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- 技术资料
- 保存条件:
4°C, protect from light
- 库存:
货期:1-2天
- 供应商:
MedChemExpress LLC
- CAS号:
85030-56-4
- 规格:
100 mg/250 mg/500 mg/1 g/5 g
| 规格: | 100 mg | 产品价格: | ¥100.0 |
|---|---|---|---|
| 规格: | 250 mg | 产品价格: | ¥156.0 |
| 规格: | 500 mg | 产品价格: | ¥265.0 |
| 规格: | 1 g | 产品价格: | ¥434.0 |
| 规格: | 5 g | 产品价格: | ¥1702.0 |
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m-PEG4-Amine
CAS No. : 85030-56-4
MCE 国际站:m-PEG4-Amine
产品活性:m-PEG4-Amine 是一种 PROTAC 连接桥,属于 PEG 类。m-PEG4-Amine 可用于合成一系列 PROTAC 分子。m-PEG4-Amine 是一种可降解 (cleavable) 的 ADC 连接桥,用于抗体活性分子结合物 (ADCs) 的合成。
研究领域:Antibody-drug Conjugate/ADC Related | PROTAC
作用靶点:ADC Linker | PROTAC Linkers
In Vitro: PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
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Trending products:Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Dye Reagents | PROTAC | Isotope-Labeled Compounds
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文献和实验: Add 1 mL of 0.6 M bromoacetic acid (0.6 mmol) in DMF and 86 μL of N,N'-diisopropylcarbodiimide (0.93 equivalent, 0.56 mmol). Incubate with gentle bubbling for 30 minutes, then drain and rinse with 2 mL of DMF (repeat 4x). 6)
-8878.3. Takayama, H. et al. 2008. High-level expression, single-step immunoaffinity purification and characterization of human tetraspanin membrane protein CD81. PLoS ONE 3: e2314 (DOI: 10.1371/journal.pone.0002314).4. Zhong, M. and Molday, R.S. 2010
In Situ Proximity Ligation Assay for Microscopy and Flow Cytometry
interactions. It also includes information on expected results and information on how to troubleshoot the assay. Curr. Protoc. Cytom. 56:9.36.1?9.36.15. © 2011 by John Wiley & Sons, Inc. Keywords: in situ; proximity ligation; protein
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