Stunnenberg H.G. EMBO J. 11:1045-1054(1992)

    Function:

    SRF is a transcription factor that binds to the serum response element (SRE), a short sequence of dyad symmetry located 300 bp to the 5' of the site of transcription initiation of some genes (such as FOS). Required for cardiac differentiation and maturation.

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    图标文献和实验
    该产品被引用文献
    "Identification of multiple SRF N-terminal phosphorylation sites affecting DNA binding properties." Janknecht R., Hipskind R.A., Houthaeve T., Nordheim A., Stunnenberg H.G. EMBO J. 11:1045-1054(1992)
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      胶质细胞祖细胞(OPCs)的增殖和分化,并调节成熟少突胶质细胞的髓磷脂可塑性。 为了更深入地了解年轻的脑脊液在 OPCs 中诱导中的作用,他们对用年轻人脑脊液(YH-CSF)处理后的 OPCs 进行转录组学和代谢组学的分析。发现血清反应因子(Serum Response Factor, SRF)显著上调,SRF 可以通过调节肌动蛋白细胞骨架等来诱导细胞运动、增殖和分化。此外,他们还注意到 Wnt 信号负调控因子、促凋亡因子 Bcl7b 和 DNA 修复蛋白 Rpa3 的显著下调。 接下来,为了检测

    • 逆转大脑衰老!Nature:年轻大脑中的神奇蛋白,可提高记忆力,让衰老大脑「重返青春」

      )的增殖和分化,并调节成熟少突胶质细胞的髓磷脂可塑性。 为了更深入地了解年轻的脑脊液在 OPCs 中诱导中的作用,他们对用年轻人脑脊液(YH-CSF)处理后的 OPCs 进行转录组学和代谢组学的分析。发现血清反应因子(Serum Response Factor, SRF)显著上调,SRF 可以通过调节肌动蛋白细胞骨架等来诱导细胞运动、增殖和分化。此外,他们还注意到 Wnt 信号负调控因子、促凋亡因子 Bcl7b 和 DNA 修复蛋白 Rpa3 的显著下调。 接下来,为了检测测试 CSF 诱导

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    文献支持
    SRF/SRF蛋白Recombinant Human Serum response factor (SRF)重组蛋白c fos serum response element binding factor蛋白
    ¥2208 - 17754