D，L-赤型-C20-二氢鞘氨醇|D,L-erythro-C

D，L-赤型-C20-二氢鞘氨醇，D,L-erythro-C20-Dihydrosphingosine，D,L-erythro-C20-Dihydrosphingosine

产品名称：D，L-赤型-C20-二氢鞘氨醇-D,L-erythro-C20-Dihydrosphingosine

产品货号：1839-10

产品规格：10mg

背景资料：This product contains both the natural D-erythro isomer and the non-natural L-erythro isomer of dihydrosphingosine. C20 sphingoid bases are common in many organisms and are usually the second most abundant after the C18 sphingoid base. In Saccharomyces cerevisiae it has been found that the amount of C20 dihydrosphingosine increases by 100 fold following heat stress, indicating that it is involved in the signaling of heat stress response.1 Sphinganine (dihydrosphingosine) is the precursor of dihydroceramide which is then desaturated to form ceramide. It is a critical intermediate in the synthesis of many complex sphingoid bases and ceramide analogs. It has been found that sphinganine can induce cell death in a number of types of malignant cells and is being tested for its pharmacological properties.2 Inhibition of dihydroceramide synthesis by some fungal toxins that have a similar structure causes an increase in sphinganine and sphinganine-1-phosphate and a decrease in other sphingolipids leading to a number of diseases including oesophageal cancer.3 Sphinganine has been found to mediate fumonisin (a toxic sphinganine analog) induced hypotension.4 In yeast the amount of C20-dihydrosphingosine increases as a response to heat stress along with other sphingolipids, indicating that it is involved in heat stress adaptation.

保存建议：D，L-赤型-C20-二氢鞘氨醇-D,L-erythro-C20-Dihydrosphingosine对于本产品，我们推荐使用-20℃蓝冰低温进行运输。在您收到货物后，我们建议在-20℃温度下冷冻保存，溶解使用说明请参考本品说明。

产品描述：D,L-erythro-Sphinganine, C20 chain

点击：D，L-赤型-C20-二氢鞘氨醇-D,L-erythro-C20-Dihydrosphingosine查看更详细产品说明，更多应用、储存、价格、货期等信息请致电垂询艾美捷科技有限公司。更多Matreya公司特色试剂盒、特色抗体以及特色试剂等产品评论，请点击查看艾美捷特色产品中心。

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