N-（R，S）-α-羟基十二烷酰基-D-赤型-二氢鞘氨醇|N

N-（R，S）-α-羟基十二烷酰基-D-赤型-二氢鞘氨醇，N-(R,S)-alpha-Hydroxydodecanoyl-D-erythro-dihydrosphingosine，Hydroxydodecanoyl

产品名称：N-（R，S）-α-羟基十二烷酰基-D-赤型-二氢鞘氨醇-N-(R,S)-alpha-Hydroxydodecanoyl-D-erythro-dihydrosphingosine

产品货号：2043-5

产品规格：5mg

背景资料：This product is a high purity alpha-hydroxydihydroceramide and is ideal as a standard and for biological studies. Dihydroceramide is a critical intermediate in the synthesis of many complex sphingoid bases. Inhibition of dihydroceramide synthesis by some fungal toxins that have a similar structure causes an increase in sphinganine and sphinganine-1-phosphate and a decrease in other sphingolipids leading to a number of diseases including oesophageal cancer. Dihydroceramide, synthesized by the acylation of sphinganine, is subsequently converted into ceramide via a desaturase enzyme or into phytosphingosine via the C4-hydrozylase enzyme.1 The presence of a hydroxyl group on the fatty acyl chain of dihydroceramides significantly affects the function and properties of the molecule. While 2(S)-hydroxydihydroceramides can be converted to non-hydroxydihydroceramides in vivo 2(R)-hydroxydihydroceramides cannot. Data presented suggests that 2(R)-hydroxydihydroceramides may interact with some distinct cellular regulatory targets in a specific and more effective manner than their nonhydroxylated analogs.2 2-hydroxydihydroceramides have been shown to be incorporated into the galactosylceramides and sulfatides of the myelin where they are essential to neuronal functions.3

保存建议：N-（R，S）-α-羟基十二烷酰基-D-赤型-二氢鞘氨醇-N-(R,S)-alpha-Hydroxydodecanoyl-D-erythro-dihydrosphingosine对于本产品，我们推荐使用-20℃蓝冰低温进行运输。在您收到货物后，我们建议在-20℃温度下冷冻保存，溶解使用说明请参考本品说明。

产品描述：N-(R,S)-alpha-Hydroxy-C12:0-D-erythro-dihydroceramide

点击：N-（R，S）-α-羟基十二烷酰基-D-赤型-二氢鞘氨醇-N-(R,S)-alpha-Hydroxydodecanoyl-D-erythro-dihydrosphingosine查看更详细产品说明，更多应用、储存、价格、货期等信息请致电垂询艾美捷科技有限公司。更多Matreya公司特色试剂盒、特色抗体以及特色试剂等产品评论，请点击查看艾美捷特色产品中心。

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