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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
human factor B (C3 Proactivator) AAK30167
- 形态:
Liquid
- 保存条件:
Store at 2-8°C.
- 克隆性:
Polyclonal
- 适应物种:
Human factor B (C3 Proactivator)
- 级别:
分子生物学级
- 供应商:
Agrisera
- 宿主:
Goat
- 应用范围:
The optimal working dilution should be determined by the investigator.
- 靶点:
Factor B can be found in normal human serum, where it circulates as a single chain polypeptide. It is a component of the alternative pathway of complement activation.
- 抗体英文名:
Affinity purified using solid phase human Factor B (C3 proactivator). Antibody concentration is > 4.5 mg/ml (E 1% at 280 nm = 13.0).Antibody is supplied in 10 mM sodium phosphate, 0.15 M sodium chloride, pH 7.2. Contains 0.05% (w/v) sodium azide as preser
- 抗体名:
Factor B (C3 Proactivator) (goat antibody)
- 规格:
1 mg
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文献和实验Activation of Nuclear Factor-B
Nuclear factor-κB (NF-κB) is a key transcription factor that regulates the expression of genes involved in immune and inflammatory responses and in cell death and survival. This chapter describes in detail the method for measuring the NF-κB
补体成分 C3(C3a/C3b) 补体成分:C3 血清浓度(μg/ml):550-1200 分子量(kDa):195 亚单位(链)及分子量(kDa):α∶110;β∶85 激活产物:C3a;C3b 生物学活性:C3a 过敏毒素、趋化作用等。 C3b 组成CP、AP中的C3、C5转化
的或自身的)。通过上述转酯反应而获得结合活性的C3b可与c 4b2a结合形成经典途径的C5转化酶(C4b2a3b),或与Bb结合形成替代途径的C3转化酶(C3bBb)和C5转化酶(C 3bnBbC3b也可在H因子和I因子的作用下,变为无活性的C3bi,并再I因子裂解为C3dg和C3c(图5-8)。C3d可能是C3裂解的最终产物,只有在细菌或炎灶分解产物的作用下,才能裂解为C3d和C3c。还报道有C3e片段,可能来源于C3c。 C3各个裂解片段的生物学活性不一。C3a为过敏毒素,能直接作用于肥大
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