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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
Powder: -20°C, 3 years.In solvent: -80°C, 6 months; -20°C, 1 month.
- 库存：
货期：1-2天
- 供应商：
MedChemExpress LLC
- CAS号：
1643958-89-7
- 规格：
10 mM * 1 mL/1 mg/5 mg/10 mg/25 mg
| 规格： | 10 mM * 1 mL | 产品价格： | ￥1650.0 |
|---|---|---|---|
| 规格： | 1 mg | 产品价格： | ￥681.0 |
| 规格： | 5 mg | 产品价格： | ￥1500.0 |
| 规格： | 10 mg | 产品价格： | ￥2500.0 |
| 规格： | 25 mg | 产品价格： | ￥5500.0 |
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PDK1-IN-RS2
CAS No. : 1643958-89-7
MCE 国际站：PDK1-IN-RS2
产品活性：PDK1-IN-RS2 是一种肽对接基序 (PIFtide) 的模拟物，也是一种底物选择性 PDK1 抑制剂，Kd 为 9 μM。PDK1-IN-RS2 抑制 PDK1 对下游激酶 S6K1 的激活。
研究领域：PI3K/Akt/mTOR
作用靶点：PDK-1
In Vitro: PDK1-IN-RS2 stimulates the catalytic activity of PDK1 toward a peptide substrate by sixfold. The sulfonyl group of PDK1-IN-RS2 interacts with Arg131 through a salt bridge, because the sulfonamide is likely ionized under the crystallization conditions.
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文献和实验EIJLkNxPtWFZEICIQEYgI7NcIpFqkQZVJQ0mq0nFDx9s3/vF/2P/z6U/ZETOPtClTp0hrO9s+8pGP2rSpk+UpQhpmGStnxAYr/XIZJ1dp79IktsUi1tMU94jDDrWnHn/c5p8zT6S5w00y2js7ZBN8rC/GcczRs+zQQ6ZaZ2entbZ2WktHp1y4VeyS977PdvZsVpqCySmGdaTbpe3dIV/JVblZ89U9RGClbW7v0Ep
instruments (Roboz, cat. no. RS‐9910) 2 Curved microdissecting forceps (Roboz, cat. no. RS‐5135) 1 Operating scissors (Roboz
): 14863-8. 35• Erb RS, Michaels GS. 1999. Linear Modeling of mRNA Expression Levels During CNS Development and Injury ， Pacific Symposium on Biocomputing ， 4: 53-64. 36• Fayyad UM, Piatetsky-shapiro G, Smyth P. 1996. Advances in knowledge discovery
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