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- 文献和实验
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- 保存条件:
Powder: -20°C, 3 years; 4°C, 2 years.In solvent: -80°C, 6 months; -20°C, 1 month.
- 库存:
货期:1-2天
- 供应商:
MedChemExpress LLC
- CAS号:
40312-34-3
- 规格:
10 mM * 1 mL/1 mg/5 mg
| 规格: | 10 mM * 1 mL | 产品价格: | ¥4767.0 |
|---|---|---|---|
| 规格: | 1 mg | 产品价格: | ¥1485.0 |
| 规格: | 5 mg | 产品价格: | ¥3900.0 |
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Adenosine A1 receptor activator T62
CAS No. : 40312-34-3
MCE 国际站:Adenosine A1 receptor activator T62
产品活性:Adenosine A1 receptor activator T62 是腺苷 A1 受体 (adenosine A1 receptor) 的变构增强剂。Adenosine A1 receptor activator T62 在急性疼痛的动物模型中产生抗伤害感受,并在炎性和神经损伤性疼痛的模型中降低超敏反应。
研究领域:GPCR/G Protein
作用靶点:Adenosine Receptor
In Vivo: Adenosine A1 receptor activator T62 (0.3-3 μg; intrathecal administration; male SpragueDawley rats) treatment produces a dose-dependent antihypersensitivity effect, with no effect on ambulation or activity level.
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文献和实验Use of Affinity Chromatography in Purification of A1 Adenosine Receptors from Rat Brain Membranes
Purification of receptor proteins has always been an important and challenging task in advancing the structural characterization and also in providing sequence data for the molecular cloning of the recep- tors. Some of the difficulties
Characterization of P1 (Adenosine) Purinoceptors
adenosine (ADO) is an important modulator of cellular function in mammalian tissues, modulating cellular function and neuronal excitability via interactions with different cell surface receptor subtypes that are heterogeneously distributed
Overview of Receptor Allosterism
of the binding of the agonist, [3 H] N6 ‐cyclohexyladenosine ([3 H]CHA) by the modulator PD 81,723 at the A1 adenosine receptor in rat brain membranes. Data taken from Bruns and Fergus (). (C ) Simulations based on a model of concomitant orthosteric
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