m-PEG21-acid

Anti-PEG IgM Production via a PEGylated Nano-Carrier System for Nucleic Acid Delivery

lipoplexes with nucleic acids has significant promise as an efficient delivery system in gene therapy. To achieve in vivo stability and long circulation, most lipoplexes are modified with PEG (PEGylation). However, we reported that PEGylated liposomes lose

Crystallization of Kinesin Family Motor Proteins

MgCl2, 2 mM DTT was pre-incubated with 4 mM AMP*PNP or ATP for 2 hoursCrystals grew in 11% PEG 8000, 0.8 M NaCl, 50 mM Na2H2PO4, pH 6.8, 7 mM DTTYun et al., 2003Rat Kinesin-1 rK354Hanging drop Room temperature9-14 mg/ml protein 20 mM PIPES pH 7.5, 50 mM

健康的减肥药真的要来了？降体重、消炎症，还能改善代谢健康，或成为减肥者福音！

迁移、免疫调节和免疫效应反应等。 这些发现反映了 ARG2 过表达后的肝脏出现了能量消耗增加和抗炎表型。此外，这些肝脏代谢和炎症的改善与诱导产生的 LC3B-II 和 FGF21 蛋白在肝脏和血清中的积累有关，后两者为肝细胞禁食和应激反应的生物标志物。 图片来源：Cell Reports Medicine 药物介导的精氨酸分解代谢可诱导糖尿病小鼠产热和胰岛素耐受 上述的实验证明，肝细胞特异性 arcA 表达可显著改善遗传性糖尿病小鼠的胰岛素抵抗、糖耐受性和血脂异常。ADI-PEG