N-三癸酰基神经酰胺三己糖|N-Tricosanoyl ce

N-三癸酰基神经酰胺三己糖，N-Tricosanoyl ceramide trihexoside，N-Tricosanoyl ceramide trihexoside

产品名称：N-三癸酰基神经酰胺三己糖-N-Tricosanoyl ceramide trihexoside

产品货号：1524-500

产品规格：500ug

背景资料：This product is a well-defined ceramide trihexoside containing a tricosanoic fatty acid acyl group on the sphingosine. Ceramide trihexoside is a glycosphingolipid found mostly in mammalian cell membranes. It is involved in cellular signaling and has been identified as a receptor for various toxins including shiga toxins and shiga-like toxins.1 Some toxins, such as veratoxins from Escherichia coli, require specific fatty acids on the ceramide portion of CTH to show affinity in binding. An accumulation of CTH in the cellular membranes due to a lack of alpha-galactosidase to convert it into lactosyl ceramide results in Fabry disease.2 This product can be used as an excellent standard for the identification of CTH in Fabry disease by HPLC3 and mass spectrometry.4 An inability to convert CTH to globoside due to mutations in the gene sequence leads to the Pk Blood Group Phenotype. It appears that under certain conditions CTH can enhance anticoagulant activity. CTH has also been studied as a tool to investigate lymphocyte activation.5

保存建议：N-三癸酰基神经酰胺三己糖-N-Tricosanoyl ceramide trihexoside对于本产品，我们推荐使用-20℃蓝冰低温进行运输。在您收到货物后，我们建议在-20℃温度下冷冻保存，溶解使用说明请参考本品说明。

产品描述：N-C23:0-Ceramide trihexoside|N-Tricosanoyl globotriaosylceramide

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