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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
Pure form: -20°C, 3 years.In solvent: -80°C, 6 months; -20°C, 1 month.
- 库存：
货期：1-2天
- 供应商：
MedChemExpress LLC
- CAS号：
2221949-02-4
- 规格：
25 mg/50 mg/100 mg
| 规格： | 25 mg | 产品价格： | ￥350.0 |
|---|---|---|---|
| 规格： | 50 mg | 产品价格： | ￥560.0 |
| 规格： | 100 mg | 产品价格： | ￥900.0 |
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Bis-PEG10-NHS ester
CAS No. : 2221949-02-4
MCE 国际站：Bis-PEG10-NHS ester
产品活性：Bis-PEG10-NHS ester 是一种 PROTAC 连接桥，属于 PEG 类和 Alkyl/ether 类。Bis-PEG10-NHS ester 可用于合成一系列 PROTAC 分子。Bis-PEG10-NHS ester 是一种可降解 (cleavable) 的 ADC 连接桥，用于抗体活性分子结合物 (ADCs) 的合成。
研究领域：PROTAC | Antibody-drug Conjugate/ADC Related
作用靶点：PROTAC Linkers | ADC Linker
In Vitro: PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
相关产品：5-Ethynyl-2'-deoxyuridine | DSS Crosslinker | Mc-Val-Cit-PABC-PNP | TGN-020 | NH2-C2-NH-Boc | SMCC | DBCO-NHS ester | Sulfo-SMCC sodium | MC-Val-Cit-PAB | DBCO-PEG4-NHS ester | L-Azidohomoalanine hydrochloride | N-Boc-piperazine | DSG Crosslinker | DSP Crosslinker | Val-cit-PAB-OH | Fmoc-3VVD-OH | 3-Mercaptopropionic acid NHS ester | Alkynyl Palmitic Acid | Boc-NH-PEG3 | Amino-PEG3-C2-Azido | Biotin-PEG3-azide | SPDP | Fmoc-Val-Cit-PAB | MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH | Fmoc-8-amino-3,6-dioxaoctanoic acid | Fmoc-Val-Cit-PAB-PNP | MAC glucuronide linker-2 | NH2-PEG2-C6-Cl | Maleimide-DOTA | N3-PEG4-C2-NHS ester
热门产品线：重组蛋白 | 化合物库 | 天然产物 | 荧光染料 | PROTAC | 同位素标记物
Trending products：Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Dye Reagents | PROTAC | Isotope-Labeled Compounds
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文献和实验Preparation Of Peptide-KLH Conjugates For Immunization
.(6) For the -SH coupling, warm the other aliquot of KLH to room temp. Add 1/9 th volume of Iodoacetic acid N-hydroxysuccinimide ester at 100mg/ml in DMSO. Make the DMSO stock fresh, and protect the iodoacetamide reagent from light. We make our own IAA-NHS ester
Preparation Of Peptide-KLH Conjugates For Immunization
of KLH to room temp. Add 1/9 th volume of Iodoacetic acid N-hydroxysuccinimide ester at 100mg/ml in DMSO. Make the DMSO stock fresh, and protect the iodoacetamide reagent from light. We make our own IAA-NHS ester, but it can be purchased from Sigma
Labeling Tubulin and Quantifying Labeling Stoichiometry
that are not clear, using DMSO instead of glycerol for the first polymerization step appears to increase the labeling stoichiometry by ~25% for C2CF-SNHS ester. For labeling with rhodamine (tetramethylrhodamine NHS ester) and X-rhodamine, we generally use glycerol
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