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活性氧检测试剂盒

价格￥396 - 1542

品牌碧云天（beyotime）
货号S0033
更新日期2025年09月01日

上海碧云天生物技术股份有限公司

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详细信息
询价记录
文献和实验
技术资料

保存条件：
-20℃
供应商：
上海碧云天生物技术有限公司
规格：
>100次/>500次

规格：	>100次	产品价格：	￥396.0
规格：	>500次	产品价格：	￥1542.0

产品编号	产品名称	产品包装	产品价格
S0033S	活性氧检测试剂盒	>100次	396.00元
S0033M	活性氧检测试剂盒	>500次	1488.00元

活性氧检测试剂盒(Reactive Oxygen Species Assay Kit，也称ROS Assay Kit)是一种利用荧光探针DCFH-DA进行活性氧检测的试剂盒。DCFH-DA本身没有荧光，可以自由穿过细胞膜，进入细胞内后，可以被细胞内的酯酶水解生成DCFH。而DCFH不能通透细胞膜，从而使探针很容易被装载到细胞内。细胞内的活性氧可以氧化无荧光的DCFH生成有荧光的DCF。检测DCF的荧光就可以知道细胞内活性氧的水平。
本试剂盒提供了活性氧阳性对照试剂Rosup，以便于活性氧的检测。Rosup是一种混合物(compound mixture),浓度为50mg/ml。
本试剂盒本底低，灵敏度高，线性范围宽，使用方便。
本试剂盒S0033S包装可以测定100-500个样品，S0033M包装可以测定500-2500个样品。
包装清单：

产品编号	产品名称	包装
S0033S-1	DCFH-DA(10mM)	0.1ml
S0033S-2	活性氧阳性对照(Rosup, 50mg/ml)	1ml
—	说明书	1份

产品编号	产品名称	包装
S0033M-1	DCFH-DA(10mM)	0.5ml
S0033M-2	活性氧阳性对照(Rosup, 50mg/ml)	5ml
—	说明书	1份

保存条件：
-20℃保存，一年有效。
注意事项：
探针装载后，一定要洗净残余的未进入细胞内的探针，否则会导致背景较高。
探针装载完毕并洗净残余探针后，可以进行激发波长的扫描和发射波长的扫描，以确认探针的装载情况是否良好。DCF的激发光谱和发射光谱请参考下页图谱。
尽量缩短探针装载后到测定所用的时间(刺激时间除外)，以减少各种可能的误差。
本产品仅限于专业人员的科学研究用，不得用于临床诊断或治疗，不得用于食品或药品，不得存放于普通住宅内。
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作者 内容 询问日期

文献和实验

该产品被引用文献

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80. Chang Y, Yang ST, Liu JH, Dong E, Wang Y, Cao A, Liu Y, Wang H.

In vitro toxicity evaluation of graphene oxide on A549 cells.

Toxicol Lett. 2011 Feb 5;200(3):201-10. (IF 3.569)

81. Li X, Ye X, Li X, Sun X, Liang Q, Tao L, Kang X, Chen J.

Salidroside protects against MPP(+)-induced apoptosis in PC12 cells by inhibiting the NOpathway.

Brain Res. 2011 Mar 25;1382:9-18. (IF 2.733)

82. Sun L, Guo C, Liu D, Zhao Y, Zhang Y, Song Z, Han H, Chen D, Zhao Y.

Protective effects of bone morphogenetic protein 7 against amyloid-beta inducedneurotoxicity inPC12 cells.

Neuroscience. 2011 Jun 16;184:151-63. (IF 3.056)

83. Zhang Y, Guo J, Zeng L, Zhang J, Hui Y, Liu J, Qing X, Sun X, Guo G.

Tert-butyl-2(4,5-dihydrogen-4,4,5,5-tetramethyl-3-O-1H-imidazole-3-cationic-1-oxyl-2-pyrrolidine-1-carboxylic ester displays novel cytotoxicity through reactive oxygen species-mediated oxidative damage in MCF-7 and MDA-MB-231 cells.

CHEM-BIOL INTERACT. 2011 Jul 15;192(3):287-97. (IF 3.723)

84. Dong E, Wang Y, Yang ST, Yuan Y, Nie H, Chang Y, Wang L, Liu Y, Wang H.

Toxicity of nano gamma alumina to neural stem cells.

J NANOSCI NANOTECHNO. 2011 Sep;11(9):7848-56. (IF 1.134)

85. Liu X, Jin Y, Liu W, Wang F, Hao S.

Possible mechanism of perfluorooctane sulfonate and perfluorooctanoate on the release ofcalcium ion from calcium stores in primary cultures of rat hippocampal neurons.

Toxicol In Vitro. 2011 Oct;25(7):1294-301. (IF 2.959)

86. Li L, Lu N, Dai Q, Wei L, Zhao Q, Li Z, He Q, Dai Y, Guo Q.

GL-V9, a newly synthetic flavonoid derivative, induces mitochondrial-mediated apoptosisandG2/M cell cycle arrest in human hepatocellular carcinoma HepG2 cells.

Eur J Pharmacol. 2011 Nov 16;670(1):13-21. (IF 3.263)

87. Zhang B, Liu ZY, Li YY, Luo Y, Liu ML, Dong HY, Wang YX, Liu Y, Zhao PT, Jin FG, Li ZC.

Antiinflammatory effects of matrine in LPS-induced acute lung injury in mice.

Eur J Pharm Sci. 2011 Dec 18;44(5):573-9. (IF 3.616)

88. Khan M, Yu B, Rasul A, Al Shawi A, Yi F, Yang H, Ma T.

Jaceosidin Induces Apoptosis in U87 Glioblastoma Cells through G2/M Phase Arrest.

EVID-BASED COMPL ALT. 2012;2012:703034. (IF 1.813)

89. Meng FM, Yang JB, Yang CH, Jiang Y, Zhou YF, Yu B, Yang H.

Vitexicarpin Induces Apoptosis in Human Prostate Carcinoma PC-3 Cells through G2/MPhase Arrest.

ASIAN PAC J CANCER P . 2012;13(12):6369-74. (IF 1.24)

90. Cao G, Chen M, Song Q, Liu Y, Xie L, Han Y, Liu Z, Ji Y, Jiang Q.

EGCG protects against UVB-induced apoptosis via oxidative stress and the JNK1/c-Junpathway in ARPE19 cells.

Mol Med Rep. 2012 Jan;5(1):54-9. (IF 2.1)

91. Guo C, He Z, Wen L, Zhu L, Lu Y, Deng S, Yang Y, Wei Q, Yuan H.

Cytoprotective effect of trolox against oxidative damage and apoptosis in the NRK-52ecellsinduced by melamine.

Cell Biol Int. 2012 Feb;36(2):183-8. (IF 2.571)

92. Yu SJ, Liu HC, Ling-Ling E, Wang DS, Zhu GX.

Proliferation and differentiation of osteoblasts from the mandible of osteoporotic rats.

EXP BIOL MED. 2012 Apr;237(4):395-406. (IF 3.139)

93. Wang Y, Wei Y, Zhang H, Shi Y, Li Y, Li R.

Arsenic trioxide induces apoptosis of p53 null osteosarcoma MG63 cells through theinhibition ofcatalase.

Med Oncol. 2012 Jun;29(2):1328-34. (IF 2.834)

94. Zhao D, Lin F, Wu X, Zhao Q, Zhao B, Lin P, Zhang Y, Yu X.

Pseudolaric acid B induces apoptosis via proteasome-mediated Bcl-2 degradation in hormone-refractory prostate cancer DU145 cells.

Toxicol In Vitro. 2012 Jun;26(4):595-602. (IF 2.959)

95. Jia Y, Ji L, Zhang S, Xu L, Yin L, Li L, Zhao Y, Peng J.

Total flavonoids from Rosa Laevigata Michx fruit attenuates hydrogen peroxide inducedinjury inhuman umbilical vein endothelial cells.

Food Chem Toxicol. 2012 Jul 4;50(9):3133-41. (IF 4.679)

96. Guo J, Zhang Y, Zhang J, Liang J, Zeng L, Guo G.

Anticancer effect of tert-butyl-2(4,5-dihydrogen-4,4,5,5-tetramethyl-3-O-1H-imidazole-3-cationic-1-oxyl-2)-pyrrolidine-1-carboxylic ester on human hepatoma HepG2 cell line.

CHEM-BIOL INTERACT. 2012 Jul 30;199(1):38-48. (IF 3.723)

97. Sang H, Zhang L, Li J.

Anti-benzopyrene-7,8-diol-9,10-epoxide induces apoptosis via mitochondrial pathway inhumanbronchiolar epithelium cells independent of the mitochondria permeability transition pore.

Food Chem Toxicol. 2012 Jul;50(7):2417-23. (IF 4.679)

98. Wu C, Shi L, Li Q, Jiang H, Selke M, Yan H, Wang X.

New strategy of efficient inhibition of cancer cells by carborane carboxylicacid-CdTenanocomposites.

Nanomedicine. 2012 Aug;8(6):860-9. (IF 4.717)

99. Zhang JK, Yang L, Meng GL, Fan J, Chen JZ, He QZ, Chen S, Fan JZ, Luo ZJ, Liu J.

Protective effect of tetrahydroxystilbene glucoside against hydrogen peroxide-induceddysfunction and oxidative stress in osteoblastic MC3T3-E1 cells.

Eur J Pharmacol. 2012 Aug 15;689(1-3):31-7. (IF 3.263)

100. Li XY, Jing CQ, Lei WL, Li J, Wang JJ.

Apoptosis caused by imidazolium-based ionic liquids in PC12 cells.

ECOTOX ENVIRON SAFE. 2012 Sep;83:102-7. (IF 4.872)

101. Liu L, Fu J, Li T, Cui R, Ling J, Yu X, Ji H, Zhang Y.

NG, a novel PABA/NO-based oleanolic acid derivative, induces Human hepatoma cell apoptosis viaa ROS/MAPK-dependent mitochondrial pathway.

Eur J Pharmacol. 2012 Sep 15;691(1-3):61-8. (IF 3.263)

102. Zhang X, Liang D, Guo B, Yang L, Wang L, Ma J.

Zinc Inhibits High Glucose-Induced Apoptosis in Peritoneal Mesothelial Cells.

Biol Trace Elem Res. 2012 Dec;150(1-3):424-32. (IF 2.639)

103. Zhang X, Wang J, Fan Y, Yang L, Wang L, Ma J.

Zinc Supplementation Attenuates High Glucose-Induced Epithelial-to-Mesenchymal Transition ofPeritoneal Mesothelial Cells.

Biol Trace Elem Res. 2012 Dec;150(1-3):229-35. (IF 2.639)

104. Jiao L, Wan D, Zhang X, Li B, Zhao H, Liu S.

Characterization and immunostimulating effects on murine peritoneal macrophages ofoligosaccharide isolated from Panax ginseng C.A. Meyer.

J Ethnopharmacol. 2012 Dec 18;144(3):490-6. (IF 3.69)

105. Jiao K, Zhang J, Zhang M, Wei Y, Wu Y, Qiu ZY, He J, Cao Y, Hu J, Zhu H, Niu LN, Cao X, Yang K, Wang MQ.

The identification of CD163 expressing phagocytic chondrocytes in joint cartilage andits novel scavenger role incartilage degradation.

PLoS One. 2013;8(1):e53312. (IF 2.74)

106. Zhang JK, Yang L, Meng GL, Yuan Z, Fan J, Li D, Chen JZ, Shi TY, Hu HM, Wei BY, Luo ZJ, Liu J.

Protection by salidroside against bone loss via inhibition of oxidative stress andbone-resorbing mediators.

PLoS One. 2013;8(2):e57251. (IF 2.74)

107. Ge Y, Weng X, Tian T, Ding F, Huang R, Yuan L, Wu J, Wang T, Guo P, Zhou X.

A mitochondria-targeted zinc(II) phthalocyanine for photodynamic therapy.

RSC Adv. 2013;3:12839-46. (IF 3.119)

108. Wang Z, Ni J, Shao D, Liu J, Shen Y, Zhou L, Huang Y, Yu C, Wang J, Xue H, Lu L.

Elevated transcriptional co-activator p102 mediates angiotensin II type 1 receptorup-regulation and extracellular matrix overproduction in the high glucose-treated ratglomerular mesangial cells and isolated glomeruli.

Eur J Pharmacol. 2013 Feb 28;702(1-3):208-17. (IF 3.263)

109. Cheng P, Ni Z, Dai X, Wang B, Ding W, Rae Smith A, Xu L, Wu D, He F, Lian J.

The novel BH-3 mimetic apogossypolone induces Beclin-1- and ROS-mediated autophagy in humanhepatocellular carcinoma [corrected] cells.

Cell Death Dis. 2013 Feb 7;4:e489. (IF 6.304)

110. Cui S, Chen H, Qian Z, Chen W, Gu Y.

Folate receptor-mediated tumor-targeted upconversion nanocomplex for photodynamictherapy triggered by near-infrared light.

Biophotonics and Immune Responses VIII. 2013 Feb 21; 85820A.

111. Feng L, Zhu M, Zhang M, Jia X, Cheng X, Ding S, Zhu Q.

Amelioration of compound 4,4'-diphenylmethane-bis(methyl)carbamate on high mobilitygroup box1-mediated inflammation and oxidantstressresponses in human umbilical veinendothelial cells via RAGE/ERK1/2/NF-κB pathway.

INT J IMMUNOPATH PH. 2013 Feb;15(2):206-16. (IF 2.209)

112. Du HF, Yu LJ, Meng YF, Lv HY, Meng J, Song XN, Zhang JQ.

Norcantharidin enhances bortezomib-antimyeloma activity in multiple myeloma cells invitro and in nude mousexenografts.

LEUKEMIA LYMPHOMA. 2013 Mar;54(3):607-18. (IF 2.969)

113. Wang K, Gao F, Ji Y, Liu Y, Dan Z, Yang P, Zhu Y, Li S.

ORFH79 impairs mitochondrial function via interaction with a subunit of electrontransport chain complex III inHonglian cytoplasmic male sterile rice.

New Phytol. 2013 Apr;198(2):408-18. (IF 8.512)

114. Li XH, Chen XJ, Ou WB, Zhang Q, Lv ZR, Zhan Y, Ma L, Huang T, Yan YB, Zhou HM.

Knockdown of creatine kinase B inhibits ovarian cancer progression by decreasingglycolysis.

INT J BIOCHEM CELL B. 2013 May;45(5):979-86. (IF 3.673)

115. Qian C, Wang JQ, Song CL, Wang LL, Ji LN, Chao H.

The induction of mitochondria-mediated apoptosis in cancer cells by ruthenium(ii) asymmetric complexes.

Metallomics. 2013 Jun 27;5(7):844-54. (IF 3.796)

116. Chen G, Zhang P, Huang T, Yu W, Lin J, Li P, Chen K.

Polysaccharides from Rhizopus nigricans mycelia induced apoptosis and G2/M arrest inBGC-823 cells.

Carbohydrate Polymers. 2013 Sep 12; 97(2):800-8. (IF 6.044)

117. Ni Z, Dai X, Wang B, Ding W, Cheng P, Xu L, Lian J, He F.

Natural Bcl-2 inhibitor (-)- gossypol induces protective autophagy via reactive oxygenspecies-high mobility groupbox 1 pathway in Burkitt lymphoma.

LEUKEMIA LYMPHOMA. 2013 Oct;54(10):2263-8. (IF 2.969)

118. Liu Y, Dai C, Gao R, Li J.

Ascorbic acid protects against colistin sulfate-induced neurotoxicity in PC12 cells.

TOXICOL MECH METHOD. 2013 Oct;23(8):584-90. (IF 2.295)

119. Wang A, Pu K, Dong B, Liu Y, Zhang L, Zhang Z, Duan W, Zhu Y.

Role of surface charge and oxidative stress in cytotoxicity and genotoxicity of graphene oxide towards humanlung fibroblast cells.

J Appl Toxicol. 2013 Oct;33(10):1156-64. (IF 2.997)

120. Zhong X, Lin R, Li Z, Mao J, Chen L.

Effects of Salidroside on cobalt chloride-induced hypoxia damage and mTOR signalingrepression in PC12 cells.

Biol Pharm Bull. 2014;37(7):1199-206. (IF 1.863)

121. Cheng Y, Feng Y, Zhu M, Yan B, Fu S, Guo J, Hu J, Song X, Guo S, Liu G.

Synthetic liver X receptor agonist T0901317 attenuates high glucose-induced oxidativestress, mitochondrial damage and apoptosis in cardiomyocytes.

Acta Histochem. 2014 Jan;116(1):214-21. (IF 2.107)

122. Lu W, Fu Z, Wang H, Feng J, Wei J, Guo J.

Peroxiredoxin 2 is upregulated in colorectal cancer and contributes to colorectalcancer cells' survival by protecting cells from oxidative stress.

Mol Cell Biochem. 2014 Feb;387(1-2):261-70. (IF 2.795)

123. Wan X, Meng J, Dai Y, Zhang Y, Yan S.

Visualization of network target crosstalk optimizes drug synergism in myocardialischemia.

PLoS One. 2014 Feb 5;9(2):e88137. (IF 2.74)

124. Zheng S, Liu J, Han Q, Huang S, Su W, Fu J, Jia X, Du S, Zhou Y, Zhang X, Guan Y.

Metformin induces renal medullary interstitial cell apoptosis in type 2 diabetic mice.

J Diabetes. 2014 Mar;6(2):132-46. (IF 3.28)

125. He X, Song W, Liu C, Chen S, Hua J.

Rapamycin inhibits acrolein-induced apoptosis by alleviating ROS-driven mitochondrialdysfunction in male germ cells.

CELL PROLIFERAT. 2014 Apr;47(2):161-71. (IF 5.753)

126. Pan B, Yang L, Wang J, Wang Y, Wang J, Zhou X, Yin X, Zhang Z, Zhao D.

C-Abl tyrosine kinase mediates neurotoxic prion peptide-induced neuronal apoptosis viaregulating mitochondrial homeostasis.

Mol Neurobiol. 2014 Apr;49(2):1102-16. (IF 4.5)

127. Yu X, Wang H, Liu L.

Two non-exclusive strategies employed to protect Torulopsis glabrata againsthyperosmotic stress.

APPL MICROBIOL BIOT. 2014 Apr;98(7):3099-110. (IF 3.53)

128. Xu J, Meng K, Zhang R, Yang H, Liao C, Zhu W, Jiao J.

The use of functional chemical-protein associations to identify multi-pathway renoprotectants.

PLoS One. 2014 May 15;9(5):e97906. (IF 2.74)

129. Zheng W, Li Y, Du J, Yin Z.

Fabrication of biocompatible and tumor-targeting hyaluronan nanospheres by a modifieddesolvation method.

EUR J PHARM SCI. 2014 May;103(5):1529-37. (IF 3.616)

130. Zhao J, Wu Y, Alfred AT, Wei P, Yang S.

Anticancer effects of pyocyanin on HepG2 human hepatoma cells.

Lett Appl Microbiol. 2014 Jun;58(6):541-8. (IF 2.173)

131. Zhong L, Wang Y, Li W, Gu J, Li X, Wang X, Yue Z, Mu Y, Bai J, Li R, Zhang H.

Heme oxygenase-1 silencing increases the sensitivity of human osteosarcoma MG63 cells toarsenic trioxide.

Mol Cell Biochem. 2014 Jul;392(1-2):135-44. (IF 2.795)

132. Xu SY, Hu YF, Li WP, Wu YM, Ji Z, Wang SN, Li K, Pan SY.

Intermittent hypothermia is neuroprotective in an in vitro model of ischemic stroke.

Int J Biol Sci. 2014 Jul 29;10(8):873-81. (IF 4.858)

133. Shen C, Wang S, Shan Y, Liu Z, Fan F, Tao L, Liu Y, Zhou L, Pei C, Wu H, Tian C, RuanJ, Chen W, Wang A, Zheng S, Lu Y.

Chemomodulatory efficacy of lycopene on antioxidant enzymes and carcinogen-inducedcutaneum carcinoma in mice.

Food Funct. 2014 Jul 25;5(7):1422-31. (IF 4.171)

134. Yuan D, Wan JZ, Deng LL, Zhang CC, Dun YY, Dai YW, Zhou ZY, Liu CQ, Wang T.

Chikusetsu saponin V attenuates MPP+-induced neurotoxicity in SH-SY5Y cells viaregulation of Sirt1/Mn-SOD and GRP78/caspase-12 pathways.

Int J Mol Sci. 2014 Jul 28;15(8):13209-22. (IF 4.556)

135. Zhang J, Xu L, Zhang L, Ying Z, Su W, Wang T.

Curcumin attenuates D-galactosamine/lipopolysaccharide-induced liver injury andmitochondrial dysfunction in mice.

J Nutr. 2014 Aug;144(8):1211-8. (IF 4.281)

136. Jian Z, Li K, Song P, Zhu G, Zhu L, Cui T, Liu B, Tang L, Wang X, Wang G, Gao T, Li C.

Impaired activation of the Nrf2-ARE signaling pathway undermines H2O2-induced oxidativestress response: a possible mechanism for melanocyte degeneration in vitiligo.

J Invest Dermatol. 2014 Aug;134(8):2221-30. (IF 7.143)

137. Yang X, He C, Li J, Chen H, Ma Q, Sui X, Tian S, Ying M, Zhang Q, Luo Y, Zhuang Z, LiuJ.

Uptake of silica nanoparticles: neurotoxicity and Alzheimer-like pathology in humanSK-N-SH and mouse neuro2a neuroblastoma cells.

Toxicol Lett. 2014 Aug 17;229(1):240-9. (IF 3.569)

138. Miao SH, Sun HB, Ye Y, Yang JJ, Shi YW, Lu M, Hu G, Zhou JW.

Astrocytic JWA expression is essential to dopaminergic neuron survival in thepathogenesis of Parkinson's disease.

CNS Neurosci Ther. 2014 Aug;20(8):754-62. (IF 4.074)

139. Ma W, Yuan L, Yu H, Xi Y, Xiao R.

Mitochondrial dysfunction and oxidative damage in the brain of diet-induced obese ratsbut not in diet-resistant rats.

Life Sci. 2014 Aug 21;110(2):53-60. (IF 3.647)

140. Xu T, Pang Q, Zhou D, Zhang A, Luo S, Wang Y, Yan X.

Proteomic investigation into betulinic acid-induced apoptosis of human cervical cancerHeLa cells.

PLoS One. 2014 Aug 22;9(8):e105768. (IF 2.74)

141. Ma Y, Li R, Zhang Y, Zhou L, Dai Y.

Knockdown of peroxiredoxin 5 inhibits the growth of osteoarthritic chondrocytes viaupregulating Wnt/β-catenin signaling.

FREE RADICAL BIO MED. 2014 Sep 16;76C:251-260. (IF 6.17)

142. Zhao JY, Cui R, Zhang ZL, Zhang M, Xie ZX, Pang DW.

Cytotoxicity of nucleus-targeting fluorescent gold nanoclusters.

Nanoscale. 2014 Oct 9;6(21):13126-34. (IF 6.895)

143. Jin Y, Liu K, Peng J, Wang C, Kang L, Chang N, Sun H.

Rhizoma Dioscoreae Nipponicae polysaccharides protect HUVECs from H2O2-induced injuryby regulating PPARγ factor and the NADPH oxidase/ROS-NF-κB signal pathway.

Toxicol Lett. 2014 Oct 8; 232(1):149-158. (IF 3.569)

144. Xie J, Bai X, Li Y, Sun C, Qian H, Fu Z.

The effect of glufosinate on nitrogen assimilation at the physiological, biochemicaland molecular levels in Phaeodactylum tricornutum.

Ecotoxicology. 2014 Oct;23(8):1430-8. (IF 2.535)

145. Chen Y, Zhao S, Wang Y, Li Y, Bai L, Liu R, Fan J, Liu E.

Homocysteine reduces protein S-nitrosylation in endothelium.

Int J Mol Med. 2014 Nov;34(5):1277-85. (IF 3.098)

146. Wang S, Shi N, Geng Z, Li X, Hu X, Wang Z.

Inhibitory mechanism of dimercaptopropanesulfonic acid (DMPS) in the cellularbiomethylation of arsenic.

Biochimie. 2014 Nov;106:167-74. (IF 3.413)

147. Guan G, Han H, Yang Y, Jin Y, Wang X, Liu X.

Neferine prevented hyperglycemia-induced endothelial cell apoptosis through suppressingROS/Akt/NF-κB signal.

Endocrine. 2014 Dec;47(3):764-71. (IF 3.235)

148. Gu M, Xu J, Han C, Kang Y, Liu T, He Y, Huang Y, Liu C.

Effects of Berberine on Cell Cycle, DNA, Reactive Oxygen Species, and Apoptosis in L929 Murine Fibroblast Cells.

EVID-BASED COMPL ALT. 2015;2015:796306. (IF 1.813)

149. Xiong L, Xie J, Song C, Liu J, Zheng J, Liu C, Zhang X, Li P, Wang F.

The Activation of Nrf2 and Its Downstream Regulated Genes Mediates the Antioxidative Activities of Xueshuan Xinmaining Tablet in Human Umbilical Vein Endothelial Cells.

EVID-BASED COMPL ALT. 2015;2015:187265. (IF 1.813)

150. Li Y, Chen K, Zhou Y, Xiao Y, Deng M, Jiang Z, Ye W, Wang X, Wei X, Li J, Liang J, Zheng Z, Yao Y, Wang W, Li P, Xu B.

A New Strategy to Target Acute Myeloid Leukemia Stem and Progenitor Cells Using Chidamide, a Histone Deacetylase Inhibitor.

CURR CANCER DRUG TAR. 2015;15(6):493-503. (IF 2.912)

151. Xiao W, Jiang Y, Men Q, Yuan L, Huang Z, Liu T, Li W, Liu X.

Tetrandrine induces G1/S cell cycle arrest through the ROS/Akt pathway in EOMA cells andinhibits angiogenesis in vivo.

Int J Oncol. 2015 Jan;46(1):360-8. (IF 3.899)

152. Xing Y, Bao W, Fan X, Liu K, Li X, Xi T.

A novel oxaliplatin derivative, Ht-2, triggers mitochondrion-dependent apoptosis inhuman colon cancer cells.

Apoptosis. 2015 Jan;20(1):83-91. (IF 4.543)

153. Hou J, Cui A, Song P, Hua H, Luo T, Jiang Y.

Reactive oxygen species-mediated activation of the Src-epidermal growth factor receptor-Akt signaling cascade prevents bortezomib-induced apoptosis in hepatocellular carcinoma cells.

Mol Med Rep. 2015 Jan;11(1):712-8. (IF 2.1)

154. Lan QY, Liu QL, Cai J, Liu AW.

3-cinnamoyl-4-hydroxy-6-methyl-2H-pyran-2-one (CHP) inhibits human ovarian cell proliferation by inducing apoptosis.

INT J CLIN EXP PATHO. 2015 Jan 1;8(1):155-63. (IF 0.252)

155. Wang X, Yu S, Wang CY, Wang Y, Liu HX, Cui Y, Zhang LD.

Advanced glycation end products induce oxidative stress and mitochondrial dysfunction inSH-SY5Y cells.

IN VITRO CELL DEV-AN. 2015 Feb;51(2):204-9. (IF 1.665)

156. Bai YH, Wang JP, Yang M, Zeng Y, Jiang HY.

SiRNA-HMGA2 weakened AGEs-induced epithelial-to-mesenchymal transition in tubular epithelial cells.

BIOCHEM BIOPH RES CO. 2015 Feb 20;457(4):730-5. (IF 2.985)

157. Shi J, Sun B, Shi W, Zuo H, Cui D, Ni L, Chen J.

Decreasing GSH and increasing ROS in chemosensitivity gliomas with IDH1 mutation.

TUMOR BIOL . 2015 Feb;36(2):655-62. (IF 3.65)

158. Jiang L, Wang L, Chen L, Cai GH, Ren QY, Chen JZ, Shi HJ, Xie YH.

As2O3 induces apoptosis in human hepatocellular carcinoma HepG2 cells through a ROS-mediated mitochondrial pathway and activation of caspases.

Int J Clin Exp Med. 2015 Feb 15;8(2):2190-6. (IF 0.166)

159. Zhan R, Han Q, Zhang C, Tian Z, Zhang J.

Toll-Like receptor 2 (TLR2) and TLR9 play opposing roles in host innate immunity against Salmonella enterica serovar Typhimurium infection.

Infect Immun. 2015 Apr;83(4):1641-9. (IF 3.201)

160. Zhang Q, Cheng G, Qiu H, Zhu L, Ren Z, Zhao W, Zhang T, Liu L.

The p53-inducible gene 3 involved in flavonoid-induced cytotoxicity through the reactive oxygen species-mediated mitochondrial apoptotic pathway in human hepatoma cells.

Food Funct. 2015 May;6(5):1518-25. (IF 4.171)

161. Hua P, Sun M, Zhang G, Zhang Y, Tian X, Li X, Cui R, Zhang X.

Cepharanthine induces apoptosis through reactive oxygen species and mitochondrial dysfunction in human non-small-cell lung cancer cells.

BIOCHEM BIOPH RES CO. 2015 May 1;460(2):136-42. (IF 2.985)

162. Li P, Li Z.

Neuroprotective effect of paeoniflorin on H2O2-induced apoptosis in PC12 cells by modulation of reactive oxygen species and the inflammatory response.

Exp Ther Med. 2015 May;9(5):1768-72. (IF 1.785)

163. Yu S, Hou D, Chen P, Zhang Q, Lv B, Ma Y, Liu F, Liu H, Song EJ, Yang D, Liu J.

Adenosine induces apoptosis through TNFR1/RIPK1/P38 axis in colon cancer cells.

BIOCHEM BIOPH RES CO. 2015 May 8;460(3):759-65. (IF 2.985)

164. Hou W, Gao W, Wang D, Liu Q, Zheng S, Wang Y.

The Protecting Effect of Deoxyschisandrin and Schisandrin B on HaCaT Cells against UVB-Induced Damage.

PLoS One. 2015 May 15;10(5):e0127177. (IF 2.74)

165. Chen P, Hu YF, Wang L, Xiao WF, Bao XY, Pan C, Yi HS, Chen XY, Pan MH, Lu C.

Mitochondrial Apoptotic Pathway Is Activated by H2O2-Mediated Oxidative Stress in BmN-SWU1 Cells from Bombyx mori Ovary.

PLoS One. 2015 Jul 30;10(7):e0134694. (IF 2.74)

166. Yan X, Yang X, Hao X, Ren Q, Gao J, Wang Y, Chang N, Qiu Y, Song G.

Sodium Fluoride Induces Apoptosis in H9c2 Cardiomyocytes by Altering Mitochondrial Membrane Potential and Intracellular ROS Level.

Biol Trace Elem Res. 2015 Aug;166(2):210-5. (IF 2.639)

167. Zhang F, Cui J, Lv B, Yu B.

Nicorandil protects mesenchymal stem cells against hypoxia and serum deprivation-induced apoptosis.

Int J Mol Med. 2015 Aug;36(2):415-23. (IF 3.098)

168. Wang X, Chen L, Wang T, Jiang X, Zhang H, Li P, Lv B, Gao X.

Ginsenoside Rg3 antagonizes adriamycin-induced cardiotoxicity by improving endothelial dysfunction from oxidative stress via upregulating the Nrf2-ARE pathway through the activation of akt.

Phytomedicine. 2015 Sep 15;22(10):875-84. (IF 4.268)

169. Wei X, Zhu X, Hu N, Zhang X, Sun T, Xu J, Bian X.

Baicalin attenuates angiotensin II-induced endothelial dysfunction.

BIOCHEM BIOPH RES CO. 2015 Sep 11;465(1):101-7. (IF 2.985)

170. Qiu M, Chen L, Tan G, Ke L, Zhang S, Chen H, Liu J.

A reactive oxygen species activation mechanism contributes to JS-K-induced apoptosis in human bladder cancer cells.

SCI REP-UK. 2015 Oct 13;5:15104. (IF 3.998)

171. Li Y, Zhu H, Wang S, Qian X, Fan J, Wang Z, Song P, Zhang X, Lu W, Ju D.

Interplay of Oxidative Stress and Autophagy in PAMAM Dendrimers-Induced Neuronal Cell Death.

Theranostics. 2015 Oct 8;5(12):1363-77. (IF 8.579)

172. Song B, Zhang H, Jiang L, Chi Y, Tian J, Du W, Yu B, Han Z.

Down-regulation of lipocalin 2 suppresses the growth of human lung adenocarcinoma through oxidative stress involving Nrf2/HO-1 signaling.

ACTA BIOCH BIOPH SIN. 2015 Oct;47(10):805-14. (IF 2.836)

173. Xue H, Gan F, Zhang Z, Hu J, Chen X, Huang K.

Astragalus polysaccharides inhibits PCV2 replication by inhibiting oxidative stress and blocking NF-κB pathway.

Int J Biol Macromol. 2015 Nov;81:22-30. (IF 5.162)

174. Zhang E, Guo Q, Gao H, Xu R, Teng S, Wu Y.

Metformin and Resveratrol Inhibited High Glucose-Induced Metabolic Memory of Endothelial Senescence through SIRT1/p300/p53/p21 Pathway.

PLoS One. 2015 Dec 2;10(12):e0143814. (IF 2.74)

175. Shen K, Wang Y, Zhang Y, Zhou H, Song Y, Cao Z, Kou J, Yu B.

Cocktail of Four Active Components Derived from Sheng Mai San Inhibits Hydrogen Peroxide-Induced PC12 Cell Apoptosis Linked with the Caspase-3/ROCK1/MLC Pathway.

REJUV RES. 2015 Dec;18(6):517-27. (IF 3.811)

176. Hong Z, Guo Z, Zhang R, Xu J, Dong W, Zhuang G, Deng C.

Airborne Fine Particulate Matter Induces Oxidative Stress and Inflammation in Human Nasal Epithelial Cells.

Tohoku J Exp Med. 2016;239(2):117-25. (IF 1.441)

177. Feng B, Qiu L, Ye C, Chen L, Fu Y, Sun W.

Exposure toa 50-Hz magnetic field induced mitochondrial permeability transition through the ROS/GSK-3βsignaling pathway.

Int J Radiat Biol. 2016;92(3):148-55. (IF 2.368)

178. Tian X, Zhao L, Song X, Yan Y, Liu N, Li T, Yan B, Liu B.

HSP27 Inhibits Homocysteine-Induced Endothelial Apoptosis by Modulation of ROS Production andMitochondrial Caspase-Dependent Apoptotic Pathway.

Biomed Res Int. 2016;2016:4847874. (IF 2.276)

179. Zhang M, Du Y, Lu R, Shu Y, Zhao W, Li Z, Zhang Y, Liu R, Yang T, Luo S, Gao M, Zhang Y, Zhang G, Liu J, Lu Y.

Cholesterol Retards Senescence in BoneMarrow MesenchymalStem Cells by Modulating

Oxid Med Cell Longev. 2016;2016:7524308. (IF 5.076)

180. Cao LJ, Li HD, Yan M, Li ZH, Gong H, Jiang P, Deng Y, Fang PF, Zhang BK.

The Protective Effects of Isoliquiritigenin and Glycyrrhetinic Acid against Triptolide-Induced OxidativeStress in HepG2 Cells Involve Nrf2 Activation.

EVID-BASED COMPL ALT. 2016;2016:8912184. (IF 1.813)

181. Luo D, Ni Q, Ji A, Gu W, Wu J, Jiang C.

Dehydroabietic Acid Derivative QC4 Induces Gastric Cancer Cell Death via Oncosis and Apoptosis.

Biomed Res Int. 2016;2016:2581061. (IF 2.276)

182. Yang F, Yan G, Li Y, Han Z, Zhang L, Chen S, Feng C, Huang Q, Ding F, Yu Y, Bi C, Cai B, Yang L.

Astragalus Polysaccharide Attenuated Iron Overload-Induced Dysfunction of Mesenchymal Stem Cells viaSuppressing Mitochondrial ROS.

CELL PHYSIOL BIOCHEM. 2016;39(4):1369-79. (IF 5.5)

183. Wei C, Wang Y, Li M, Li H, Lu X, Shao H, Xu C.

Spermine inhibits Endoplasmic Reticulum Stress-induced Apoptosis: a New Strategy

CELL PHYSIOL BIOCHEM. 2016;38(2):531-44. (IF 5.5)

184. Yu W, Chen G, Zhang P, Chen K.

Purification, partial characterization and antitumor effect of an exopolysaccharide from Rhizopus nigricans.

Int J Biol Macromol. 2016 Jan;82:299-307. (IF 5.162)

185. Qin M, Lin Z, Wang D, Long X, Zheng M, Qiu Y.

What are the differences between aerobic and anaerobic toxic effects of sulfonamides on Escherichia coli?

ENVIRON TOXICOL CHEM. 2016 Jan;41:251-8. (IF 3.152)

186. Zeng L, Chen Y, Liu J, Huang H, Guan R, Ji L, Chao H.

Ruthenium(II) Complexes with 2-Phenylimidazo[4,5-f][1,10]phenanthroline Derivatives that Strongly CombatCisplatin-Resistant Tumor Cells.

SCI REP-UK. 2016 Jan 14;6:19449. (IF 3.998)

187. Chen C, Cao J, Ma X, Wang X, Chen Q, Yan S, Zhao N, Geng Z, Wang Z.

Neuroprotection by Polynitrogen Manganese Complexes: Regulation of Reactive Oxygen Species-RelatedPathways.

SCI REP-UK. 2016 Feb 9;6:20853. (IF 3.998)

188. Wang Y, Wang H, Qian C, Tang J, Zhou W, Liu X, You Q, Hu R.

3-(2-Oxo-2-phenylethylidene)-2,3,6,7-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4(11bH)-one (compound 1), a novel potent Nrf2/ARE inducer, protects against DSS-induced colitis via inhibiting NLRP3 inflammasome.

Biochem Pharmacol. 2016 Feb 1;101:71-86. (IF 4.96)

189. Li B, Zhang J, Wang Z, Chen S.

Ivabradine Prevents Low Shear Stress Induced Endothelial Inflammation and Oxidative Stress viamTOR/eNOS Pathway.

PLoS One. 2016 Feb 18;11(2):e0149694. (IF 2.74)

190. Kong GM, Tao WH, Diao YL, Fang PH, Wang JJ, Bo P, Qian F.

Melittin induces human gastric cancer cell apoptosis via activation of mitochondrial pathway.

WORLD J GASTROENTERO. 2016 Mar 21;22(11):3186-95. (IF 3.665)

191. Xie D, Wu X, Lan L, Shangguan F, Lin X, Chen F, Xu S, Zhang Y, Chen Z, Huang K, Wang R, Wang L, Song X, Liu Y, Lu B.

Downregulation of TFAM inhibits the tumorigenesis of non-small cell lung cancer by activating ROS-mediated JNK/p38MAPK signaling and reducing cellular bioenergetics.

ONCOTARGET. 2016 Mar 8;7(10):11609-24. (IF 5.168)

192. Zhang X, Wang L, Wang R, Luo X, Li Y, Chen Z.

Protective effects of rice dreg protein hydrolysates against hydrogen peroxide-induced oxidative stress inHepG-2 cells.

Food Funct. 2016 Mar;7(3):1429-37. (IF 4.171)

193. Shu Y, Liu Y, Li X, Cao L, Yuan X, Li W, Cao Q.

Aspirin-Triggered Resolvin D1 Inhibits TGF-β1-Induced EndMT through Increasing the Expression of Smad7and Is Closely Related to Oxidative Stress.

BIOMOL THER. 2016 Mar 1;24(2):132-9. (IF 3.47)

194. Chen H, Lu Y, Cao Z, Ma Q, Pi H, Fang Y, Yu Z, Hu H, Zhou Z.

Cadmium induces NLRP3 inflammasome-dependent pyroptosis in vascular endothelial cells.

Toxicol Lett. 2016 Mar 30;246:7-16. (IF 3.569)

195. Zhang X, Wang Y, Han S, Xiang H, Peng Y, Wu Y, Pan S, Zhang Y, Ruan J.

RY10-4 Inhibits the Proliferation of Human Hepatocellular Cancer HepG2 Cells by Inducing Apoptosis InVitro and In Vivo.

PLoS One. 2016 Mar 14;11(3):e0151679. (IF 2.74)

196. Sun A, Lin J, Pi C, Xu R, Cui X.

Biological Evaluation of Ferrocenyl Olefins: Cancer Cell Growth Inhibition, ROS Production, and ApoptosisActivity.

ARCH PHARM. 2016 Mar;349(3):186-92. (IF 2.59)

197. Jin F, Qiao C, Luan N, Li H.

Lentivirus-mediated PHLDA2 overexpression inhibits trophoblast proliferation, migration and invasion, andinduces apoptosis.

Int J Mol Med. 2016 Apr;37(4):949-57. (IF 3.098)

198. Shang CH, Zhang QQ, Zhou JH.

Oridonin Inhibits Cell Proliferation and Induces Apoptosis in Rheumatoid Arthritis Fibroblast-LikeSynoviocytes.

Inflammation. 2016 Apr;39(2):873-80. (IF 3.212)

199. Liu Z, Zhan X, Yang M, Yang Q, Xu X, Lan F, Wu Y, Gu Z.

A magnetic-dependent protein corona of tailor-made superparamagnetic iron oxides alters their biologicalbehaviors.

Nanoscale. 2016 Apr 14;8(14):7544-55. (IF 6.895)

200. Chen Y, Zhang Y, Ji H, Ji Y, Yang J, Huang J, Sun D.

Involvement of hypoxia-inducible factor-1α in the oxidative stress induced by advanced

Toxicol In Vitro. 2016 Apr;32:146-53. (IF 2.959)

201. Zhang J, Jiang H, Xie L, Hu J, Li L, Yang M, Cheng L, Liu B, Qian X.

Antitumor effect of manumycin on colorectal cancer cells by increasing the reactive oxygen speciesproduction and blocking PI3K-AKT pathway.

ONCOTARGETS THER. 2016 May 24;9:2885-95. (IF 3.337)

202. Wang Y, Zhang S, Zhang C, Zhao Z, Zheng X, Xue L, Liu J, Yuan XC.

Investigation of an SPR biosensor for determining the influence of connexin 43 expression on thecytotoxicity of cisplatin.

Analyst. 2016 May 23;141(11):3411-20. (IF 3.978)

203. Zhang T, Shao Y, Chu TY, Huang HS, Liou YL, Li Q, Zhou H.

MiR-135a and MRP1 play pivotal roles in the selective lethality of phenethyl isothiocyanate to malignantglioma cells.

Am J Cancer Res. 2016 May 1;6(5):957-72. (IF 5.177)

204. Lu MC, Ji JA, Jiang YL, Chen ZY, Yuan ZW, You QD, Jiang ZY.

An inhibitor of the Keap1-Nrf2 protein-protein interaction protects NCM460 colonic

SCI REP-UK. 2016 May 24;6:26585. (IF 3.998)

205. Zhu W, Ma L, Yang B, Zheng Z, Chai R, Liu T, Liu Z, Song T, Li F, Li G.

Flavone inhibits migration through DLC1/RhoA pathway by decreasing ROS generation in breast cancercells.

IN VITRO CELL DEV-AN. 2016 May;52(5):589-97. (IF 1.665)

206. Gao M, Chen G, Wang H, Xie B, Hu L, Kong Y, Yang G, Tao Y, Han Y, Wu X, Zhang Y, Dai B, Shi J.

Therapeutic potential and functional interaction of carfilzomib and vorinostat in T-cell leukemia/lymphoma.

ONCOTARGET. 2016 May 17;7(20):29102-15. (IF 5.168)

207. Liu G, Kuang S, Wu S, Jin W, Sun C.

A novel polysaccharide from Sargassum integerrimum induces apoptosis in A549 cells and preventsangiogensis in vitro and in vivo.

SCI REP-UK. 2016 May 24;6:26722. (IF 3.998)

208. Ma YL, Zhang LX, Liu GL, Fan Y, Peng Y, Hou WG.

N-Myc Downstream-Regulated Gene 2 (Ndrg2) Is Involved in Ischemia-Hypoxia-Induced AstrocyteApoptosis: a Novel Target for Stroke Therapy.

Mol Neurobiol. 2016 May 6.[Epub ahead of print] (IF 4.5)

209. Qiao ZY, Zhao WJ, Cong Y, Zhang D, Hu Z, Duan ZY, Wang H.

Self-Assembled ROS-Sensitive Polymer-Peptide Therapeutics Incorporating Built-in Reporters forEvaluation of Treatment Efficacy.

Biomacromolecules. 2016 May 9;17(5):1643-52. (IF 6.092)

210. Zhou XY, Zhang T, Ren L, Wu JJ, Wang W, Liu JX.

Copper elevated embryonic hemoglobin through reactive oxygen species during zebrafish erythrogenesis.

Aquat Toxicol. 2016 Jun;175:1-11. (IF 4.344)

211. Yin T, Zhang Z, Cao B, Duan Q, Shi P, Zhao H, Camara SN, Shen Q, Wang C.

Bmi1 inhibition enhances the sensitivity of pancreatic cancer cells to gemcitabine.

ONCOTARGET. 2016 Jun 14;7(24):37192-37204. (IF 5.168)

212. Qi L, Lv X, Zhang T, Jia P, Yan R, Li S, Zou R, Xue Y, Dai L.

Cytotoxicity and genotoxicity of bacterial magnetosomes against human retinal pigment epithelium cells.

SCI REP-UK. 2016 Jun 1;6:26961. (IF 3.998)

213. Qin WD, Liu GL, Wang J, Wang H, Zhang JN, Zhang F, Ma Y, Ji XY, Li C, Zhang MX.

Poly(ADP-ribose) polymerase 1 inhibition protects cardiomyocytes from inflammation and apoptosis indiabetic cardiomyopathy.

ONCOTARGET. 2016 Jun 14;7(24):35618-35631. (IF 5.168)

214. Xu C, Liu Q, Liu H, Zhang C, Shao W, Gu A.

Toxicological assessment of multi-walled carbon nanotubes in vitro: potential mitochondria effects on malereproductive cells.

ONCOTARGET. 2016 Jun 28;7(26):39270-39278. (IF 5.168)

215. Li X, Song Y, Zhang P, Zhu H, Chen L, Xiao Y, Xing Y.

Oleanolic acid inhibits cell survival and proliferation of prostate cancer cells in vitro and in vivo through thePI3K/Akt pathway.

TUMOR BIOL . 2016 Jun;37(6):7599-613. (IF 3.65)

216. Zhang X, Liang D, Lian X, Jiang Y, He H, Liang W, Zhao Y, Chi ZH.

Berberine activates Nrf2 nuclear translocation and inhibits apoptosis induced by high glucose in renaltubular epithelial cells through a phosphatidylinositol 3-kinase/Akt-dependent mechanism.

Apoptosis. 2016 Jun;21(6):721-36. (IF 4.543)

217. Wang H, Liang X, Luo G, Ding M, Liang Q.

Protection effect of nicotinamide on cardiomyoblast hypoxia/re-oxygenation injury: study of cellularmitochondrial metabolism.

Mol Biosyst. 2016 Jun 21;12(7):2257-64. (IF 3.336)

218. Ding C, Zhao Y, Shi X, Zhang N, Zu G, Li Z, Zhou J, Gao D, Lv L, Tian X, Yao J.

New insights into salvianolic acid A action: Regulation of the TXNIP/NLRP3 and TXNIP/ChREBP pathwaysameliorates HFD-induced NAFLD in rats.

SCI REP-UK. 2016 Jun 27;6:28734. (IF 3.998)

219. Zhu L, Su Q, Jie X, Liu A, Wang H, He B, Jiang H.

NG2 expression in microglial cells affects the expression of neurotrophic and proinflammatory factors byregulating FAK phosphorylation.

SCI REP-UK. 2016 Jun 16;6:27983. (IF 3.998)

220. Li Q, Zhou M, Fan X, Yan J, Li W, Xie J.

Mycobacteriophage SWU1 gp39 can potentiate multiple antibiotics against Mycobacterium via altering thecell wall permeability.

SCI REP-UK. 2016 Jun 28;6:28701. (IF 3.998)

221. Ding GC, Chen M, Wang YX, Rui C, Xu W, Ding HJ, Shi ZH.

MicroRNA-128a-induced apoptosis in HTR-8/SVneo trophoblast cells contributes to pre-eclampsia.

Biomed Pharmacother. 2016 Jul;81:63-70. (IF 4.545)

222. Yang JB, Khan M, He YY, Yao M, Li YM, Gao HW, Ma TH.

Tubeimoside-1 induces oxidative stress-mediated apoptosis and G0/G1 phase arrest in human prostatecarcinoma cells in vitro.

Acta Pharmacol Sin. 2016 Jul;37(7):950-62. (IF 5.064)

223. Cheong CU, Yeh CS, Hsieh YW, Lee YR, Lin MY, Chen CY, Lee CH.

Protective Effects of Costunolide against Hydrogen Peroxide-Induced Injury in PC12 Cells.

Molecules. 2016 Jul 9;21(7). pii: E898. (IF 3.267)

224. Wang YW, Zhang JH, Yu Y, Yu J, Huang L.

Inhibition of Store-Operated Calcium Entry Protects Endothelial Progenitor Cells from H2O2-InducedApoptosis.

BIOMOL THER. 2016 Jul 1;24(4):371-9. (IF 3.47)

225. Duan X, Huang X, Wang X, Yan S, Guo S, Abdalla AE, Huang C, Xie J.

l-Serine potentiates fluoroquinolone activity against Escherichia coli by enhancing endogenous reactiveoxygen species production.

J ANTIMICROB CHEMOTH. 2016 Aug;71(8):2192-9. (IF 5.439)

226. Liu X, Li J, Peng X, Lv B, Wang P, Zhao X, Yu B.

Geraniin Inhibits LPS-Induced THP-1 Macrophages Switching to M1 Phenotype via SOCS1/NF-κB Pathway.

Inflammation. 2016 Aug;39(4):1421-33. (IF 3.212)

227. Bi C, Jiang Y, Fu T, Hao Y, Zhu X, Lu Y.

Naringin inhibits lipopolysaccharide-induced damage in human umbilical vein endothelial cells viaattenuation of inflammation, apoptosis and MAPK pathways.

Cytotechnology. 2016 Aug;68(4):1473-87. (IF 1.777)

228. Yue L, Wang W, Wang Y, Du T, Shen W, Tang H, Wang Y, Yin H.

Bletilla striata polysaccharide inhibits angiotensin II-induced ROS and inflammation via NOX4 and TLR2pathways.

Int J Biol Macromol. 2016 Aug;89:376-88. (IF 5.162)

229. Wang J, Tan X, Yang Q, Zeng X, Zhou Y, Luo W, Lin X, Song L, Cai J, Wang T, Wu X.

Inhibition of autophagy promotes apoptosis and enhances anticancer efficacy of adriamycin via augmentedROS generation in prostate cancer cells.

INT J BIOCHEM CELL B. 2016 Aug;77(Pt A):80-90. (IF 3.673)

230. Shuai Y, Liao L, Su X, Yu Y, Shao B, Jing H, Zhang X, Deng Z, Jin Y.

Melatonin Treatment Improves Mesenchymal Stem Cells Therapy by Preserving Stemness during Long-termIn Vitro Expansion.

Theranostics. 2016 Aug 8;6(11):1899-917. (IF 8.579)

231. Chen X, Lv Q, Hong Y, Chen X, Cheng B, Wu T.

IL-1β maintains the redox balance by regulating glutaredoxin 1 expression during oral carcinogenesis.

J Oral Pathol Med. 2016 Sep 22.doi: 10.1111/jop.12502. [Epub ahead of print] (IF 2.495)

232. Yu YX, Li YP, Gao F, Hu QS, Zhang Y, Chen D, Wang GH.

Vitamin K2 suppresses rotenone-induced microglial activation in vitro.

Acta Pharmacol Sin. 2016 Sep;37(9):1178-89. (IF 5.064)

233. Hua P, Sun M, Zhang G, Zhang Y, Song G, Liu Z, Li X, Zhang X, Li B.

Costunolide Induces Apoptosis through Generation of ROS and Activation of P53 in Human EsophagealCancer Eca-109 Cells.

J BIOCHEM MOL TOXIC. 2016 Sep;30(9):462-9. (IF 3.606)

234. Chen W, Wang J, Luo Y, Wang T, Li X, Li A, Li J, Liu K, Liu B.

Ginsenoside Rb1 and compound K improve insulin signaling and inhibit ER stress-associated NLRP3inflammasome activation in adipose tissue.

J Ginseng Res. 2016 Oct;40(4):351-358. (IF 5.487)

235. Jin H, Liu M, Zhang X, Pan J, Han J, Wang Y, Lei H, Ding Y, Yuan Y.

Grape seed procyanidin extract attenuates hypoxic pulmonary hypertension by inhibiting oxidative stressand pulmonary arterial smooth muscle cells proliferation.

J Nutr Biochem. 2016 Oct;36:81-88. (IF 4.873)

236. Zheng QY, Cao ZH, Hu XB, Li GQ, Dong SF, Xu GL, Zhang KQ.

LIGHT/IFN-γ triggers β cells apoptosis via NF-κB/Bcl2-dependent mitochondrial pathway.

J Cell Mol Med. 2016 Oct;20(10):1861-71. (IF 4.486)

237. Wang J, Wu WY, Huang H, Li WZ, Chen HQ, Yin YY.

Biochanin A Protects Against Lipopolysaccharide-Induced Damage of Dopaminergic Neurons Both In Vivoand In Vitro via Inhibition of Microglial Activation.

Neurotox Res. 2016 Oct;30(3):486-98. (IF 2.992)

238. Cui Y, Li H, Wu S, Zhao R, Du D, Ding Y, Nie H, Ji HL.

Formaldehyde impairs transepithelial sodium transport.

SCI REP-UK. 2016 Oct 20;6:35857. (IF 3.998)

239. Wang J, Li J, Liu J, Xu M, Tong X, Wang J.

Chlorogenic acid prevents isoproterenol-induced DNA damage in vascular smooth muscle cells.

Mol Med Rep. 2016 Nov;14(5):4063-4068. (IF 2.1)

240. Yang D, Tan X, Lv Z, Liu B, Baiyun R, Lu J, Zhang Z.

Regulation of Sirt1/Nrf2/TNF-α signaling pathway by luteolin is critical to attenuate acute mercuric chlorideexposure induced hepatotoxicity.

SCI REP-UK. 2016 Nov 17;6:37157. (IF 3.998)

241. Wang D, Meng G, Zheng M, Zhang Y, Chen A, Wu J, Wei J.

The Glutaminase-1 Inhibitor 968 Enhances Dihydroartemisinin-Mediated Antitumor Efficacy in HepatocellularCarcinoma Cells.

PLoS One. 2016 Nov 11;11(11):e0166423. (IF 2.74)

242. Zhang S, Liu C, Li Y, Imam MU, Huang H, Liu H, Xin Y, Zhang H.

Novel Role of ER Stress and Autophagy in Microcystin-LR Induced Apoptosis in Chinese Hamster OvaryCells.

Front Physiol. 2016 Nov 8;7:527. (IF 3.367)

243. Zhang Z, Duan Q, Zhao H, Liu T, Wu H, Shen Q, Wang C, Yin T.

Gemcitabine treatment promotes pancreatic cancer stemness through the Nox/ROS/NF-κB/STAT3 signalingcascade.

Cancer Lett. 2016 Nov 1;382(1):53-63. (IF 7.36)

244. Wang M, Li Y, HuangFu M, Xiao Y, Zhang T, Han M, Xu D, Li F, Ling D, Jin Y, Gao J.

Pluronic-attached polyamidoamine dendrimer conjugates overcome drug resistance in breast cancer.

NANOMEDICINE-UK. 2016 Nov;11(22):2917-2934. (IF 4.3)

245. Yang Y, Zhang K, Wang Y, Li M, Sun X, Liang Z, Wang L, Chen L, Yang H, Zhu L.

Disulfiram chelated with copper promotes apoptosis in human breast cancer cells by impairing themitochondria functions.

Scanning. 2016 Nov;38(6):825-836. (IF 1.33)

246. Liang W, Cai A, Chen G, Xi H, Wu X, Cui J, Zhang K, Zhao X, Yu J, Wei B, Chen L.

Shikonin induces mitochondria-mediated apoptosis and enhances chemotherapeutic sensitivity of gastriccancer through reactive oxygen species.

SCI REP-UK. 2016 Dec 1;6:38267. (IF 3.998)

247. Chen L, Liu DH, Zhang X, Zhang EH, Liu C, Su DF, Cai GJ.

Baroreflex deficiency aggravates atherosclerosis via α7 nicotinic acetylcholine receptor in mice.

VASC PHARMACOL. 2016 Dec;87:92-99. (IF 4.152)

248. Jiang P, Yuan L, Huang G, Wang X, Li X, Jiao L, Zhang L.

Structural properities and immunoenhancement of an exopolysaccharide produced

Int J Biol Macromol. 2016 Dec;93(Pt A):566-571. (IF 5.162)

249. Wang Y, Wu Y, Wang Y, Fu A, Gong L, Li W, Li Y.

Bacillus amyloliquefaciens SC06 alleviates the oxidative stress of IPEC-1 via modulating Nrf2/Keap1signaling pathway and decreasing ROS production.

APPL MICROBIOL BIOT. 2016 Dec 12.[Epub ahead of print] (IF 3.53)

250. Li P, Zheng X, Shou K, Niu Y, Jian C, Zhao Y, Yi W, Hu X, Yu A.

The iron chelator Dp44mT suppresses osteosarcoma's proliferation, invasion and migration: in vitro and invivo.

Am J Transl Res. 2016 Dec 15;8(12):5370-5385. (IF 3.375)

251. Hu Q, Wei J, Liu Y, Fei X, Hao Y, Pei D, Di D.

Discovery and identification of potential biomarkers for alcohol-induced oxidative stress based on cellularmetabolomics.

Biomed Chromatogr. 2016 Dec 7.doi: 10.1002/bmc.3907. [Epub ahead of print] (IF 1.728)

252. Zhang N, Wei WY, Yang Z, Che Y, Jin YG, Liao HH, Wang SS, Deng W, Tang QZ.

Nobiletin,a Polymethoxy Flavonoid, Protects Against Cardiac Hypertrophy Induced by Pressure-Overload via Inhibition of NAPDH Oxidases and Endoplasmic Reticulum Stress.

CELL PHYSIOL BIOCHEM. 2017;42(4):1313-1325. (IF 5.5)

253. Zhang S, Zhang L, Zhang H, Fan G, Qiu J, Fang Z, Wu H, Wang Y, Zhao X.

Hongjingtian Injection Attenuates Myocardial Oxidative Damage via Promoting Autophagy and Inhibiting Apoptosis.

Oxid Med Cell Longev. 2017;2017:6965739. (IF 5.076)

254. Yu Z, Zhu Y, Qin W, Yin J, Qiu J.

Oxidative Stress Induced by Polymyxin E Is Involved in Rapid Killing of Paenibacillus polymyxa.

Biomed Res Int. 2017;2017:5437139. (IF 2.276)

255. Li T, Song X, Zhang J, Zhao L, Shi Y, Li Z, Liu J, Liu N, Yan Y, Xiao Y, Tian X, Sun W, Guan Y, Liu B1

Protection of Human Umbilical Vein Endothelial Cells against Oxidative Stress by MicroRNA-210.

Oxid Med Cell Longev. 2017;2017:3565613. (IF 5.076)

256. Jiang W, Huang W, Chen Y, Zou M, Peng D, Chen D.

HIV-1 Transactivator Protein Induces ZO-1 and Neprilysin Dysfunction in Brain Endothelial Cellsvia the Ras Signaling Pathway.

Oxid Med Cell Longev. 2017;2017:3160360. (IF 5.076)

257. Mu X, Zhang Y, Li J, Xia J, Chen X, Jing P, Song X, Wang L, Wang Y.

Angelica Sinensis Polysaccharide Prevents Hematopoietic Stem Cells Senescence in D-Galactose-Induced Aging Mouse Model.

Stem Cells Int. 2017;2017:3508907. (IF 3.869)

258. Yang W, Huang J, Xiao B, Liu Y, Zhu Y, Wang F, Sun S.

Taurine Protects Mouse Spermatocytes from Ionizing Radiation-Induced Damage Through Activation of Nrf2/HO-1 Signaling.

CELL PHYSIOL BIOCHEM. 2017;44(4):1629-1639. (IF 5.5)

259. Lv C, Maharjan S, Wang Q, Sun Y, Han X, Wang S, Mao Z, Xin Y, Zhang B.

α-Lipoic Acid Promotes Neurological Recovery After Ischemic Stroke by Activating the Nrf2/HO-1Pathway to Attenuate Oxidative Damage.

CELL PHYSIOL BIOCHEM. 2017;43(3):1273-1287. (IF 5.5)

260. Zhang M, Pan H, Xu Y, Wang X, Qiu Z, Jiang L.

Allicin Decreases Lipopolysaccharide-Induced Oxidative Stress and Inflammation in HumanUmbilical Vein Endothelial Cells through Suppression of Mitochondrial Dysfunction and Activation of Nrf2.

CELL PHYSIOL BIOCHEM. 2017;41(6):2255-2267. (IF 5.5)

261. Chen S, Zhao L, Deng X, Shi D, Wu F, Liang H, Huang D, Shao Z.

Mesenchymal Stem Cells Protect Nucleus Pulposus Cells from Compression-Induced Apoptosis by Inhibiting the Mitochondrial Pathway.

Stem Cells Int. 2017;2017:9843120. (IF 3.869)

262. Wang J, Li T, Zang L, Pan X, Wang S, Wu Y, Wang G.

Apigenin Inhibits Human SW620 Cell Growth by Targeting Polyamine Catabolism.

EVID-BASED COMPL ALT. 2017;2017:3684581. (IF 1.813)

263. Ji J, Zhu P, Sun C, Sun J, An L, Zhang Y, Sun X.

Pathway of 3-MCPD-induced apoptosis in human embryonic kidney cells.

J Toxicol Sci. 2017;42(1):43-52. (IF 1.737)

264. Li S, Liu X, Lei J, Yang J, Tian P, Gao Y.

Crocin Protects Podocytes Against Oxidative Stress and Inflammation Induced by High Glucose Through Inhibition of NF-κB.

CELL PHYSIOL BIOCHEM. 2017;42(4):1481-1492. (IF 5.5)

265. .Cao XN, Shen LJ, Wu SD, Yan C, Zhou Y, Xiong G, Wang YC, Liu Y, Liu B, Tang XL, Guo M, Liu DY, Long CL, Sun M, He DW, Lin T, Wei GH.

Urban fine particulate matter exposure causes male reproductive injury through destroyingblood-testis barrier (BTB) integrity.

Toxicol Lett. 2017 Jan 15;266:1-12. (IF 3.569)

266. Ma C, Pi C, Yang Y, Lin L, Shi Y, Li Y, Li Y, He X.

Nampt Expression Decreases Age-Related Senescence in Rat Bone Marrow Mesenchymal StemCells by Targeting Sirt1.

PLoS One. 2017 Jan 26;12(1):e0170930. (IF 2.74)

267. Huang S, Huang S, Wang X, Zhang Q, Liu J, Leng Y.

Downregulation of lipin-1 induces insulin resistance by increasing intracellular ceramideaccumulation in C2C12 myotubes.

Int J Biol Sci. 2017 Jan 1;13(1):1-12. (IF 4.858)

268. Peng Z, Yang X, Qin J, Ye K, Wang X, Shi H, Jiang M, Liu X, Lu X.

Glyoxalase-1 Overexpression Reverses Defective Proangiogenic Function of Diabetic Adipose-Derived Stem Cells in Streptozotocin-Induced Diabetic Mice Model of Critical Limb Ischemia.

STEM CELL TRANSL MED. 2017 Jan;6(1):261-271. (IF 6.429)

269. Gu S, Xv Y, Fei C, Xiao C, Guo J, Zhao Y, Xv F, Li X, Chang C.

Labile plasma iron, more practical and more sensitive to iron overload in myelodysplasticsyndromes.

Hematology. 2017 Jan;22(1):9-15. Epub 2016 Aug 11. (IF 1.65)

270. Shen J, Xu S, Zhou H, Liu H, Jiang W, Hao J, Hu Z.

IL-1β induces apoptosis and autophagy via mitochondria pathway in human degenerativenucleus pulposus cells.

SCI REP-UK. 2017 Jan 25;7:41067. (IF 3.998)

271. Ma C, Shi L, Huang Y, Shen L, Peng H, Zhu X, Zhou G.

Correction: Nanoparticle delivery of Wnt-1 siRNA enhances photodynamic therapy by inhibiting epithelial-mesenchymal transition for oral cancer.

BIOMATER SCI-UK. 2017 Jan 30. doi: 10.1039/c7bm90004j. (IF 6.183)

272. Cao XN, Shen LJ, Wu SD, Yan C, Zhou Y, Xiong G, Wang YC, Liu Y, Liu B, Tang XL, Guo M, Liu DY, Long CL, Sun M, He DW, Lin T, Wei GH.

Urban fine particulate matter exposure causes male reproductive injury through destroying blood-testisbarrier (BTB) integrity.

Toxicol Lett. 2017 Jan 15;266:1-12. (IF 3.569)

273. Xu L, Xu QH, Zhou XY, Yin LY, Guan PP, Zhang T, Liu JX.

Mechanisms of silver_nanoparticles induced hypopigmentation in embryonic zebrafish.

Aquat Toxicol. 2017 Jan 12;184:49-60. (IF 4.344)

274. Mehmood T, Maryam A, Zhang H, Li Y, Khan M, Ma T.

Deoxyelephantopin induces apoptosis in HepG2 cells via oxidative stress, NF-κB inhibition andmitochondrial dysfunction.

Biofactors. 2017 Jan 2;43(1):63-72. (IF 4.734)

275. Lin XL, Liu Y, Liu M, Hu H, Pan Y, Fan XJ, Hu XM, Zou WW.

Inhibition of Hydrogen Peroxide-Induced Human Umbilical Vein Endothelial Cells Aging by Allicin Dependson Sirtuin1 Activation.

MED SCI MONITOR. 2017 Jan 31;23:563-570. (IF 1.918)

276. He W, Cui L, Zhang C, Zhang X, He J, Xie Y, Chen Y.

Sonic hedgehog promotes neurite outgrowth of cortical neurons under oxidative stress: Involving ofmitochondria and energy metabolism.

Exp Cell Res. 2017 Jan 1;350(1):83-90. (IF 3.383)

277. Huang S, Huang S, Wang X, Zhang Q, Liu J, Leng Y.

Downregulation of lipin-1 induces insulin resistance by increasing intracellular ceramide accumulation inC2C12 myotubes.

Int J Biol Sci. 2017 Jan 1;13(1):1-12. (IF 4.858)

278. Ma C, Pi C, Yang Y, Lin L, Shi Y, Li Y, Li Y, He X.

Nampt Expression Decreases Age-Related Senescence in Rat Bone Marrow Mesenchymal Stem Cells byTargeting Sirt1.

PLoS One. 2017 Jan 26;12(1):e0170930. (IF 2.74)

279. Di W, Khan M, Gao Y, Cui J, Wang D, Qu M, Feng L, Maryam A, Gao H.

Vitamin K4 inhibits the proliferation and induces apoptosis of U2OS osteosarcoma cells via mitochondrialdysfunction.

Mol Med Rep. 2017 Jan;15(1):277-284. (IF 2.1)

280. Mehmood T, Maryam A, Zhang H, Li Y, Khan M, Ma T.

Deoxyelephantopin induces apoptosis in HepG2 cells via oxidative stress,NF-κB inhibition and mitochondrial dysfunction.

Biofactors. 2017 Jan 2;43(1):63-72. (IF 4.734)

281. Wang SQ, Wang C, Wang JW, Yang DX, Wang R, Wang CJ, Li HJ, Shi HG, Ke Y, Liu HM.

Geridonin,a novel derivative of oridonin, inhibits proliferation of MGC 803 cells bothin vitro and in vivo through elevating the intracellular ROS.

J Pharm Pharmacol. 2017 Feb;69(2):213-221. (IF 2.571)

282. Zhou Q, Song W, Xiao W.

Dioscin induces demethylation of DAPK-1 and RASSF-1alpha genes via the antioxidant capacity, resulting in apoptosis of bladder cancer T24 cells.

EXCLI J. 2017 Feb 17;16:101-112. (IF 2.837)

283. Jian KL, Zhang C, Shang ZC, Yang L, Kong LY.

Eucalrobusone C suppresses cell proliferation and induces ROS-dependent mitochondrialapoptosis via the p38 MAPK pathway in hepatocellular carcinoma cells.

Phytomedicine. 2017 Feb 15;25:71-82. (IF 4.268)

284. Zhao T, Jin W, Pan H, Li H, Zhao Y, Feng Y.

Rosbin,a synthetic small molecule, induces A549 cells apoptosis through a ROS-mediatedpathway.

Cell Biol Int. 2017 Feb;41(2):221-226. (IF 2.571)

285. Zhang JX, Wang R, Xi J, Shen L, Zhu AY, Qi Q, Wang QY, Zhang LJ, Wang FC, Lü HZ, Hu JG.

Morroniside protects SK-N-SH human neuroblastoma cells against H2O2-induced damage.

Int J Mol Med. 2017 Feb 8. (IF 3.098)

286. Wang SQ, Wang C, Wang JW, Yang DX, Wang R, Wang CJ, Li HJ, Shi HG, Ke Y, Liu HM.

Geridonin, a novel derivative of oridonin, inhibits proliferation of MGC 803 cells both in vitro and in vivothrough elevating the intracellular ROS.

J Pharm Pharmacol. 2017 Feb;69(2):213-221. (IF 2.571)

287. Song P, Wang Z, Zhang X, Fan J, Li Y, Chen Q, Wang S, Liu P, Luan J, Ye L, Ju D.

The role of autophagy in asparaginase-induced immune suppression of macrophages.

Cell Death Dis. 2017 Mar 30;8(3):e2721. (IF 6.304)

288. Wang L, Chen H, Xu J, Xu Q, Wang M, Zhao D, Wang L, Song L.

Crustacean hyperglycemic hormones directly modulate the immune response of hemocytes in shrimp Litopenaeus vannamei.

FISH SHELLFISH IMMUN. 2017 Mar;62:164-174. (IF 3.298)

289. Zhang A, Sheng Y, Zou M.

Antiproliferative activity of Alisol B in MDA-MB-231 cells is mediated by apoptosis, dysregulation of mitochondrial functions, cell cycle arrest and generation of reactive oxygen species.

Biomed Pharmacother. 2017 Mar;87:110-117. (IF 4.545)

290. Wu H, Jiang K, Yin N, Ma X, Zhao G, Qiu C, Deng G.

Thymol mitigates lipopolysaccharide-induced endometritis by regulating the TLR4- and ROS-mediated NF-κB signaling pathways.

ONCOTARGET. 2017 Mar 21;8(12):20042-20055. (IF 5.168)

291. Qiu M, Chen L, Tan G, Ke L, Zhang S, Chen H, Liu J.

JS-K promotes apoptosis by inducing ROS production in human prostate cancer cells.

Oncol Lett. 2017 Mar;13(3):1137-1142. (IF 2.311)

292. Yang X, Huo F, Liu B, Liu J, Chen T, Li J, Zhu Z, Lv B.

Crocin Inhibits Oxidative Stress and Pro-inflammatory Response of Microglial Cells Associated with Diabetic Retinopathy Throughthe Activation of PI3K/Akt Signaling Pathway.

J Mol Neurosci. 2017 Apr;61(4):581-589. (IF 2.678)

293. Jia Y, Wang HD, Wang Q, Ding H, Wu HM, Pan H.

GSH depletion and consequent AKT inhibition contribute tothe Nrf2 knockdown-induceddecrease in proliferation in glioblastoma U251 cells.

Oncol Rep. 2017 Apr;37(4):2252-2260. (IF 3.417)

294. Zhang XM, Zhao YQ, Yan H, Liu H, Huang GW.

Inhibitory effect of homocysteine on rat neural stem cell growth in vitro is associated with reduced protein levels and enzymatic activities of aconitase and respiratory complex III.

J Bioenerg Biomembr. 2017 Apr;49(2):131-138. (IF 2.524)

295. Wang Y, Wu Y, Wang Y, Fu A, Gong L, Li W, Li Y.

Bacillus amyloliquefaciens SC06 alleviates the oxidative stress of IPEC-1 via modulatingNrf2/Keap1 signaling pathway and decreasing ROS production.

APPL MICROBIOL BIOT. 2017 Apr;101(7):3015-3026. (IF 3.53)

296. Liao G, Ye Z, Liu Y, Fu B, Fu C.

Octahedral ruthenium (II) polypyridyl complexes as antimicrobial agents against mycobacterium.

PeerJ. 2017 Apr 27;5:e3252. (IF 2.379)

297. Xie J, Yong Y, Dong X, Du J, Guo Z, Gong L, Zhu S, Tian G, Yu S, Gu Z, Zhao Y.

Therapeutic Nanoparticles Based on Curcumin and Bamboo Charcoal Nanoparticles for Chemo-Photothermal Synergistic Treatment of Cancer and Radioprotection of Normal Cells.

ACS APPL MATER INTER. 2017 Apr 26;9(16):14281-14291. (IF 8.758)

298. Meng J, Lv Z, Qiao X, Li X, Li Y, Zhang Y, Chen C.

The decay of Redox-stress Response Capacity is a substantive characteristic of aging: Revising the redox theory of aging.

Redox Biol. 2017 Apr;11:365-374. (IF 9.986)

299. Zhu Z, Fan X, Pan Y, Lu Y, Zeng W.

Trehalose improves rabbit sperm quality during cryopreservation.

Cryobiology. 2017 Apr;75:45-51. (IF 2.283)

300. Wang G, Zhang T, Sun W, Wang H, Yin F, Wang Z, Zuo D, Sun M, Zhou Z, Lin B, Xu J, Hua Y, Li H, Cai Z.

Arsenic sulfide induces apoptosis and autophagy throughthe activation of ROS/JNK and suppression of Akt/mTOR signaling pathways in osteosarcoma.

FREE RADICAL BIO MED. 2017 May;106:24-37. (IF 6.17)

301. Li Z, Tan J, Shao L, Dong X, Ye RD, Chen D.

Selenium-mediated protection in reversing the sensitivity of bacterium to the bactericidalantibiotics.

J TRACE ELEM MED BIO . 2017 May;41:23-31. (IF 3.755)

302. Chen X, Lv Q, Hong Y, Chen X, Cheng B, Wu T.

IL-1β maintains the redox balance by regulating glutaredoxin 1 expression during oralcarcinogenesis.

J Oral Pathol Med. 2017 May;46(5):332-339. (IF 2.495)

303. Li Y, Chang J, Cui Y, Zhao R, Ding Y, Hou Y, Zhou Z, Ji HL, Nie H.

Novel mechanisms for crotonaldehyde-induced lung edema.

ONCOTARGET. 2017 May 12;8(48):83509-83522. (IF 5.168)

304. Que Z, Wang P, Hu Y, Xue Y, Liu X, Qu C, Ma J, Liu Y.

Dihydroartemisin inhibits glioma invasiveness via a ROS to P53 to β-catenin signaling.

Pharmacol Res. 2017 May;119:72-88. (IF 5.893)

305. Wu QF, Qian C, Zhao N, Dong Q, Li J, Wang BB, Chen L, Yu L, Han B, Du YM, Liao YH.

Activation of transient receptor potential vanilloid 4 involves in hypoxia/reoxygenation injury in cardiomyocytes.

Cell Death Dis. 2017 May 25;8(5):e2828. (IF 6.304)

306. Wang C, Liu J, Tian Z, Tian M, Tian L, Zhao W, Liu Z.

Half-sandwich iridium N-heterocyclic carbene anticancer complexes.

DALTON T. 2017 May 30;46(21):6870-6883. (IF 4.174)

307. Huang Y, He Q.

Inhibition of c-Src protects paraquat induced microvascular endothelial injury by modulatingcaveolin-1 phosphorylation and caveolae mediated transcellular permeability.

ENVIRON TOXICOL CHEM. 2017 Jun;52:62-68. (IF 3.152)

308. Tian X, He W, Yang R, Liu Y.

Dl-3-n-butylphthalide protects the heart against ischemic injury and H9c2 cardiomyoblastsagainst oxidative stress: involvement of mitochondrial function and biogenesis.

J Biomed Sci. 2017 Jun 15;24(1):38. (IF 5.762)

309. Liu Y, Jiang Y, Wang N, Jin Q, Ji F, Zhong C, Zhang Z, Yang J, Ye X, Chen T.

Invalidation of mitophagy by FBP1-mediated repression promotes apoptosis in breast cancer.

TUMOR BIOL . 2017 Jun;39(6):1010428317708779. (IF 3.65)

310. Gao HE, Sun Y, Ding YH, Long J, Liu XL, Yang M, Ji Q, Li YH, Chen Y, Zhang Q, Gao YD.

Antineoplastic effects of CPPTL via the ROS/JNK pathway in acute myeloid leukemia.

ONCOTARGET. 2017 Jun 13;8(24):38990-39000. (IF 5.168)

311. Rao Z, Wang S, Wang J.

Peroxiredoxin 4 inhibits IL-1β-induced chondrocyte apoptosis via PI3K/AKT signaling.

Biomed Pharmacother. 2017 Jun;90:414-420. (IF 4.545)

312. Ren Y, Li Y, Yan J, Ma M, Zhou D, Xue Z, Zhang Z, Liu H, Yang H, Jia L, Zhang L, Zhang Q, Mu S, Zhang R, Da Y.

Adiponectin modulates oxidative stress-induced mitophagy and protects C2C12 myoblastsagainst apoptosis.

SCI REP-UK. 2017 Jun 9;7(1):3209. (IF 3.998)

313. Zhang J, Yang S, Li H, Chen F, Shi J.

Naringin ameliorates diabetic nephropathy by inhibiting NADPH oxidase 4.

Eur J Pharmacol. 2017 Jun 5;804:1-6. (IF 3.263)

314. Wei JL, Fang M, Fu ZX, Zhang SR, Guo JB, Wang R, Lv ZB, Xiong YF.

Sestrin 2 suppresses cells proliferation through AMPK/mTORC1 pathway activation in colorectalcancer.

ONCOTARGET. 2017 Jul 25;8(30):49318-49328. (IF 5.168)

315. Fan W, Han D, Sun Z, Ma S, Gao L, Chen J, Li X, Li X, Fan M, Li C, Hu D, Wang Y, Cao F.

Endothelial deletion of mTORC1 protects against hindlimb ischemia in diabetic mice viaactivation of autophagy, attenuation of oxidative stress and alleviation of inflammation.

FREE RADICAL BIO MED. 2017 Jul;108:725-740. (IF 6.17)

316. Zhao H, Liu Q, Wang S, Dai F, Cheng X, Cheng X, Chen W, Zhang M, Chen D.

In vitro additive antitumor effects of dimethoxycurcumin and 5-fluorouracil in colon cancer cells.

CANCER MED-US. 2017 Jul;6(7):1698-1706. (IF 3.491)

317. Zhang Y, Lv T, Zhang H, Xie X, Li Z, Chen H, Gao Y.

Folate and Heptamethine Cyanine Modified Chitosan-Based Nanotheranostics for Tumor TargetedNear-Infrared Fluorescence Imaging and Photodynamic Therapy.

Biomacromolecules. 2017 Jul 10;18(7):2146-2160. (IF 6.092)

318. Zhao K, Li G, Yao Y, Zhou Y, Li Z, Guo Q, Lu N.

Activation of phospholipase C-γ1and translocation of phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase contribute to GL-V9-induced apoptosis in human gastric cancer cells.

Exp Cell Res. 2017 Jul 1;356(1):8-19. (IF 3.383)

319. Li D, Zhao Y, Ding W, Zhao P, Xu JW, Li T, Ma H, Yu X.

A strategy for promoting lipid production in green microalgae Monoraphidium sp. QLY-1 by combined melatonin and photoinduction.

BIORESOURCE TECHNOL. 2017 Jul;235:104-112. (IF 7.539)

320. Zhang L, Li J, Hu J, Li D, Wang X, Zhang R, Zhang H, Shi M, Chen H.

Cigarette smoke extract induces EGFR-TKI resistance via promoting EGFR signaling pathway and ROS generation in NSCLC cell lines.

Lung Cancer. 2017 Jul;109:109-116. (IF 4.702)

321. Zhou B, Wang X, Li F, Wang Y, Yang L, Zhen X, Tan W.

Mitochondrial activity and oxidative stress functions are influenced bythe activation of AhR-induced CYP1A1 overexpression in cardiomyocytes.

Mol Med Rep. 2017 Jul;16(1):174-180. (IF 2.1)

322. Zhu Z, Ren Z, Fan X, Pan Y, Lv S, Pan C, Lei A, Zeng W.

Cysteine protects rabbit spermatozoa against reactive oxygen species-induced damages.

PLoS One. 2017 Jul 10;12(7):e0181110. (IF 2.74)

323. Qiu M, Ke L, Zhang S, Zeng X, Fang Z, Liu J.

JS-K,a GST-activated nitric oxide donor prodrug, enhances chemo-sensitivity in renal carcinomacells and prevents cardiac myocytes toxicity induced by Doxorubicin.

CANCER CHEMOTH PHARM. 2017 Aug;80(2):275-286. (IF 2.967)

324. Li W, Li Y, Sun R, Zhou S, Li M, Feng M, Xie Y.

Dual character of flavonoids in attenuating and aggravating ischemia-reperfusion-inducedmyocardial injury.

Exp Ther Med. 2017 Aug;14(2):1307-1314. (IF 1.785)

325. Zhao X, Wang R, Xiong J, Yan D, Li A, Wang S, Xu J, Zhou J.

JWA antagonizes paraquat-induced neurotoxicity via activation of Nrf2.

Toxicol Lett. 2017 Aug 5;277:32-40. (IF 3.569)

326. Meng W, Pei Z, Feng Y, Zhao J, Chen Y, Shi W, Xu Q, Lin F, Sun M, Xiao K.

Neglected role of hydrogen sulfide in sulfur mustard poisoning: Keap1 S-sulfhydration and subs equent Nrf2 pathway activation.

SCI REP-UK. 2017 Aug 25;7(1):9433. (IF 3.998)

327. Zeng Z, Li M, Wang M, Wu X, Li Q, Ning Q, Zhao J, Xu Y, Xie J.

Increased expression of Siglec-9 in chronic obstructive pulmonary disease.

SCI REP-UK. 2017 Aug 31;7(1):10116. (IF 3.998)

328. Zhang Z, Li S, Jiang H, Liu B, Lv Z, Guo C, Zhang H.

Effects of selenium on apoptosis and abnormal amino acid metabolism induced by excess fattyacid in isolated rat hepatocytes.

Mol Nutr Food Res. 2017 Sep;61(9). (IF 5.309)

329. Su J, Zhou X, Yin X, Wang L, Zhao Z, Hou Y, Zheng N, Xia J, Wang Z.

The effects of curcumin on proliferation, apoptosis, invasion,and NEDD4 expression in pancreatic cancer.

Biochem Pharmacol. 2017 Sep 15;140:28-40. (IF 4.96)

330. Bai H, Wu M, Zhang H, Tang G.

Chronic polycyclic aromatic hydrocarbon exposure causes DNA damage and genomic instability in lung epithelial cells.

ONCOTARGET. 2017 Sep 15;8(45):79034-79045. (IF 5.168)

331. Cui J, Wang J, Zheng M, Gou D, Liu C, Zhou Y.

Ginsenoside Rg2 protects PC12 cells against β-amyloid25-35-induced apoptosis via the phosphoinositide 3-kinase/Akt pathway.

CHEM-BIOL INTERACT. 2017 Sep 25;275:152-161. (IF 3.723)

332. Yan B, Peng Z, Xing X, Du C.

Glibenclamide induces apoptosis by activating reactive oxygen species dependent JNK pathway in hepatocellular carcinoma cells.

BIOSCIENCE REP. 2017 Sep 27;37(5). pii: BSR20170685. (IF 2.942)

333. Wang J, Qi L, Mei L, Wu Z.

Curcumin inhibits the proliferation and induces apoptosis in HT-29 cell lines througha reactiveoxygen species (ROS)-dependent mechanism.

Pak J Pharm Sci. 2017 Sep;30(5):1671-1677. (IF 0.562)

334. He X, Wu C, Cui Y, Zhu H, Gao Z, Li B, Hua J, Zhao B.

The aldehyde group of gossypol induces mitochondrial apoptosis via ROS-SIRT1-p53-PUMApathway in male germline stem cell.

ONCOTARGET. 2017 Oct 24;8(59):100128-100140. (IF 5.168)

335. Zhong Y, Jin C, Gan J, Wang X, Shi Z, Xia X, Peng X.

Apigenin attenuates patulin-induced apoptosis in HEK293 cells by modulating ROS-mediatedmitochondrial dysfunction and caspase signal pathway.

Toxicon. 2017 Oct;137:106-113. (IF 2.201)

336. Zhu Z, Fan X, Lv Y, Lin Y, Wu, Zeng W.

Glutamine protects rabbit spermatozoa against oxidative stress via glutathione synthesis during cryopreservation.

REPROD FERT DEVELOP. 2017 Oct;29(11):2183-2194. (IF 1.718)

337. Hao XD, Chen P, Zhang YY, Li SX, Shi WY, Gao H.

De novo mutations of TUBA3D are associated with keratoconus.

SCI REP-UK. 2017 Oct 19;7(1):13570. (IF 3.998)

338. Wang DD, Liu Y, Li N, Zhang Y, Jin Q, Hao DC, Piao HL, Dai ZR, Ge GB, Yang L.

Induction of CYP1A1 increases gefitinib-induced oxidative stress and apoptosis in A549 cells.

Toxicol In Vitro. 2017 Oct;44:36-43. (IF 2.959)

339. You M, Li K, Xie Y, Huang L, Zheng X.

The Effects of Cerium Valence States at Cerium Oxide Coatings onthe Responses of BoneMesenchymal Stem Cells and Macrophages.

Biol Trace Elem Res. 2017 Oct;179(2):259-270. (IF 2.639)

340. You M, Li K, Xie Y, Huang L, Zheng X.

The Effects of Cerium Valence States at Cerium Oxide Coatings onthe Responses of BoneMesenchymal Stem Cells and Macrophages.

Biol Trace Elem Res. 2017 Oct;179(2):259-270. (IF 2.639)

341. Feng RB, Wang Y, He C, Yang Y, Wan JB.

Gallic acid,a natural polyphenol, protects against tert-butyl hydroperoxide-induced hepatotoxicity by activating ERK-Nrf2-Keap1-mediated antioxidative response.

Food Chem Toxicol. 2017 Oct 21. pii: S0278-6915(17)30631-2. (IF 4.679)

342. Jia Z, Wang L, Jiang S, Sun M, Wang M, Yi Q, Song L.

Functional characterization of hemocytes from Chinese mitten crab Eriocheir sinensis by flowcytometry.

FISH SHELLFISH IMMUN. 2017 Oct;69:15-25. (IF 3.298)

343. Mehmood T, Maryam A, Tian X, Khan M, Ma T.

Santamarine Inhibits NF-кBand STAT3 Activation and Induces Apoptosis in HepG2 Liver CancerCells via Oxidative Stress.

J Cancer. 2017 Oct 17;8(18):3707-3717. (IF 3.565)

344. Xia W, Zhuang L, Deng X, Hou M.

Long noncoding RNA p21 modulates cellular senescence via the Wnt/β catenin signaling pathway in mesenchymal stem cells.

Mol Med Rep. 2017 Nov;16(5):7039-7047. (IF 2.1)

345. Li X, Wang B, Tang L, Zhang Y, Chen L, Gu L, Zhang F, Ouyang J, Zhang X.

GSTA1 expression is correlated with aldosterone level in KCNJ5-mutated adrenal aldosterone-producing adenoma.

J CLIN ENDOCR METAB. 2017 Nov 20. (IF 5.399)

346. Zhang J, Wang Z, Wu A, Nie J, Pei H, Hu W, Wang B, Shang P, Li B, Zhou G.

Differences in responses to X-ray exposure between osteoclast and osteoblast cells.

J Radiat Res. 2017 Nov 1;58(6):791-802. (IF 1.95)

347. Yin J, Ma L, Wang H, Yan H, Hu J, Jiang W, Li Y.

Chinese herbal medicine compound Yi-Zhi-Hao pellet inhibits replication of influenza virusinfection through activation of heme oxygenase-1.

Acta Pharm Sin B. 2017 Nov;7(6):630-637. (IF 7.097)

348. Li W, Yu KN, Ma J, Shen J, Cheng C, Zhou F, Cai Z, Han W.

Non-thermal plasma induces mitochondria-mediated apoptotic signaling pathway via ROSgeneration in HeLa cells.

Arch Biochem Biophys. 2017 Nov 1;633:68-77 (IF 3.391)

349. Wang LJ, Guo CL, Li XQ, Wang SY, Jiang B, Zhao Y, Luo J, Xu K, Liu H, Guo SJ, Wu N, Shi DY.

Discovery of Novel Bromophenol Hybrids as Potential Anticancer Agents throughthe Ros-Mediated Apoptotic Pathway: Design, Synthesis and Biological Evaluation.

Mar Drugs. 2017 Nov 1;15(11). pii: E343. (IF 4.073)

350. Li Y, Luo Y, Luo T, Lu B, Wang C, Zhang Y, Piao M, Feng C, Ge P.

Trehalose Inhibits Protein Aggregation Caused by Transient Ischemic Insults Through Preservation of Proteasome Activity,Not via Induction of Autophagy.

Mol Neurobiol. 2017 Nov;54(9):6857-6869. (IF 4.5)

351. Zhang B, Xu L, Zhuo N, Shen J.

Resveratrol protects against mitochondrial dysfunction through autophagy activation in humannucleus pulposus cells.

BIOCHEM BIOPH RES CO. 2017 Nov 4;493(1):373-381. (IF 2.985)

352. Hu Q, Zhang T, Yi L, Zhou X, Mi M.

Dihydromyricetin inhibits NLRP3 inflammasome-dependent pyroptosis by activating the Nrf2signaling pathway in vascular endothelial cells.

Biofactors. 2017 Nov 29. (IF 4.734)

353. Chen S, Hu M, Shen M, Xu Y, Wang C, Wang X, Li F, Zeng D, Chen F, Zhao G, Chen M, Wang F, Cheng T, Su Y, Zhao J, Wang S, Wang J.

Dopamine induces platelet production from megakaryocytes via oxidative stress-mediatedsignaling pathways.

Platelets. 2017 Nov 9:1-7. (IF 3.378)

354. Yuan G, Hua B, Cai T, Xu L, Li E, Huang Y, Sun N, Yan Z, Lu C, Qian R.

Clock mediates liver senescence by controlling ER stress.

AGING-US. 2017 Dec 22;9(12):2647-2665. (IF 4.831)

355. Wang X, Li Y, Lin M, Jin J, Huang Z.

Rhodium (II) complex with 2-benzoylpyridine, a novel potential chemotherapeutic drug, inducescell cycle arrest and apoptosis in HepG2 cells.

Biometals. 2017 Dec;30(6):903-915. (IF 2.479)

356. Shen Y, Yan Y, Lu L, Qian Y, Guan X, Zhang L, Qi Y, Gu L, Ding F.

Klotho ameliorates hydrogen peroxide-induced oxidative injury in TCMK-1 cells.

Int Urol Nephrol. 2017 Dec 28. (IF 1.843)

357. Yang M, Fang J, Liu Q, Wang Y, Zhang Z.

Role of ROS-TRPM7-ERK1/2 axis in high concentration glucose-mediated proliferation and phenotype switching of rat aortic vascular smooth muscle cells.

BIOCHEM BIOPH RES CO. 2017 Dec 16;494(3-4):526-533. (IF 2.985)

358. Zhao R, Guo Z, Zhang R, Deng C, Xu J, Dong W, Hong Z, Yu H, Situ H, Liu C, Zhuang G.

Nasal epithelial barrier disruption by particulate matter ≤2.5 μm via tight junction proteindegradation.

J Appl Toxicol. 2017 Dec 13. (IF 2.997)

359. Xiao Y, Meng C, Lin J, Huang C, Zhang X, Long Y, Huang Y, Lin Y.

Ouabain targets the Na+/K+-ATPase α3 isoform to inhibit cancer cell proliferation and induceapoptosis.

Oncol Lett. 2017 Dec;14(6):6678-6684. (IF 2.311)

360. Du X, Shi Z, Peng Z, Zhao C, Zhang Y, Wang Z, Li X, Liu G, Li X.

Acetoacetate induces hepatocytes apoptosis by the ROS-mediated MAPKs pathway in ketoticcows.

J Cell Physiol. 2017 Dec;232(12):3296-3308. (IF 5.546)

361. Fu J, Yang Q, Li Y, Li P, Wang L, Li X.

A mechanism bywhich Astragalus polysaccharide protects against ROS toxicity through inhibiting the protein dephosphorylation of boar sperm preserved at 4 °C.

J Cell Physiol. 2017 Dec 12. (IF 5.546)

362. Liu W, Meng Q, Sun Y, Wang C, Huo X, Liu Z, Sun P, Sun H, Ma X, Liu K

Targeting P-Glycoprotein: Nelfinavir Reverses Adriamycin Resistance in K562/ADR Cells.

CELL PHYSIOL BIOCHEM. 2018;51(4):1616-1631. (IF 5.5)

363. Liu Y, Yang B, Zhang L, Cong X, Liu Z, Hu Y, Zhang J, Hu H.

Ginkgolic acid induces interplay between apoptosis and autophagy regulated by ROS generation in colon cancer.

BIOCHEM BIOPH RES CO. 2018 Jan 15. pii: S0006-291X(18)30106-2. (IF 2.985)

364. Lu MC, Jiao Q, Liu T, Tan SJ, Zhou HS, You QD, Jiang ZY.

Discovery ofa head-to-tail cyclic peptide asthe Keap1-Nrf2 protein-protein interaction inhibitor with high cell potency.

Eur J Med Chem. 2018 Jan 1;143:1578-1589. (IF 5.572)

365. Xu T, Yin J, Chen S, Zhang D, Wang H.

Elevated 8-oxo-7,8-dihydro-2'-deoxyguanosine in genome of T24 bladder cancer cells induced by halobenzoquinones.

J ENVIRON SCI-CHINA. 2018 Jan;63:133-139. (IF 3.556)

366. Wang F, Guo T, Jiang H, Li R, Wang T, Zeng N, Dong G, Zeng X, Li D, Xiao Y, Hu Q, Chen W, Xing X, Wang Q.

A comparison of CRISPR/Cas9 and siRNA-mediated ALDH2 gene silencing in human cell lines.

Mol Genet Genomics. 2018 Jan 30. (IF 2.797)

367. Chen Y, Chen S, Liang H, Yang H, Liu L, Zhou K, Xu L, Liu J, Yun L, Lai B, Song L, Luo H, Peng J, Liu Z, Xiao Y, Chen W, Tang H.

Bcl-2 protects TK6 cells against hydroquinone-induced apoptosis through PARP-1 cytoplasmtranslocation and stabilizing mitochondrial membrane potential.

Environ Mol Mutagen. 2018 Jan;59(1):49-59. (IF 3.131)

368. Wang X, Qin J, Zhang X, Peng Z, Ye K, Wu X, Yang X, Shi H, Zhao Z, Guo X, Liu X, Yin M, Lu X.

Functional blocking of Ninjurin1 asa strategy for protecting endothelial cells in diabetes mellitus.

CLIN SCI. 2018 Jan 19;132(2):213-229. (IF 5.223)

369. Qiao C, Ye W, Li S, Wang H, Ding X.

Icariin modulates mitochondrial function and apoptosis in high glucose-induced glomerularpodocytes through G protein-coupled estrogen receptors.

Mol Cell Endocrinol. 2018 Jan 31. pii: S0303-7207(18)30031-5. (IF 3.871)

370. Zhang M, Hou Y, Shen Y, Guo X, Shang D, Zhang D.

Probucol reverses homocysteine induced inflammatory monocytes differentiation and oxidativestress.

Eur J Pharmacol. 2018 Jan 5;818:67-73. (IF 3.263)

371. Jiang LB, Cao L, Ma YQ, Chen Q, Liang Y, Yuan FL, Li XL, Dong J, Chen N.

TIGAR mediates the inhibitory role of hypoxia on ROS production and apoptosis in rat nucleuspulposus cells.

OSTEOARTHR CARTILAGE. 2018 Jan;26(1):138-148. (IF 4.793)

372. Wang HF, Wang ZQ, Ding Y, Piao MH, Feng CS, Chi GF, Luo YN, Ge PF.

Endoplasmic reticulum stress regulates oxygen-glucose deprivation-induced parthanatos in human SH-SY5Y cells via improvement of intracellular ROS.

CNS Neurosci Ther. 2018 Jan;24(1):29-38. (IF 4.074)

373. Hu J, Xue P, Mao X, Xie L, Li G, You Z.

SUMO1/UBC9 decreased Nox1 activity inhibits reactiveoxygenspecies generation and apoptosis in diabetic retinopathy.

Mol Med Rep. 2018 Jan;17(1):1690-1698. (IF 2.1)

374. Liu MX, Jin L, Sun SJ, Liu P, Feng X, Cheng ZL, Liu WR, Guan KL, Shi YH, Yuan HX, Xiong Y.

Metabolic reprogramming by PCK1 promotes TCA cataplerosis, oxidative stress and apoptosis in liver cancer cells and suppresses hepatocellular carcinoma.

Oncogene. 2018 Jan 16. (IF 7.971)

375. Gao X, Zhang X, Hu J, Xu X, Zuo Y, Wang Y, Ding J, Xu H, Zhu S

Aconitine induces apoptosis in H9c2 cardiac cells via mitochondria‑mediated pathway.

Mol Med Rep. 2018 Jan;17(1):284-292. (IF 2.1)

376. Wei X, Yang Y, Jiang YJ, Lei JM, Guo JW, Xiao H

Relaxin ameliorates high glucose-induced cardiomyocyte hypertrophy and apoptosis via the Notch1 pathway.

Exp Ther Med. 2018 Jan;15(1):691-698. (IF 1.785)

377. Li Y, Qin R, Yan H, Wang F, Huang S, Zhang Y, Zhong M, Zhang W, Wang Z

Inhibition of vascular smooth muscle cells premature senescence with rutin attenuates and stabilizes diabetic atherosclerosis.

J Nutr Biochem. 2018 Jan 51:91-98. (IF 4.873)

378. Dai J, Gu L, Su Y, Wang Q, Zhao Y, Chen X, Deng H, Li W, Wang G, Li K

Inhibition of curcumin on influenza A virus infection and influenzal pneumonia via oxidative stress, TLR2/4, p38/JNK MAPK and NF-κB pathways.

Int Immunopharmacol. 2018 Jan 54:177-187. (IF 3.943)

379. Wang Y, Su H, Song X, Fiati Kenston SS, Zhao J, Gu Y

Luteolin inhibits multi-heavy metal mixture-induced HL7702 cell apoptosis through downregulation of ROS-activated mitochondrial pathway.

Int J Mol Med. 2018 Jan 41(1):233-241. (IF 3.098)

380. Zheng WL, Wang BJ, Wang L, Shan YP, Zou H, Song RL, Wang T, Gu JH, Yuan Y, Liu XZ, Zhu GQ, Bai JF, Liu ZP, Bian JC

ROS-Mediated Cell Cycle Arrest and Apoptosis Induced by Zearalenone in Mouse Sertoli Cells via ER Stress and the ATP/AMPK Pathway.

TOXINS. 2018 Jan 1 10(1). pii: E24. (IF 3.531)

381. Zhang Z, Xu S, Wang Y, Yu Y, Li F, Zhu H, Shen Y, Huang S, Guo S

Near-infrared triggered co-delivery of doxorubicin and quercetin by using gold nanocages with tetradecanol to maximize anti-tumor effects on MCF-7/ADR cells.

J COLLOID INTERF SCI. 2018 Jan 1 509:47-57. (IF 7.489)

382. Lin HY, Han HW, Sun WX, Yang YS, Tang CY, Lu GH, Qi JL, Wang XM, Yang YH

Design and characterization of α-lipoic acyl shikonin ester twin drugs as tubulin and PDK1 dual inhibitors.

Eur J Med Chem. 2018 Jan 20 144:137-150. (IF 5.572)

383. Jia D, Li T, Chen X, Ding X, Chai Y, Chen AF, Zhu Z, Zhang C

Salvianic acid A sodium protects HUVEC cells against tert-butyl hydroperoxide induced oxidative injury via mitochondria-dependent pathway.

CHEM-BIOL INTERACT. 2018 Jan 5 279:234-242. (IF 3.723)

384. Wen L, Jiang X, Sun J, Li X, Li X, Tian L, Li Y, Bai W.

Cyanidin-3-O-glucoside promotes the biosynthesis of progesterone throughthe protection of mitochondrial function in Pb-exposed rat leydig cells.

Food Chem Toxicol. 2018 Feb;112:427-434. (IF 4.679)

385. Wang W, Wang R, Zhang Q, Mor G, Zhang H.

Benzo(a)pyren-7,8-dihydrodiol-9,10-epoxide induces human trophoblast Swan 71 celldysfunctions due to cell apoptosis through disorder of mitochondrial fission/fusion.

Environ Pollut. 2018 Feb;233:820-832. (IF 6.792)

386. Pan X, Xu S, Wu J, Luo J, Duan Y, Wang J, Zhang F, Zhou M.

Screening and characterization of Xanthomonas oryzae pv. oryzae strains with resistance to pheazine-1-carboxylic acid.

PESTIC BIOCHEM PHYS. 2018 Feb;145:8-14. (IF 2.751)

387. Wu X, Zhang H, Qi W, Zhang Y, Li J, Li Z, Lin Y, Bai X, Liu X, Chen X, Yang H, Xu C, Zhang Y, Yang B.

Nicotine promotes atherosclerosis via ROS-NLRP3-mediated endothelial cell pyroptosis.

Cell Death Dis. 2018 Feb 7;9(2):171. (IF 6.304)

388. Yu N, Wang S, Song X, Gao L, Li W, Yu H, Zhou C, Wang Z, Li F, Jiang Q.

Low-Dose Radiation Promotes Dendritic Cell Migration and IL-12 Production via the ATM/NF-kappaB Pathway.

Radiat Res. 2018 Feb 8. (IF 2.657)

389. Li L, Ren F, Qi C, Xu L, Fang Y, Liang M, Feng J, Chen B, Ning W, Cao J.

Intermittent hypoxia promotes melanoma lung metastasis via oxidative stress and inflammationresponses in a mouse model of obstructive sleep apnea.

RESP RES . 2018 Feb 12;19(1):28. (IF 3.751)

390. Wang Z, Zhou F, Dou Y, Tian X, Liu C, Li H, Shen H, Chen G.

Melatonin Alleviates Intracerebral Hemorrhage-Induced Secondary Brain Injury in Rats viaSuppressing Apoptosis, Inflammation, Oxidative Stress, DNA Damage, and Mitochondria Injury.

Transl Stroke Res. 2018 Feb;9(1):74-91. (IF 5.78)

391. Li J, Zhou Q, Yang T, Li Y, Zhang Y, Wang J, Jiao Z.

SGK1 inhibits PM2.5-induced apoptosis and oxidativestress in human lung alveolar epithelialA549 cells.

BIOCHEM BIOPH RES CO. 2018 Feb 19;496(4):1291-1295. (IF 2.985)

392. Wang P, Han J, Wei M, Xu Y, Zhang G, Zhang H, Shi L, Liu X, Hamblin MR, Wang X.

Remodeling of dermal collagen in photoaged skin using low-dose 5-aminolevulinic acidphotodynamic therapy occurs via the TGF-β pathway.

J Biophotonics. 2018 Feb 12. (IF 3.032)

393. You P, Wu H, Deng M, Peng J, Li F, Yang Y.

Brevilin A induces apoptosis and autophagy of colon adenocarcinoma cell CT26 viamitochondrial pathway and PI3K/AKT/mTOR inactivation.

Biomed Pharmacother. 2018 Feb;98:619-625. (IF 4.545)

394. Yu W, Ye M, Zhu J, Wang Y, Liang C, Tang J, Tao H, Shen Y.

Zinc phthalocyanine encapsulated in polymer micelles asa potent photosensitizer forthe photodynamic therapy of osteosarcoma.

Nanomedicine. 2018 Feb 17. pii: S1549-9634(18)30037-6. (IF 4.717)

395. He B, Wu F, Fan L, Li XH, Liu Y, Liu YJ, Ding WJ, Deng M, Zhou Y.

Carboxymethylated chitosan protects Schwann cells against hydrogen peroxide-inducedapoptosis by inhibiting oxidative stress and mitochondria dependent pathway.

Eur J Pharmacol. 2018 Feb 17;825:48-56. (IF 3.263)

396. Li Y, Liu Q, Sun J, Wang J, Liu X, Gao J.

Mitochondrial protective mechanism of simvastatin protects against amyloid β peptide-inducedinjury in SH-SY5Y cells.

Int J Mol Med. 2018 Feb 5. (IF 3.098)

397. Chi X, Su P, Bi D, Tai Z, Li Y, Pang Y, Li Q.

Lamprey immune protein-1 (LIP-1)from Lampetra japonica induces cell cycle arrest and celldeath in HeLa cells.

FISH SHELLFISH IMMUN. 2018 Feb 2;75:295-300. (IF 3.298)

398. Guan Y, Tan Y, Liu W, Yang J, Wang D, Pan D, Sun Y, Zheng C.

NF-E2-Related Factor 2 Suppresses Intestinal Fibrosis by Inhibiting Reactive Oxygen Species-Dependent TGF-β1/SMADs Pathway.

DIGEST DIS SCI. 2018 Feb;63(2):366-380. (IF 2.751)

399. Guo W, Liu X, Li J, Shen Y, Zhou Z, Wang M, Xie Y, Feng X, Wang L, Wu X.

Prdx1 alleviates cardiomyocyte apoptosis through ROS-activated MAPK pathway during myocardial ischemia/reperfusion injury.

Int J Biol Macromol. 2018 Feb 2;112:608-615. (IF 5.162)

400. Yang Y, Tang X, Hao F, Ma Z, Wang Y, Wang L, Gao Y

Bavachin Induces Apoptosis through Mitochondrial Regulated ER Stress Pathway in HepG2 Cells.

Biol Pharm Bull. 2018 Feb 1;41(2):198-207. (IF 1.863)

401. Deng X, Huang W, Peng J, Zhu TT, Sun XL, Zhou XY, Yang H, Xiong JF, He HQ, Xu YH, He YZ

Irisin Alleviates Advanced Glycation End Products-Induced Inflammation and Endothelial Dysfunction via Inhibiting ROS-NLRP3 Inflammasome Signaling.

Inflammation. 2018 Feb 41(1):260-275. (IF 3.212)

402. Lei X, Muscat JE, Zhang B, Sha X, Xiu G

Differentially DNA methylation changes induced in vitro by traffic-derived nanoparticulate matter.

Toxicology. 2018 Feb 15 395:54-62. (IF 4.099)

403. Zhou L, Huang W, Xu Y, Gao C, Zhang T, Guo M, Liu Y, Ding J, Qin L, Xu Z, Long Y, Xu Y

Sweet Taste Receptors Mediated ROS-NLRP3 Inflammasome Signaling Activation: Implications for Diabetic Nephropathy.

J Diabetes Res. 2018 Feb 20 2018:7078214. (IF 2.965)

404. Yang LL, Zhao Y, Luo SM, Ma JY, Ge ZJ, Shen W, Yin S.

Toxic effects and possible mechanisms of hydrogensulfide and/or ammonia on porcine oocytematuration in vitro.

Toxicol Lett. 2018 Mar 15;285:20-26. (IF 3.569)

405. Chen J, Lou Q, He L, Wen C, Lin M, Zhu Z, Wang F, Huang L, Lan W, Iwamoto A, Yang X, Liu H.

Reduced-gliotoxin induces ROS-mediated anoikis in human colorectal cancer cells.

Int J Oncol. 2018 Mar;52(3):1023-1032. (IF 3.899)

406. Zhang L, Liu J, Zhou F, Wang W, Chen N.

PGC-1α ameliorates kidney fibrosis in mice with diabetic kidney disease throughan antioxidativemechanism.

Mol Med Rep. 2018 Mar;17(3):4490-4498. (IF 2.1)

407. Xu S, Xiao Y, Zeng S, Zou Y, Qiu Q, Huang M, Zhan Z, Liang L, Yang X, Xu H

Piperlongumine inhibits the proliferation, migration and invasion of fibroblast-like synoviocytes from patients with rheumatoid arthritis.

Inflamm Res. 2018 Mar;67(3):233-243. (IF 3.174)

408. Wang R, Deng D, Shao N, Xu Y, Xue L, Peng Y, Liu Y, Zhi F

Evodiamine activates cellular apoptosis through suppressing PI3K/AKT and activating MAPK in glioma.

ONCOTARGETS THER. 2018 Mar 2;11:1183-1192. (IF 3.337)

409. Zhang L, Liu J, Zhou F, Wang W, Chen N

PGC-1α ameliorates kidney fibrosis in mice with diabetic kidney disease through an antioxidative mechanism.

Mol Med Rep. 2018 Mar 17(3):4490-4498. (IF 2.1)

410. Wu D, Li D, Liu Z, Liu X, Zhou S, Duan H

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Oncol Lett. 2018 Mar 15(3):3676-3684. (IF 2.311)

411. Luo CQ, Zhou YX, Zhou TJ, Xing L, Cui PF, Sun M, Jin L, Lu N, Jiang HL

Reactive oxygen species-responsive nanoprodrug with quinone methides-mediated GSH depletion for improved chlorambucil breast cancers therapy.

J Control Release. 2018 Mar 28 274:56-68. (IF 7.727)

412. Yuan SX, Li JL, Xu XK, Chen W, Chen C, Kuang KQ, Wang FY, Wang K, Li FC.

Underlying mechanism ofthe photodynamic activity of hematoporphyrin induced apoptosis in U87 glioma cells.

Int J Mol Med. 2018 Apr;41(4):2288-2296. (IF 3.098)

413. Liu CL, Deng ZY, Du ER, Xu CS

Long non‑coding RNA BC168687 small interfering RNA reduces high glucose and high free fatty acid‑induced expression of P2X7 receptors in satellite glial cells.

Mol Med Rep. 2018 Apr;17(4):5851-5859. (IF 2.1)

414. Li Y, Zhao Y, Cheng M, Qiao Y, Wang Y, Xiong W, Yue W

Suppression of microRNA-144-3p attenuates oxygen-glucose deprivation/reoxygenation-induced neuronal injury by promoting Brg1/Nrf2/ARE signaling.

J BIOCHEM MOL TOXIC. 2018 Apr 32(4):e22044. (IF 3.606)

415. Qing X, Shao Z, Lv X, Pu F, Gao F, Liu L, Shi D

Anticancer effect of (S)-crizotinib on osteosarcoma cells by targeting MTH1 and activating reactive oxygen species.

ANTI-CANCER DRUG. 2018 Apr 29(4):341-352. (IF 2.26)

416. Dong S, Shi H, Zhang X, Chen X, Cao D, Mao C, Gao X, Wang L

Difunctional bacteriophage conjugated with photosensitizers for Candida albicans-targeting photodynamic inactivation.

INT J NANOMED. 2018 Apr 11 13:2199-2216. (IF 5.115)

417. Jia Z, Wang M, Wang X, Wang L, Qiu L, Song L.

Transcriptome sequencing reveals the involvement of reactive oxygen species inthe hematopoiesis from Chinese mitten crab Eriocheir sinensis.

Dev Comp Immunol. 2018 May;82:94-103. (IF 3.192)

418. Zhang JX, Qu XL, Chu P, Xie DJ, Zhu LL, Chao YL, Li L, Zhang JJ, Chen SL

Low shear stress induces vascular eNOS uncoupling via autophagy-mediated eNOS phosphorylation.

BBA-MOL CELL RES. 2018 May;1865(5):709-720. (IF 4.105)

419. Che Z, Liu F, Zhang W, McGrath M, Hou D, Chen P, Song C, Yang D

Targeting CAND1 promotes caspase-8/RIP1-dependent apoptosis in liver cancer cells.

Am J Transl Res. 2018 May 15;10(5):1357-1372. eCollection 2018. (IF 3.375)

420. Chen S, Fan B.

Myricetin protects cardiomyocytes from LPS-induced injury.

Herz. 2018 May 43(3):265-274. (IF 1.033)

421. Cong L, Yang S, Zhang Y, Cao J, Fu X

DFMG attenuates the activation of macrophages induced by co‑culture with LPC‑injured HUVE‑12 cells via the TLR4/MyD88/NF‑κB signaling pathway.

Int J Mol Med. 2018 May 41(5):2619-2628. (IF 3.098)

422. Gao J, Zhao G, Li W, Zhang J, Che Y, Song M, Gao S, Zeng B, Wang Y

MiR-155 targets PTCH1 to mediate endothelial progenitor cell dysfunction caused by high glucose.

Exp Cell Res. 2018 May 1 366(1):55-62. (IF 3.383)

423. Chang X, Lu K, Wang L, Lv M, Fu W

Astraglaus polysaccharide protects diabetic cardiomyopathy by activating NRG1/ErbB pathway.

Biosci Trends. 2018 May 13 12(2):149-156. (IF 1.553)

424. Tang P, Gu JM, Xie ZA, Gu Y, Jie ZW, Huang KM, Wang JY, Fan SW, Jiang XS, Hu ZJ

Honokiol alleviates the degeneration of intervertebral disc via suppressing the activation of TXNIP-NLRP3 inflammasome signal pathway.

FREE RADICAL BIO MED. 2018 May 20 120:368-379. (IF 6.17)

425. Li J, Wu DD, Zhang JX, Wang J, Ma JJ, Hu X, Dong WG

Mitochondrial pathway mediated by reactive oxygen species involvement in α-hederin-induced apoptosis in hepatocellular carcinoma cells.

WORLD J GASTROENTERO. 2018 May 7 24(17):1901-1910. (IF 3.665)

426. Wang Y, Xu H, Lu Z, Yu X, Lv C, Tian Y, Sui D

Pseudo-Ginsenoside Rh2 induces A549 cells apoptosis via the Ras/Raf/ERK/p53 pathway.

Exp Ther Med. 2018 Jun;15(6):4916-4924. (IF 1.785)

427. Wang X, Chen B, Sun J, Jiang Y, Zhang H, Zhang P, Fei B, Xu Y

Iron-induced oxidative stress stimulates osteoclast differentiation via NF-κB signaling pathway in mouse model.

Metabolism. 2018 Jun 83:167-176. (IF 6.159)

428. Li J, Zhou Q, Liang Y, Pan W, Bei Y, Zhang Y, Wang J, Jiao Z

miR-486 inhibits PM2.5-induced apoptosis and oxidative stress in human lung alveolar epithelial A549 cells.

Ann Transl Med. 2018 Jun 6(11):209. (IF 3.297)

429. Han A, Zou L, Gan X, Li Y, Liu F, Chang X, Zhang X, Tian M, Li S, Su L, Sun Y

ROS generation and MAPKs activation contribute to the Ni-induced testosterone synthesis disturbance in rat Leydig cells.

Toxicol Lett. 2018 Jun 15 290:36-45. (IF 3.569)

430. Yang Y, Wang Y, Kong Y, Zhang X, Zhang H, Gang Y, Bai L

Carnosine Prevents Type 2 Diabetes-Induced Osteoarthritis Through the ROS/NF-κB Pathway.

Front Pharmacol. 2018 Jun 6 9:598. (IF 4.225)

431. Tang X, Wu S, Shen L, Wei Y, Cao X, Wang Y, Long C, Zhou Y, Li D, Huang F, Liu B, Wei G

Di-(2-ethylhexyl) phthalate (DEHP)-induced testicular toxicity through Nrf2-mediated Notch1 signaling pathway in Sprague-Dawley rats.

Environ Toxicol. 2018 Jul;33(7):720-728. (IF 3.118)

432. Wang D, Lou X, Jiang XM, Yang C, Liu XL, Zhang N

Quercetin protects against inflammation, MMP‑2 activation and apoptosis induction in rat model of cardiopulmonary resuscitation through modulating Bmi‑1 expression.

Mol Med Rep. 2018 Jul;18(1):610-616. (IF 2.1)

433. Zhao L, Dong M, Wang D, Ren M, Zheng Y, Zheng H, Li C, Gao H

Characteristic Metabolic Alterations Identified in Primary Neurons Under High Glucose Exposure.

Front Cell Neurosci. 2018 Jul 17;12:207. (IF 3.921)

434. Zheng T, Yang X, Li W, Wang Q, Chen L, Wu D, Bian F, Xing S, Jin S

Salidroside Attenuates High-Fat Diet-Induced Nonalcoholic Fatty Liver Disease via AMPK-Dependent TXNIP/NLRP3 Pathway.

Oxid Med Cell Longev. 2018 Jul 22;2018:8597897. (IF 5.076)

435. Yang L, He Z, Yao J, Tan R, Zhu Y, Li Z, Guo Q, Wei L.

Regulation of AMPK-related glycolipid metabolism imbalances redox homeostasis and inhibits anchorage independent growth in human breast cancer cells.

Redox Biol. 2018 Jul 17:180-191. (IF 9.986)

436. Du XJ, Lu JM

MiR-135a represses oxidative stress and vascular inflammatory events via targeting toll-like receptor 4 in atherogenesis.

J Cell Biochem. 2018 Jul 119(7):6154-6161. (IF 4.237)

437. Tian D, Sha Y, Lu JM, Du XJ

MiR-370 inhibits vascular inflammation and oxidative stress triggered by oxidized low-density lipoprotein through targeting TLR4.

J Cell Biochem. 2018 Jul 119(7):6231-6237. (IF 4.237)

438. Zhou K, Cheng R, Liu B, Wang L, Xie H, Zhang C

Eupatilin ameliorates dextran sulphate sodium-induced colitis in mice partly through promoting AMPK activation.

Phytomedicine. 2018 Jul 15 46:46-56. (IF 4.268)

439. Wu L, Ye M, Zhang J

Vincamine prevents lipopolysaccharide induced inflammation and oxidative stress via thioredoxin reductase activation in human corneal epithelial cells.

Am J Transl Res. 2018 Jul 15 10(7):2195-2204. eCollection 2018. (IF 3.375)

440. Liu Y, Wang N, Zhang S, Liang Q

Autophagy protects bone marrow mesenchymal stem cells from palmitate‑induced apoptosis through the ROS‑JNK/p38 MAPK signaling pathways.

Mol Med Rep. 2018 Aug;18(2):1485-1494. (IF 2.1)

441. Lin Y, Tang G, Jiao Y, Yuan Y, Zheng Y, Chen Y, Xiao J, Li C, Chen Z, Cao P

Propionibacterium acnes Induces Intervertebral Disc Degeneration by Promoting iNOS/NO and COX-2/PGE2 Activation via the ROS-Dependent NF-κB Pathway.

Oxid Med Cell Longev. 2018 Aug 19;2018:3692752. (IF 5.076)

442. Zhang M, Wu Y, Wang M, Wang Y, Tausif R, Yang Y

Genistein rescues hypoxia-induced pulmonary arterial hypertension through estrogen receptor and β-adrenoceptor signaling.

J Nutr Biochem. 2018 Aug 58:110-118. (IF 4.873)

443. Zhang X, Feng Y, Wang Y, Wang J, Xiang D, Niu W, Yuan F

Resveratrol ameliorates disorders of mitochondrial biogenesis and dynamics in a rat chronic ocular hypertension model.

Life Sci. 2018 Aug 15 207:234-245. (IF 3.647)

444. Wang S, Hu Y, Yan Y, Cheng Z, Liu T

Sotetsuflavone inhibits proliferation and induces apoptosis of A549 cells through ROS-mediated mitochondrial-dependent pathway.

BMC COMPLEM ALTERN M. 2018 Aug 9 18(1):235. (IF 2.833)

445. Shen M, Cao Y, Jiang Y, Wei Y, Liu H

Melatonin protects mouse granulosa cells against oxidative damage by inhibiting FOXO1-mediated autophagy: Implication of an antioxidation-independent mechanism.

Redox Biol. 2018 Sep;18:138-157. (IF 9.986)

446. Renjun Wang, Jialin Chen, Ning Ding, Meiaoxue Han, Jianguo Wang, Pan Zhang, Xiuxia Liu, Ningning Zheng, Peike Gao

Antialgal Effects of α-Linolenic Acid on Harmful Bloom-Forming Prorocentrum Donghaiense and the Antialgal Mechanisms

ENVIRON SCI POLLUT R. 2018 Sep;25(25):24798-24806. doi: 10.1007/s11356-018-2536-7. (IF 3.056)

447. Jing W, Zhang L, Qin F, Li X, Guo X, Li Y, Qiu C, Zhao Y

Targeting macrophages for cancer therapy disrupts bone homeostasis and impairs bone marrow erythropoiesis in mice bearing Lewis lung carcinoma tumors.

Cell Immunol. 2018 Sep;331:168-177. (IF 4.078)

448. Gao LX, Bian C, Wu Y, Nisar MF, Chen S, Li CM, Yu L, Ji P, Huang E, Zhong JL

Label-free electrochemical sensor to investigate the effect of tocopherol on generation of superoxide ions following UV irradiation.

J Biol Eng. 2018 Sep 12;12:17. (IF 3.429)

449. Yang B, Cheng H, Wang L, Fu J, Zhang G, Guan D, Qi R, Gao X, Zhao R

Protective roles of NRF2 signaling pathway in cobalt chloride-induced hypoxic cytotoxicity in human HaCaT keratinocytes.

TOXICOL APPL PHARM . 2018 Sep 15;355:189-197. (IF 3.616)

450. Zhu Z, Xie Q, Huang Y, Zhang S, Chen Y

Aucubin suppresses Titanium particles‑mediated apoptosis of MC3T3‑E1 cells and facilitates osteogenesis by affecting the BMP2/Smads/RunX2 signaling pathway.

Mol Med Rep. 2018 Sep 18(3):2561-2570. (IF 2.1)

451. Ma J, Yin G, Lu Z, Xie P, Zhou H, Liu J, Yu L

Casticin prevents DSS induced ulcerative colitis in mice through inhibitions of NF-κB pathway and ROS signaling.

Phytother Res. 2018 Sep 32(9):1770-1783. (IF 4.087)

452. Chen DD, Hui LL, Zhang XC, Chang Q

NEAT1 contributes to ox-LDL-induced inflammation and oxidative stress in macrophages through inhibiting miR-128.

J Cell Biochem. 2018 Sep 11 (IF 4.237)

453. Yan G, Zhang L, Feng C, Gong R, Idiiatullina E, Huang Q, He M, Guo S, Yang F, Li Y, Ding F, Ma W, Pavlov V, Han Z, Wang Z, Xu C, Cai B, Yuan Y, Yang L

Blue light emitting diodes irradiation causes cell death in colorectal cancer by inducing ROS production and DNA damage.

INT J BIOCHEM CELL B. 2018 Oct;103:81-88. (IF 3.673)

454. Shen L, Tang X, Wei Y, Long C, Tan B, Wu S, Sun M, Zhou Y, Cao X, Wei G

Vitamin E and vitamin C attenuate Di-(2-ethylhexyl) phthalate-induced blood-testis barrier disruption by p38 MAPK in immature SD rats.

Reprod Toxicol. 2018 Oct;81:17-27. (IF 3.121)

455. Song Y, Li S, Geng W, Luo R, Liu W, Tu J, Wang K, Kang L, Yin H, Wu X, Gao Y, Zhang Y, Yang C

Sirtuin 3-dependent mitochondrial redox homeostasis protects against AGEs-induced intervertebral disc degeneration.

Redox Biol. 2018 Oct;19:339-353. (IF 9.986)

456. Xia W, Zhuang L, Hou M

Role of lincRNA‑p21 in the protective effect of macrophage inhibition factor against hypoxia/serum deprivation‑induced apoptosis in mesenchymal stem cells.

Int J Mol Med. 2018 Oct;42(4):2175-2184. (IF 3.098)

457. Qin SB, Peng DY, Lu JM, Ke ZP

MiR-182-5p inhibited oxidative stress and apoptosis triggered by oxidized low-density lipoprotein via targeting toll-like receptor 4.

J Cell Physiol. 2018 Oct 233(10):6630-6637. (IF 5.546)

458. Wu CY, Zhou ZF, Wang B, Ke ZP, Ge ZC, Zhang XJ

MicroRNA-328 ameliorates oxidized low-density lipoprotein-induced endothelial cells injury through targeting HMGB1 in atherosclerosis.

J Cell Biochem. 2018 Oct 15 (IF 4.237)

459. Wang Y, Deng X, Yu C, Zhao G, Zhou J, Zhang G, Li M, Jiang D, Quan Z, Zhang Y

Synergistic inhibitory effects of capsaicin combined with cisplatin on human osteosarcoma in culture and in xenografts.

J EXP CLIN CANC RES. 2018 Oct 16 37(1):251. (IF 7.068)

460. Wang J, Li M, Cui X, Lv D, Jin L, Khan M, Ma T

Brevilin A promotes oxidative stress and induces mitochondrial apoptosis in U87 glioblastoma cells.

ONCOTARGETS THER. 2018 Oct 16 11:7031-7040. (IF 3.337)

461. Li C, Liu H, Yang Y, Xu X, Lv T, Zhang H, Liu K, Zhang S, Chen Y

N-myristoylation of Antimicrobial Peptide CM4 Enhances Its Anticancer Activity by Interacting With Cell Membrane and Targeting Mitochondria in Breast Cancer Cells.

Front Pharmacol. 2018 Nov 13;9:1297. (IF 4.225)

462. Zhang D, Li Y, Zhang T, Liu J, Jahejo AR, Yang L, Chen P, Ning G, Huo N, Ma H, Yan F, Tian W

Protective effects of zinc and N-acetyl-L-cysteine supplementation against cadmium induced erythrocyte cytotoxicity in Arbor Acres broiler chickens (Gallus gallus domesticus).

ECOTOX ENVIRON SAFE. 2018 Nov 15;163:331-339. (IF 4.872)

463. Jin Y, Yang Q, Liang L, Ding L, Liang Y, Zhang D, Wu B, Yang T, Liu H, Huang T, Shen H, Tu H, Pan Y, Wei Y, Yang Y, Zhou F

Compound kushen injection suppresses human acute myeloid leukaemia by regulating the Prdxs/ROS/Trx1 signalling pathway.

J EXP CLIN CANC RES. 2018 Nov 19;37(1):277. (IF 7.068)

464. Gao X, Guo S, Zhang S, Liu A, Shi L, Zhang Y

Matrine attenuates endoplasmic reticulum stress and mitochondrion dysfunction in nonalcoholic fatty liver disease by regulating SERCA pathway.

J Transl Med. 2018 Nov 20;16(1):319. (IF 4.124)

465. Wu J, Chu Z, Ruan Z, Wang X, Dai T, Hu X

Changes of Intracellular Porphyrin, Reactive Oxygen Species, and Fatty Acids Profiles During Inactivation of Methicillin-Resistant Staphylococcus aureus by Antimicrobial Blue Light.

Front Physiol. 2018 Nov 28;9:1658. (IF 3.367)

466. Cai C, Liu C, Zhao L, Liu H, Li W, Guan H, Zhao L, Xiao J.

Effects of Taxifolin on Osteoclastogenesis in vitro and in vivo.

Front Pharmacol. 2018 Nov 12 9:1286. (IF 4.225)

467. Yang L, Shen Q, Xia Y, Lei X, Peng J

Sevoflurane‑induced neurotoxicity is driven by OXR1 post‑transcriptional downregulation involving hsa‑miR‑302e.

Mol Med Rep. 2018 Nov 18(5):4657-4665. (IF 2.1)

468. Yue Q, Peng Y, Zhao Y, Lu R, Fu Q, Chen Y, Yang Y, Hai L, Guo L, Wu Y

Dual-targeting for brain-specific drug delivery: synthesis and biological evaluation.

Drug Deliv. 2018 Nov 25(1):426-434. (IF 4.902)

469. Zhao Y, Zhao R, Wu J, Wang Q, Pang K, Shi Q, Gao Q, Hu Y, Dong X, Zhang J, Sun J

Melatonin protects against Aβ-induced neurotoxicity in primary neurons via miR-132/PTEN/AKT/FOXO3a pathway.

Biofactors. 2018 Nov 44(6):609-618. (IF 4.734)

470. Liu J, Wang W, Liu X, Wang X, Wang J, Wang Y, Li N, Wang X

Supplementation of cryopreservation medium with TAT-Peroxiredoxin 2 fusion protein improves human sperm quality and function.

Fertil Steril. 2018 Nov 110(6):1058-1066. (IF 6.312)

471. Chen S, Zhou Y, Zhou L, Guan Y, Zhang Y, Han X

Anti-neovascularization effects of DMBT in age-related macular degeneration by inhibition of VEGF secretion through ROS-dependent signaling pathway.

Mol Cell Biochem. 2018 Nov 448(1-2):225-235. (IF 2.795)

472. Liu Y, Xu Z, Ma F, Jia Y, Wang G

Knockdown of TLR4 attenuates high glucose-induced podocyte injury via the NALP3/ASC/Caspase-1 signaling pathway.

Biomed Pharmacother. 2018 Nov 107:1393-1401. (IF 4.545)

473. Guo L, Yang W, Huang Q, Qiang J, Hart JR, Wang W, Hu J, Zhu J, Liu N, Zhang Y

Selenocysteine-Specific Mass Spectrometry Reveals Tissue-Distinct Selenoproteomes and Candidate Selenoproteins.

Cell Chem Biol. 2018 Nov 15 25(11):1380-1388.e4. (IF 7.739)

474. Zhang C, Xie L, Guan F, Cui Y

3H-1,2-dithiole-3-thione protects PC12 cells against amyloid beta 1-42 (Aβ1-42) induced apoptosis via activation of the ERK1/2 pathway.

Life Sci. 2018 Nov 15 213:74-81. (IF 3.647)

475. Xu S, Zhao X, Liu F, Cao Y, Wang B, Wang X, Yin M, Wang Q, Feng X

Crucial role of oxidative stress in bactericidal effect of parthenolide against Xanthomonas oryzae pv. oryzae.

Pest Manag Sci. 2018 Dec;74(12):2716-2723. (IF 3.75)

476. Luo Z, Luo W, Li S, Zhao S, Sho T, Xu X, Zhang J, Xu W, Xu J

Reactive oxygen species mediated placental oxidative stress, mitochondrial content, and cell cycle progression through mitogen-activated protein kinases in intrauterine growth restricted pigs.

Reprod Biol. 2018 Dec;18(4):422-431. (IF 1.862)

477. Wang W, Yang LL, Luo SM, Ma JY, Zhao Y, Shen W, Yin S

Toxic effects and possible mechanisms following malathion exposure in porcine granulosa cells.

ENVIRON TOXICOL CHEM. 2018 Dec;64:172-180. (IF 3.152)

478. Jiani Tan, Liu Li, Wenjing Shi, Dongdong Sun, Changliang Xu, Yunjie Miao, Huisen Fan, Jianrong Liu, Haibo Cheng, Mianhua Wu, Weixing Shen

Protective Effect of 2-Hydroxymethyl Anthraquinone From Hedyotis Diffusa Willd in Lipopolysaccharide-Induced Acute Lung Injury Mediated by TLR4-NF-κB Pathway

Inflammation. 2018 Dec;41(6):2136-2148. doi: 10.1007/s10753-018-0857-9. (IF 3.212)

479. Wu Z, Wang Y, Meng X, Wang X, Li Z, Qian S, Wei Y, Shu L, Ding Y, Wang P, Peng Y

Total C-21 steroidal glycosides, isolated from the root tuber of Cynanchum auriculatum Royle ex Wight, attenuate hydrogen peroxide-induced oxidative injury and inflammation in L02 cells.

Int J Mol Med. 2018 Dec 42(6):3157-3170. (IF 3.098)

480. Yang Y, Gu H, Sun Q, Wang J

Effects of Christensenella minuta lipopolysaccharide on RAW 264.7 macrophages activation.

MICROB PATHOGENESIS. 2018 Dec 125:411-417. (IF 2.914)

481. Gao J, Wang Y, Li W, Zhang J, Che Y, Cui X, Sun B, Zhao G

Loss of histone deacetylase 2 inhibits oxidative stress induced by high glucose via the HO-1/SIRT1 pathway in endothelial progenitor cells.

Gene. 2018 Dec 15 678:1-7. (IF 2.984)

482. Zhao Y, Shang F, Shi W, Zhang J, Zhang J, Liu X, Li B, Hu X, Wang L

Angiotensin II Receptor Type 1 Antagonists Modulate Vascular Smooth Muscle Cell Proliferation and Migration via AMPK/mTOR.

Cardiology. 2019 143(1):1-10. (IF 1.791)

483. Xin Hu, Xiaofang Wu, Bo Zhao, Yongyi Wang

Scutellarin Protects Human Retinal Pigment Epithelial Cells Against Hydrogen Peroxide (H 2 O 2)-induced Oxidative Damage

Cell Biosci. 2019 Jan 21;9:12. doi: 10.1186/s13578-019-0276-0. (IF 5.026)

484. Wu Y, Li ZC, Yao LQ, Li M, Tang M

Schisandrin B alleviates acute oxidative stress via modulation of the Nrf2/Keap1-mediated antioxidant pathway.

Appl Physiol Nutr Metab. 2019 Jan 44(1):1-6.

485. Peng Y, Zhang R, Yang X, Zhang Z, Kang N, Bao L, Shen Y, Yan H, Zheng F

Ginsenoside Rg3 suppresses the proliferation of prostate cancer cell line PC3 through ROS-induced cell cycle arrest.

Oncol Lett. 2019 Jan 17(1):1139-1145. (IF 2.311)

486. Cui B, Zhang S, Wang Y, Guo Y

Farrerol attenuates β-amyloid-induced oxidative stress and inflammation through Nrf2/Keap1 pathway in a microglia cell line.

Biomed Pharmacother. 2019 Jan 109:112-119. (IF 4.545)

487. Qiu M, Zhang S, Ke L, Tang H, Zeng X, Liu J

JS-K enhances chemosensitivity of prostate cancer cells to Taxol via reactive oxygen species activation.

Oncol Lett. 2019 Jan 17(1):757-764. (IF 2.311)

488. Zhong KL, Lu MY, Liu F, Mei Y, Zhang XJ, Zhang H, Zan J, Sun XO, Tan W

Isosteviol Sodium Protects Neural Cells Against Hypoxia-Induced Apoptosis Through Inhibiting MAPK and NF-κB Pathways.

J STROKE CEREBROVASC . 2019 Jan 28(1):175-184. (IF 1.598)

489. Zhou F, Liao F, Chen L, Liu Y, Wang W, Feng S

The size-dependent genotoxicity and oxidative stress of silica nanoparticles on endothelial cells.

ENVIRON SCI POLLUT R. 2019 Jan 26(2):1911-1920. (IF 3.056)

490. Wu G, Zhang Z, Chen X, Yu Q, Ma X, Liu L

Chemosensitization effect of cerium oxide nanosheets by suppressing drug detoxification and efflux.

ECOTOX ENVIRON SAFE. 2019 Jan 15 167:301-308. (IF 4.872)

491. Cheng J, Yang HL, Gu CJ, Liu YK, Shao J, Zhu R, He YY, Zhu XY, Li MQ

Melatonin restricts the viability and angiogenesis of vascular endothelial cells by suppressing HIF-1α/ROS/VEGF.

Int J Mol Med. 2019 Feb 43(2):945-955. (IF 3.098)

492. Zhao H, Wang R, Ye M, Zhang L

Genipin protects against H2O2-induced oxidative damage in retinal pigment epithelial cells by promoting Nrf2 signaling.

Int J Mol Med. 2019 Feb 43(2):936-944. (IF 3.098)

493. Luo Z, Xu X, Sho T, Zhang J, Xu W, Yao J, Xu J

ROS-induced autophagy regulates porcine trophectoderm cell apoptosis, proliferation, and differentiation.

AM J PHYSIOL-CELL PH. 2019 Feb 1 316(2):C198-C209. (IF 3.485)

494. Wang R, Dong Z, Lan X, Liao Z, Chen M

Sweroside Alleviated LPS-Induced Inflammation via SIRT1 Mediating NF-κB and FOXO1 Signaling Pathways in RAW264.7 Cells.

Molecules. 2019 Mar 1 24(5). pii: E872. (IF 3.267)

495. He YT, Yang LL, Zhao Y, Shen W, Yin S, Sun QY

Fenoxaprop-ethyl affects mouse oocyte quality and the underlying mechanisms.

Pest Manag Sci. 2019 Mar;75(3):844-851. (IF 3.75)

496. Liu Y, Han J, Zhou Z, Li D

Tangeretin inhibits streptozotocin-induced cell apoptosis via regulating NF-κB pathway in INS-1 cells.

J Cell Biochem. 2019 Mar 120(3):3286-3293. (IF 4.237)

497. Shen X, Guo M, Yu H, Liu D, Lu Z, Lu Y

Propionibacterium acnes related anti-inflammation and skin hydration activities of madecassoside, a pentacyclic triterpene saponin from Centella asiatica.

BIOSCI BIOTECH BIOCH. 2019 Mar 83(3):561-568. (IF 1.516)

498. Chen M, Du D, Zheng W, Liao M, Zhang L, Liang G, Gong M

Small hepatitis delta antigen selectively binds to target mRNA in hepatic cells: a potential mechanism by which hepatitis D virus downregulates glutathione S-transferase P1 and induces liver injury an

Biochem Cell Biol. 2019 Apr 97(2):130-139. (IF 2.46)

499. Wu B, Wu X, Liu S, Wang Z, Chen L

Size-dependent effects of polystyrene microplastics on cytotoxicity and efflux pump inhibition in human Caco-2 cells.

Chemosphere. 2019 Apr 221:333-341. (IF 5.778)

500. Zhang L, Wang H, Zhou X, Mao L, Ding K, Hu Z

Role of mitochondrial calcium uniporter-mediated Ca2+ and iron accumulation in traumatic brain injury.

J Cell Mol Med. 2019 Apr 23(4):2995-3009. (IF 4.486)

501. Liu JJ, Zhang W, Wang SS, Jia ZQ, Shi YH, Yang L, Shi RL

Effects of chain length of saturated fatty acids on Aβ generation in SH-SY5Y cells.

Neurosci Lett. 2019 Apr 17 698:169-172. (IF 2.274)

502. Jiao Y, Niu T, Liu H, Tay FR, Chen JH

Protection against HEMA-Induced Mitochondrial Injury In Vitro by Nrf2 Activation.

Oxid Med Cell Longev. 2019 Apr 7 2019:3501059. (IF 5.076)

503. Yin J, Xia W, Wu M, Zhang Y, Huang S, Zhang A, Jia Z

Inhibition of mitochondrial complex I activity attenuates neointimal hyperplasia by inhibiting smooth muscle cell proliferation and migration.

CHEM-BIOL INTERACT. 2019 May 1 304:73-82. (IF 3.723)

504. Liu X, Zhao P, Wang X, Wang L, Zhu Y, Gao W

Triptolide Induces Glioma Cell Autophagy and Apoptosis via Upregulating the ROS/JNK and Downregulating the Akt/mTOR Signaling Pathways.

Front Oncol. 2019 May 14 9:387. (IF 4.848)

505. Zhang H, Wang W, Du Q

Andrographolide attenuates bupivacaine-induced cytotoxicity in SH-SY5Y cells through preserving Akt/mTOR activity.

DRUG DES DEV THER. 2019 May 16 13:1659-1666. (IF 3.216)

506. Yang L, Guan G, Lei L, Liu J, Cao L, Wang X

Oxidative and endoplasmic reticulum stresses are involved in palmitic acid-induced H9c2 cell apoptosis.

BIOSCIENCE REP. 2019 May 21 39(5). pii: BSR20190225. (IF 2.942)

507. Kong C, Hao M, Chen X, Zhao X, Wang Y, Li J, Gao Y, Zhang H, Yang B, Jiang J

NF-κB inhibition promotes apoptosis in androgen-independent prostate cancer cells by the photothermal effect via the IκBα/AR signaling pathway.

BIOMATER SCI-UK. 2019 May 28 7(6):2559-2570. (IF 6.183)

508. Li WD, Yu S, Luo SM, Shen W, Yin S, Sun QY

Melatonin defends mouse oocyte quality from benzo[ghi]perylene-induced deterioration.

J Cell Physiol. 2019 May;234(5):6220-6229. (IF 5.546)

509. Yang Y, Wang Y, Kong Y, Zhang X, Zhang H, Gang Y, Bai L

Mechanical stress protects against osteoarthritis via regulation of the AMPK/NF-κB signaling pathway.

J Cell Physiol. 2019 Jun 234(6):9156-9167. (IF 5.546)

510. Wan GX, Cheng L, Qin HL, Zhang YZ, Wang LY, Zhang YG

MiR-15b-5p is Involved in Doxorubicin-Induced Cardiotoxicity via Inhibiting Bmpr1a Signal in H9c2 Cardiomyocyte.

Cardiovasc Toxicol. 2019 Jun 19(3):264-275. (IF 2.284)

511. Li M, Fang XZ, Zheng YF, Xie YB, Ma XD, Liu XT, Xia Y, Shao DH

Transient receptor potential vanilloid 4 is a critical mediator in LPS mediated inflammation by mediating calcineurin/NFATc3 signaling.

BIOCHEM BIOPH RES CO. 2019 Jun 11 513(4):1005-1012. (IF 2.985)

512. Zheng Y, Liu W, Chen Y, Li C, Jiang H, Wang X

Conjugating gold nanoclusters and antimicrobial peptides: From aggregation-induced emission to antibacterial synergy.

J COLLOID INTERF SCI. 2019 Jun 15 546:1-10. (IF 7.489)

513. Liao X, Fan Y, Hou J, Chen X, Xu X, Yang Y, Shen J, Mi P, Huang X, Zhang W, Cao H, Hong X, Hu T, Zhan YY

Identification of Chaetocin as a Potent non-ROS-mediated Anticancer Drug Candidate for Gastric Cancer.

J Cancer. 2019 Jun 9 10(16):3678-3690. (IF 3.565)

514. Wang J, Wang X, Li ZZ, Guo F, Ding CZ, Zhao YY, Liu YL, Ma XJ, Li C, Wu LN, Qin Q, Zhao SY, Zhao D, Hao X, Wang SJ, Qin GJ

The apoptosis and GLP-1 hyposecretion induced by LPS via RIP/ROS/mTOR pathway in GLUTag cells.

Biochimie. 2019 Jul 162:229-238. (IF 3.413)

515. Wang Y, Yu C, Zhang H

Lipopolysaccharides-mediated injury to chondrogenic ATDC5 cells can be relieved by Sinomenine via downregulating microRNA-192.

Phytother Res. 2019 Jul 33(7):1827-1836. (IF 4.087)

516. Pang Q, Li Y, Meng L, Li G, Luo Z, Fan R

Neurotoxicity of BPA, BPS, and BPB for the hippocampal cell line (HT-22): An implication for the replacement of BPA in plastics.

Chemosphere. 2019 Jul 226:545-552. (IF 5.778)

517. Liu Y, Shao E, Zhang Z, Yang D, Li G, Cao H, Huang H

A Novel Indolizine Derivative Induces Apoptosis Through the Mitochondria p53 Pathway in HepG2 Cells.

Front Pharmacol. 2019 Jul 10 10:762. (IF 4.225)

518. Li H, Wang Y, Hu X, Ma B, Zhang H

Thymosin beta 4 attenuates oxidative stress-induced injury of spinal cord-derived neural stem/progenitor cells through the TLR4/MyD88 pathway.

Gene. 2019 Jul 30 707:136-142. (IF 2.984)

519. Zheng H, Zhang M, Luo H, Li H

Isoorientin alleviates UVB-induced skin injury by regulating mitochondrial ROS and cellular autophagy.

BIOCHEM BIOPH RES CO. 2019 Jul 5 514(4):1133-1139. (IF 2.985)

520. Hu X, Ma R, Fu W, Zhang C, Du X

LncRNA UCA1 sponges miR-206 to exacerbate oxidative stress and apoptosis induced by ox-LDL in human macrophages.

J Cell Physiol. 2019 Aug 234(8):14154-14160. (IF 5.546)

521. Wang Y, Mao X, Chen H, Feng J, Yan M, Wang Y, Yu Y

Dexmedetomidine alleviates LPS-induced apoptosis and inflammation in macrophages by eliminating damaged mitochondria via PINK1 mediated mitophagy.

Int Immunopharmacol. 2019 Aug 73:471-481. (IF 3.943)

522. An Q, Peng W, Cheng Y, Lu Z, Zhou C, Zhang Y, Su J

Melatonin supplementation during in vitro maturation of oocyte enhances subs equent development of bovine cloned embryos.

J Cell Physiol. 2019 Aug 234(10):17370-17381. (IF 5.546)

523. Zhang M, Xu Y, Jiang L

Irisin attenuates oxidized low-density lipoprotein impaired angiogenesis through AKT/mTOR/S6K1/Nrf2 pathway.

J Cell Physiol. 2019 Aug 234(10):18951-18962. (IF 5.546)

524. Ma X, Cheng F, Yuan K, Jiang K, Zhu T

Lipid storage droplet protein 5 reduces sodium palmitate‑induced lipotoxicity in human normal liver cells by regulating lipid metabolism‑related factors.

Mol Med Rep. 2019 Aug 20(2):879-886. (IF 2.1)

525. Li Z, Huang L, Wei L, Hou Z, Ye W, Huang S

Chaetocin induces caspase-dependent apoptosis in ovarian cancer cells via the generation of reactive oxygen species.

Oncol Lett. 2019 Aug 18(2):1915-1921. (IF 2.311)

526. Ge LN, Yan L, Li C, Cheng K

Bavachinin exhibits antitumor activity against non‑small cell lung cancer by targeting PPARγ.

Mol Med Rep. 2019 Sep 20(3):2805-2811. (IF 2.1)

527. Xiang J, Zhang J, Cai X, Yang F, Zhu W, Zhang W, Cai M, Yu Z, Li X, Wu T, Wang G, Cai D

Bilobalide protects astrocytes from oxygen and glucose deprivation-induced oxidative injury by upregulating manganese superoxide dismutase.

Phytother Res. 2019 Sep 33(9):2329-2336. (IF 4.087)

528. Zhang B, Wang X, Deng J, Zheng H, Liu W, Chen S, Tian J, Wang F

p53-dependent upregulation of miR-16-2 by sanguinarine induces cell cycle arrest and apoptosis in hepatocellular carcinoma.

Cancer Lett. 2019 Sep 10 459:50-58. (IF 7.36)

529. Chao Chen, Meng-Yu Ling, Fan-Hong Lin, Ling Xu, Zheng Mei Lv

Melatonin Appears to Protect Against Steroidogenic Collapse in Both Mice Fed With High-Fat Diet and H 2 O 2 -Treated TM3 Cells

Andrologia. 2019 Sep;51(8):e13323. doi: 10.1111/and.13323. (IF 1.951)

530. Zhang C, He LJ, Zhu YB, Fan QZ, Miao DD, Zhang SP, Zhao WY, Liu XP

Piperlongumine Inhibits Akt Phosphorylation to Reverse Resistance to Cisplatin in Human Non-Small Cell Lung Cancer Cells via ROS Regulation.

Front Pharmacol. 2019 Oct 11 10:1178. (IF 4.225)

531. Wang Y, Zhao CS

Sigma-1 receptor activation ameliorates LPS-induced NO production and ROS formation through the Nrf2/HO-1 signaling pathway in cultured astrocytes.

Neurosci Lett. 2019 Oct 15 711:134387. (IF 2.274)

532. Yuan Z, Liang Z, Yi J, Chen X, Li R, Wu J, Sun Z

Koumine Promotes ROS Production to Suppress Hepatocellular Carcinoma Cell Proliferation Via NF-κB and ERK/p38 MAPK Signaling.

Biomolecules. 2019 Oct 2 9(10). pii: E559. (IF 4.082)

533. Liu Y, Lei H, Ma J, Deng H, He P, Dong W

α-Hederin Increases The Apoptosis Of Cisplatin-Resistant Gastric Cancer Cells By Activating Mitochondrial Pathway In Vivo And Vitro.

ONCOTARGETS THER. 2019 Oct 23 12:8737-8750. (IF 3.337)

534. Piao X, Liu Z, Li Y, Yao D, Sun L, Wang B, Ma Y, Wang L, Zhang Y

Investigation of the effect for bisphenol A on oxidative stress in human hepatocytes and its interaction with catalase.

SPECTROCHIM ACTA A. 2019 Oct 5 221:117149. (IF 3.232)

535. Du X, Wu Z, Xu Y, Liu Y, Liu W, Wang T, Li C, Zhang C, Yi F, Gao L, Liang X, Ma C

Increased Tim-3 expression alleviates liver injury by regulating macrophage activation in MCD-induced NASH mice.

Cell Mol Immunol. 2019 Nov 16(11):878-886. (IF 8.484)

536. Huang L, Cai C, Dang W, Lu JH, Hu GF, Gu J

Propyl isothiocyanate induces apoptosis in gastric cancer cells by oxidative stress via glutathione depletion.

Oncol Lett. 2019 Nov 18(5):5490-5498. (IF 2.311)

537. Pang D, Li C, Yang C, Zou Y, Feng B, Li L, Liu W, Geng Y, Luo Q, Chen Z, Huang C

Polyphyllin VII Promotes Apoptosis and Autophagic Cell Death via ROS-Inhibited AKT Activity, and Sensitizes Glioma Cells to Temozolomide.

Oxid Med Cell Longev. 2019 Nov 14 2019:1805635. (IF 5.076)

538. Wang X, Bian Y, Zhang R, Liu X, Ni L, Ma B, Zeng R, Zhao Z, Song X, Liu C

Melatonin alleviates cigarette smoke-induced endothelial cell pyroptosis through inhibiting ROS/NLRP3 axis.

BIOCHEM BIOPH RES CO. 2019 Nov 5 519(2):402-408. (IF 2.985)

539. Ran K, Yang Z, Zhao Y, Wang X.

Transmural pressure drives proliferation of human arterial smooth muscle cells via mechanism associated with NADPH oxidase and Survivin.

Microvasc Res. 2019 Nov 126:103905. (IF 2.73)

540. Zhang P, Wang T, Zhang D, Zhang Z, Yuan S, Zhang J, Cao J, Li H, Li X, Shen H, Chen G

Exploration of MST1-Mediated Secondary Brain Injury Induced by Intracerebral Hemorrhage in Rats via Hippo Signaling Pathway.

Transl Stroke Res. 2019 Dec 10(6):729-743. (IF 5.78)

541. Liu Y, Yang W, Sun X, Xie L, Yang Y, Sang M, Jiao R

SS31 Ameliorates Sepsis-Induced Heart Injury by Inhibiting Oxidative Stress and Inflammation.

Inflammation. 2019 Dec 42(6):2170-2180. (IF 3.212)

542. Zhang J, He J

CTRP3 inhibits high glucose-induced oxidative stress and apoptosis in retinal pigment epithelial cells.

ARTIF CELL NANOMED B. 2019 Dec 47(1):3758-3764. (IF 3.343)

543. Deng H, Ma J, Liu Y, He P, Dong W

Combining α-Hederin with cisplatin increases the apoptosis of gastric cancer in vivo and in vitro via mitochondrial related apoptosis pathway.

Biomed Pharmacother. 2019 Dec 120:109477. (IF 4.545)

544. Wang D, Zhang Z, Lin L, Liu F, Wang Y, Guo Z, Li Y, Tian H, Chen X

Porphyrin-based covalent organic framework nanoparticles for photoacoustic imaging-guided photodynamic and photothermal combination cancer therapy.

Biomaterials. 2019 Dec 223:119459. (IF 10.317)

545. Cui R, Tian L, Lu D, Li H, Cui J

Exendin-4 Protects Human Retinal Pigment Epithelial Cells from H2O2-Induced Oxidative Damage via Activation of NRF2 Signaling.

Ophthalmic Res. 2019 Dec 20:1-9 (IF 1.961)

546. Li S, Xie A, Li H, Zou X, Zhang Q

A self-assembled, ROS-responsive Janus-prodrug for targeted therapy of inflammatory bowel disease.

J Control Release. 2019 Dec 28 316:66-78. (IF 7.727)

547. Guoyong Lu, Peng Tian, Yongxin Zhu, Xiaohua Zuo, Xiaoqiang Li

LncRNA XIST knockdown ameliorates oxidative low-density lipoprotein-induced endothelial cells injury by targeting miR-204-5p/TLR4

J Biosci. 2020;45:52.

548. Meng-Qiao Zhou, E Jin, Jing Wu, Fei Ren, Yu-Zhi Yang, Dong-Dong Duan

CTRP12 Ameliorated Lipopolysaccharide-Induced Cardiomyocyte Injury

Chem Pharm Bull (Tokyo). 2020;68(2):133-139. doi: 10.1248/cpb.c19-00646.

549. Xiaopeng Wang, Jing Zhao

Neuroprotective effect of CPCGI on Alzheimer's disease and its mechanism

Mol Med Rep. 2020 Jan;21(1):115-122. doi: 10.3892/mmr.2019.10835. (IF 2.1)

550. Ruiqian Li, Libing Hu, Chen Hu, Qiling Wang, Yonghong Lei, Bin Zhao

Myricitrin protects against cisplatin-induced kidney injury by eliminating excessive reactive oxygen species

Int Urol Nephrol. 2020 Jan;52(1):187-196. doi: 10.1007/s11255-019-02334-8. (IF 1.843)

551. JiaYi Xu, Yingjie Sun, Jie Lu

Knockdown of Long Noncoding RNA (lncRNA) AK094457 Relieved Angiotensin II Induced Vascular Endothelial Cell Injury

Med Sci Monit. 2020 Feb 6;26:e919854. doi: 10.12659/MSM.919854.

552. Xin Wang, Yanan Zhang, Shuai Han, Hongshen Chen, Chen Chen, Lingling Ji, Bihu Gao

Overexpression of miR‑30c‑5p reduces cellular cytotoxicity and inhibits the formation of kidney stones through ATG5

Int J Mol Med. 2020 Feb;45(2):375-384. doi: 10.3892/ijmm.2019.4440. (IF 3.098)

553. Zhang J, Wang Q, Wang Q, Guo P, Wang Y, Xing Y, Zhang M, Liu F, Zeng Q

Chrysophanol exhibits anti-cancer activities in lung cancer cell through regulating ROS/HIF-1a/VEGF signaling pathway.

N-S ARCH PHARMACOL. 2020 Mar 393(3):469-480. (IF 2.05)

554. Zhe Lu, Jingcheng Dai, LingLing Zheng, Zhuoran Teng, Qi Zhang, Dongru Qiu, Lirong Song

Disodium 2-oxoglutarate promotes carbon flux into astaxanthin and fatty acid biosynthesis pathways in Haematococcus

Bioresour Technol. 2020 Mar;299:122612. doi: 10.1016/j.biortech.2019.122612.

555. Yang S, Shao S, Huang B, Yang D, Zeng L, Gan Y, Long D, Chen J, Wang J

Tea polyphenols alleviate tri-ortho-cresyl phosphate-induced autophagy of mouse ovarian granulosa cells.

Environ Toxicol. 2020 Apr 35(4):478-486. (IF 3.118)

556. Jiangtao Bai, Yuyang Wang, Jianping Wang, Jianglong Zhai, Feilong He, Guoying Zhu

Irradiation-induced senescence of bone marrow mesenchymal stem cells aggravates osteogenic differentiation dysfunction via paracrine signaling

Am J Physiol Cell Physiol. 2020 May 1;318(5):C1005-C1017. doi: 10.1152/ajpcell.00520.2019.

557. Yue Yang, Yang Wang, Yawei Kong, Xiaoning Zhang, He Zhang, Xinyuan Feng, Ziyuan Wang, Peng Gao, Mingyue Yan, Lunhao Bai, Feng Li

Moderate Mechanical Stimulation Protects Rats against Osteoarthritis through the Regulation of TRAIL via the NF- κ B/NLRP3 Pathway

Oxid Med Cell Longev. 2020 May 23;2020:6196398. doi: 10.1155/2020/6196398. (IF 5.076)

558. Xiangyuan Chen, Jie Qi, Qichao Wu, Hui Jiang, Jing Wang, Wankun Chen, Anrong Mao, Minmin Zhu

High glucose inhibits vascular endothelial Keap1/Nrf2/ARE signal pathway via downregulation of monomethyltransferase SET8 expression

Acta Biochim Biophys Sin (Shanghai). 2020 May 26;52(5):506-516. doi: 10.1093/abbs/gmaa023.

559. Yuhan Yang, Ling Yang, Sheng Jiang, Ting Yang, Jingbin Lan, Yun Lei, Hao Tan, Kejian Pan

HMGB1 mediates lipopolysaccharide-induced inflammation via interacting with GPX4 in colon cancer cells

Cancer Cell Int. 2020 May 29;20:205. doi: 10.1186/s12935-020-01289-6. (IF 4.175)

560. Bi Lin, Ziyuan Jin, Xiang Chen, Li Zhao, Chengwei Weng, Baihui Chen, Yaning Tang, Lina Lin

Necrostatin‑1 protects mice from acute lung injury by suppressing necroptosis and reactive oxygen species

Mol Med Rep. 2020 May;21(5):2171-2181. doi: 10.3892/mmr.2020.11010. (IF 2.1)

561. Sheng Wang, Jiaji Mao, Hong Liu, Shihui Huang, Jiali Cai, Wentao Gui, Jun Wu, Junyao Xu, Jun Shen, Zhiyong Wang

pH-Sensitive nanotheranostics for dual-modality imaging guided nanoenzyme catalysis therapy and phototherapy

J Mater Chem B. 2020 Jun 10;8(22):4859-4869. doi: 10.1039/c9tb02731a. (IF 5.344)

562. Shan Huang, Meng Tan, Feng Guo, Linsha Dong, Zhiming Liu, Ruiying Yuan, Zhuoma Dongzhi, Dong-Sung Lee, Yuefei Wang, Bin Li

Nepeta angustifolia C. Y. Wu improves renal injury in HFD/STZ-induced diabetic nephropathy and inhibits oxidative stress-induced apoptosis of mesangial cells

J Ethnopharmacol. 2020 Jun 12;255:112771. doi: 10.1016/j.jep.2020.112771. (IF 3.69)

563. Xuan Xu, Chu Chen, Wen-Jiang Lu, Yi-Ling Su, Jia-Yu Shi, Yu-Chen Liu, Li Wang, Chen-Xi Xiao, Xiang Wu, Qi Lu

Pyrroloquinoline quinone can prevent chronic heart failure by regulating mitochondrial function

Cardiovasc Diagn Ther. 2020 Jun;10(3):453-469. doi: 10.21037/cdt-20-129.

564. Hua Liu, Xiao-Jian Weng, Jun-Yan Yao, Jun Zheng, Xiang Lv, Xu-Hui Zhou, Hong Jiang, Shi-Tong Li

Neuregulin-1 β Protects the Rat Diaphragm during Sepsis against Oxidative Stress and Inflammation by Activating the PI3K/Akt Pathway

Oxid Med Cell Longev. 2020 Jul 19;2020:1720961. doi: 10.1155/2020/1720961. (IF 5.076)

565. Xing-Hua Wang, Shen Yin, Xiang-Hong Ou, Shi-Ming Luo

Increase of mitochondria surrounding spindle causes mouse oocytes arrested at metaphase I stage

Biochem Biophys Res Commun. 2020 Jul 5;527(4):1043-1049. doi: 10.1016/j.bbrc.2020.05.037.

566. Shunda Wang, Jinshou Yang, Cheng Ding, Junjie Li, Lei You, Menghua Dai, Yupei Zhao

Glutathione S-Transferase Mu-3 Predicts a Better Prognosis and Inhibits Malignant Behavior and Glycolysis in Pancreatic Cancer

Front Oncol. 2020 Aug 28;10:1539. doi: 10.3389/fonc.2020.01539. (IF 4.848)

567. Qianqian Yu, Xiaojing Tian, Lele Shao, Xingmin Li, Ruitong Dai

Mitochondria changes and metabolome differences of bovine longissimus lumborum and psoas major during 24 h postmortem

Meat Sci. 2020 Aug;166:108112. doi: 10.1016/j.meatsci.2020.108112. (IF 3.644)

568. Yufeng Liu, Zhimin Zhang, Qing Li, Liang Zhang, Yi Cheng, Zhaoyang Zhong

Mitochondrial APE1 promotes cisplatin resistance by downregulating ROS in osteosarcoma

Oncol Rep. 2020 Aug;44(2):499-508. doi: 10.3892/or.2020.7633. (IF 3.417)

569. Xiaohui Zhou, Jing Liu, Siyi Yang, Yanguang Su, Zhipeng Meng, Yuqin Hu

K etamine ameliorates hypoxia-induced endothelial injury in human umbilical vein endothelial cells

Clinics (Sao Paulo). 2020 Sep 11;75:e1865. doi: 10.6061/clinics/2020/e1865.

570. Ke Zheng, Hongyan Liu, Xinxin Liu, Libin Jiang, Linlin Li, Xianggen Wu, Nannan Guo, Caifeng Ding, Mingdong Huang

Photo-triggered release of doxorubicin from liposomes formulated by amphiphilic phthalocyanines for combination therapy to enhance antitumor efficacy

J Mater Chem B. 2020 Sep 21;8(35):8022-8036. doi: 10.1039/d0tb01093f. (IF 5.344)

571. Fenshuang Zheng, Tao Liu, Junbo Zhu, Yuan Xie, Lianjun Wu, Zhaoheng Lin

FoxF1 protects rats from paraquat-evoked lung injury following HDAC2 inhibition via the microRNA-342/KLF5/IκB/NF-κB p65 axis

Exp Cell Res. 2020 Oct 15;395(2):112208. doi: 10.1016/j.yexcr.2020.112208. (IF 3.383)

572. Jiating Lin, Rongyao Xu, Xiang Shen, Hongbing Jiang, Shuhu Du

Metformin promotes the osseointegration of titanium implants under osteoporotic conditions by regulating BMSCs autophagy, and osteogenic differentiation

Biochem Biophys Res Commun. 2020 Oct 15;531(2):228-235. doi: 10.1016/j.bbrc.2020.06.146.

573. Yang Sun, Xianfang Rong, Dan Li, Yongxiang Jiang, Yi Lu, Yinghong Ji

Down-regulation of CRTAC1 attenuates UVB-induced pyroptosis in HLECs through inhibiting ROS production

Biochem Biophys Res Commun. 2020 Oct 29;532(1):159-165. doi: 10.1016/j.bbrc.2020.07.028.

574. Jinmeng Yang, Daqian Dong, Guofan Peng, Qingfang Sun, Chenhao Yang, Yao Gao, Hong Ji, Wuzi Dong

Melatonin regulates ATP content and fertilising capacity of Onychostoma macrolepis spermatozoa by inhibiting ROS accumulation during semen storage in vitro

Reprod Fertil Dev. 2020 Oct;32(14):1212-1222. doi: 10.1071/RD20153.

575. Xue Li, Xin Li

Obesity Promotes Experimental Colitis by Increasing Oxidative Stress and Mitochondrial Dysfunction in the Colon

Inflammation. 2020 Oct;43(5):1884-1892. doi: 10.1007/s10753-020-01261-6. (IF 3.212)

576. Yingying Hong, Yang Sun, Xianfang Rong, Dan Li, Yi Lu, Yinghong Ji

Exosomes from adipose-derived stem cells attenuate UVB-induced apoptosis, ROS, and the Ca 2+ level in HLEC cells

Exp Cell Res. 2020 Nov 15;396(2):112321. doi: 10.1016/j.yexcr.2020.112321. (IF 3.383)

577. Kai Li, Yang Xue, Lan Zhang, Yong Han

β-FeOOH/Fe-TiO 2 heterojunctions on Ti for bacteria inactivation under light irradiation and biosealing

Biomater Sci. 2020 Nov 7;8(21):6004-6016. doi: 10.1039/d0bm01290d.

578. Qun Zhao, Jing Zhong, Yun Bi, Yongqiang Liu, Yingxiang Liu, Jian Guo, Longrui Pan, Yan Tan, Xianjun Yu

Gambogenic acid induces Noxa-mediated apoptosis in colorectal cancer through ROS-dependent activation of IRE1α/JNK

Phytomedicine. 2020 Nov;78:153306. doi: 10.1016/j.phymed.2020.153306. (IF 4.268)

579. Maoxing Fei, Li Zhang, Handong Wang, Yihao Zhu, Wenhao Niu, Ting Tang, Yanling Han

Inhibition of Cathepsin S Induces Mitochondrial Apoptosis in Glioblastoma Cell Lines Through Mitochondrial Stress and Autophagosome Accumulation

Front Oncol. 2020 Dec 23;10:516746. doi: 10.3389/fonc.2020.516746. (IF 4.848)

580. Qian Feng, Yu Chen, Lin Wang, Mengmei Li, Jie Teng, Yuming Chen, Zhongzhen Cai, Glen Rein, B Qing Tang, Xuemei Bai

Effect of information fields from written texts on cell growth and mitochondrial functions in-vitro: An exploratory study

Explore (NY). 2020 Dec 5;S1550-8307(20)30409-2. doi: 10.1016/j.explore.2020.12.001.

581. Xuefeng Qu, Zhouyi Zhang, Wenli Hu, Minhan Lou, Bingzhong Zhai, Song Mei, Zhihang Hu, Lijing Zhang, Dongying Liu, Zhen Liu, Jianguo Chen, Yin Wang

Attenuation of the Na/K‑ATPase/Src/ROS amplification signaling pathway by astaxanthin ameliorates myocardial cell oxidative stress injury

Mol Med Rep. 2020 Dec;22(6):5125-5134. doi: 10.3892/mmr.2020.11613. (IF 2.1)

582. Lijia Pan, Litong Nie, Sheng Yao, Aiwei Bi, Yang Ye, Yeming Wu, Zhen Tan, Zhixiang Wu

Bufalin exerts antitumor effects in neuroblastoma via the induction of reactive oxygen species‑mediated apoptosis by targeting the electron transport chain

Int J Mol Med. 2020 Dec;46(6):2137-2149. doi: 10.3892/ijmm.2020.4745. (IF 3.098)

583. Jiandi Wu, Jingjing Liang, Meijun Li, Mingzhuo Lin, Linlin Mai, Xiaohui Huang, Jianqiu Liang, Yunzhao Hu, Yuli Huang

Modulation of miRNAs by vitamin C in H2O2‑exposed human umbilical vein endothelial cells

Int J Mol Med. 2020 Dec;46(6):2150-2160. doi: 10.3892/ijmm.2020.4753. (IF 3.098)

584. Xiaoqiu Zhu, Yiyi Yao, Mingyan Guo, Jin Li, Pengfeng Yang, Hui Xu, Daowei Lin

Sevoflurane increases intracellular calcium to induce mitochondrial injury and neuroapoptosis

Toxicol Lett. 2021 Jan 1;336:11-20. doi: 10.1016/j.toxlet.2020.11.002. (IF 3.569)

585. Rui Li, Beini Wang, Chengbiao Wu, Duohui Li, Yanqing Wu, Libing Ye, Luxia Ye, Xiongjian Chen, Peifeng Li, Yuan Yuan, Hongyu Zhang, Ling Xie, Xiaokun Li, Jian Xiao, Jian Wang

Acidic fibroblast growth factor attenuates type 2 diabetes-induced demyelination via suppressing oxidative stress damage

Cell Death Dis. 2021 Jan 21;12(1):107. doi: 10.1038/s41419-021-03407-2. (IF 6.304)

586. Hui Li, Linlin Liu, Zhiwen Cao, Wen Li, Rui Liu, Youwen Chen, Chenxi Li, Yurong Song, Guangzhi Liu, Jinghong Hu, Zhenli Liu, Cheng Lu, Yuanyan Liu

Naringenin ameliorates homocysteine induced endothelial damage via the AMPKα/Sirt1 pathway

J Adv Res. 2021 Jan 23;34:137-147. doi: 10.1016/j.jare.2021.01.009. (IF 6.992)

587. Gang Liu, Qingbai Liu, Bin Yan, Ziqiang Zhu, Yaozeng Xu

USP7 Inhibition Alleviates H2O2-Induced Injury in Chondrocytes via Inhibiting NOX4/NLRP3 Pathway

Front Pharmacol. 2021 Jan 29;11:617270. doi: 10.3389/fphar.2020.617270. (IF 4.225)

588. Huanliang Liu, Wenqing Lai, Xiaohua Liu, Honglian Yang, Yanjun Fang, Lei Tian, Kang Li, Huipeng Nie, Wei Zhang, Yue Shi, Liping Bian, Susu Ding, Jun Yan, Bencheng Lin, Zhuge Xi

Exposure to copper oxide nanoparticles triggers oxidative stress and endoplasmic reticulum (ER)-stress induced toxicology and apoptosis in male rat liver and BRL-3A cell

J Hazard Mater. 2021 Jan 5;401:123349. doi: 10.1016/j.jhazmat.2020.123349. (IF 9.038)

589. Chuanchuan Shi, Yuqian Zhao, Qi Li, Jianguo Li

lncRNA SNHG14 Plays a Role in Sepsis-Induced Acute Kidney Injury by Regulating miR-93

Mediators Inflamm. 2021 Jan 6;2021:5318369. doi: 10.1155/2021/5318369.

590. Meng Xia, Xuena Li, Yao Diao, Bulin Du, Yaming Li

Targeted inhibition of glutamine metabolism enhances the antitumor effect of selumetinib in KRAS-mutant NSCLC

Transl Oncol. 2021 Jan;14(1):100920. doi: 10.1016/j.tranon.2020.100920. (IF 3.558)

591. Xiaolin Shi, Wei Zhang, Cheng Gu, Huangge Ren, Chen Wang, Narui Yin, Zhongmin Wang, Jiahua Yu, Fenju Liu, Haowen Zhang

NAD+ depletion radiosensitizes 2-DG-treated glioma cells by abolishing metabolic adaptation

Free Radic Biol Med. 2021 Jan;162:514-522. doi: 10.1016/j.freeradbiomed.2020.11.007.

592. Doudou Jing, Wei Wu, Xiangyu Deng, Yizhong Peng, Wenbo Yang, Donghua Huang, Zengwu Shao, Dong Zheng

FoxO1a mediated cadmium-induced annulus fibrosus cells apoptosis contributes to intervertebral disc degeneration in smoking

J Cell Physiol. 2021 Jan;236(1):677-687. doi: 10.1002/jcp.29895. (IF 5.546)

593. Keji Zhang, Yuan Gao, Yuxiao Deng, Xiao Zhou, Changqing Zhu, Zhengyu He, Dan Lv

Studies on the effects of bone marrow stem cells on mitochondrial function and the alleviation of ARDS

Mol Cell Biochem. 2021 Jan;476(1):93-107. doi: 10.1007/s11010-020-03888-3. (IF 2.795)

594. Fan Yang, Yuanshuai Zhou, Huidan Yu, Jiao Yang, Cheng Zhu, Nafees Ahmad, Xingjun Meng, Rongchuan Zhao, Jie Zhuang, Minxuan Sun

Combination of metformin and cold atmospheric plasma induces glioma cell death to associate with c-Fos

Neoplasma. 2021 Jan;68(1):126-134. doi: 10.4149/neo_2020_200325N307. (IF 1.721)

595. Qun Zhao, Yun Bi, Jian Guo, Yingxiang Liu, Jing Zhong, Yongqiang Liu, Longrui Pan, Yang Guo, Yan Tan, Xianjun Yu

Effect of pristimerin on apoptosis through activation of ROS/ endoplasmic reticulum (ER) stress-mediated noxa in colorectal cancer

Phytomedicine. 2021 Jan;80:153399. doi: 10.1016/j.phymed.2020.153399. (IF 4.268)

596. Guiling Li, Yuanyuan Li, Baoping Xiao, Dongyue Cui, Yanqi Lin, Jun Zeng, Jian Li, Min-Jie Cao, Jingwen Liu

Antioxidant Activity of Docosahexaenoic Acid (DHA) and Its Regulatory Roles in Mitochondria

J Agric Food Chem. 2021 Feb 10;69(5):1647-1655. doi: 10.1021/acs.jafc.0c07751.

597. Moran Huang, Kai Ye, Tu Hu, Kexin Liu, Mengzhen You, Lei Wang, Hui Qin

Silver Nanoparticles Attenuate the Antimicrobial Activity of the Innate Immune System by Inhibiting Neutrophil-Mediated Phagocytosis and Reactive Oxygen Species Production

Int J Nanomedicine. 2021 Feb 18;16:1345-1360. doi: 10.2147/IJN.S292482.

598. Biao Chen, Xiaoqi Dong, Xiyuan Dong, Quan Wang, Meng Wu, Jun Wu, Xiaoding Lou, Fan Xia, Wenwen Wang, Jun Dai, Shixuan Wang

Integration of Dual Targeting and Dual Therapeutic Modules Endows Self-Assembled Nanoparticles with Anti-Tumor Growth and Metastasis Functions

Int J Nanomedicine. 2021 Feb 18;16:1361-1376. doi: 10.2147/IJN.S291285.

599. Junxing Yang, Jianliang Liu, Ping Wang, Juanjuan Sun, Xiaohui Lv, Yumei Diao

Toxic effect of titanium dioxide nanoparticles on corneas in vitro and in vivo

Aging (Albany NY). 2021 Feb 1;13(4):5020-5033. doi: 10.18632/aging.202412.

600. Zhiyin Wang, Bin Cai, Chenrui Cao, Haining Lv, Yimin Dai, Mingming Zheng, Guangfeng Zhao, Yanfang Peng, Wenjing Gou, Jingmei Wang, Dan Liu, Yali Hu

Downregulation of CD151 induces oxidative stress and apoptosis in trophoblast cells via inhibiting ERK/Nrf2 signaling pathway in preeclampsia

Free Radic Biol Med. 2021 Feb 20;164:249-257. doi: 10.1016/j.freeradbiomed.2020.12.441.

601. Changkuo Zhou, Ganyu Wang, Weiqiang Jing, Xuejie Tan, Hu Guo

Anticancer Properties and Mechanisms of Singly-Protonated Dehydronorcantharidin Silver Coordination Polymer in a Bladder Cancer Model

Front Pharmacol. 2021 Feb 23;12:618668. doi: 10.3389/fphar.2021.618668. (IF 4.225)

602. Yuqi Lai, Qinxiang Tan, Shu Xv, Sha Huang, Yuhua Wang, Yunjia Li, Ting Zeng, Chan Mo, Yuyao Chen, Shaohui Huang, Chuying Zhou, Lei Gao, Zhiping Lv

Ginsenoside Rb1 Alleviates Alcohol-Induced Liver Injury by Inhibiting Steatosis, Oxidative Stress, and Inflammation

Front Pharmacol. 2021 Feb 26;12:616409. doi: 10.3389/fphar.2021.616409. (IF 4.225)

603. Zhuochao Liu, Hongyi Wang, Chuanzhen Hu, Chuanlong Wu, Jun Wang, Fangqiong Hu, Yucheng Fu, Junxiang Wen, Weibin Zhang

Targeting autophagy enhances atezolizumab-induced mitochondria-related apoptosis in osteosarcoma

Cell Death Dis. 2021 Feb 8;12(2):164. doi: 10.1038/s41419-021-03449-6. (IF 6.304)

604. Zhiping Li, Hui Bi, Hongbo Jiang, Jingjing Song, Qingfan Meng, Yizhi Zhang, Xiaofang Fei

Neuroprotective effect of emodin against Alzheimer's disease via Nrf2 signaling in U251 cells and APP/PS1 mice

Mol Med Rep. 2021 Feb;23(2):108. doi: 10.3892/mmr.2020.11747. (IF 2.1)

605. Lina Wu, Qingzhu Wang, Feng Guo, Xiaojun Ma, Jiao Wang, Yanyan Zhao, Yushan Yan, Guijun Qin

Involvement of miR-27a-3p in diabetic nephropathy via affecting renal fibrosis, mitochondrial dysfunction, and endoplasmic reticulum stress

J Cell Physiol. 2021 Feb;236(2):1454-1468. doi: 10.1002/jcp.29951. (IF 5.546)

606. Yiming Zhu, Chihao Zhang, Mingzhe Huang, Jiayun Lin, Xiao Fan, Tao Ni

TRIM26 Induces Ferroptosis to Inhibit Hepatic Stellate Cell Activation and Mitigate Liver Fibrosis Through Mediating SLC7A11 Ubiquitination

Front Cell Dev Biol. 2021 Mar 25;9:644901. doi: 10.3389/fcell.2021.644901. (IF 5.201)

607. Mengmeng Yang, Yixin Cui, Jia Song, Chen Cui, Lingshu Wang, Kai Liang, Chuan Wang, Sha Sha, Qin He, Huiqing Hu, Xinghong Guo, Nan Zang, Lei Sun, Li Chen

Mesenchymal stem cell-conditioned medium improved mitochondrial function and alleviated inflammation and apoptosis in non-alcoholic fatty liver disease by regulating SIRT1

Biochem Biophys Res Commun. 2021 Mar 26;546:74-82. doi: 10.1016/j.bbrc.2021.01.098.

608. Tiantian Lou, Jin Ma, Yanzheng Xie, Gengzhen Yao, Ye Fan, Shiyu Ma, Xu Zou

Nuanxin capsule enhances cardiac function by inhibiting oxidative stress-induced mitochondrial dependent apoptosis through AMPK/JNK signaling pathway

Biomed Pharmacother. 2021 Mar;135:111188. doi: 10.1016/j.biopha.2020.111188. (IF 4.545)

609. Bao-You Fan, Yi-Lin Pang, Wen-Xiang Li, Chen-Xi Zhao, Yan Zhang, Xu Wang, Guang-Zhi Ning, Xiao-Hong Kong, Chang Liu, Xue Yao, Shi-Qing Feng

Liproxstatin-1 is an effective inhibitor of oligodendrocyte ferroptosis induced by inhibition of glutathione peroxidase 4

Neural Regen Res. 2021 Mar;16(3):561-566. doi: 10.4103/1673-5374.293157. (IF 3.171)

610. Jin Hou, Ling Zhao, Huaqiao Tang, Xiaoli He, Gang Ye, Fei Shi, Min Kang, Helin Chen, Yinglun Li

Silver Nanoparticles Induced Oxidative Stress and Mitochondrial Injuries Mediated Autophagy in HC11 Cells Through Akt/AMPK/mTOR Pathway

Biol Trace Elem Res. 2021 Mar;199(3):1062-1073. doi: 10.1007/s12011-020-02212-w. (IF 2.639)

611. Hao Yan, Fei Xu, Jun Xu, Ming-Ai Song, Kai Wang, Lulu Wang

Activation of Akt-dependent Nrf2/ARE pathway by restoration of Brg-1 remits high glucose-induced oxidative stress and ECM accumulation in podocytes

J Biochem Mol Toxicol. 2021 Mar;35(3):e22672. doi: 10.1002/jbt.22672.

612. Yuan He, Xinlin Lu, Tao Chen, Yu Yang, Jing Zheng, Can Chen, Yuanqi Zhang, Wei Lei

Resveratrol protects against myocardial ischemic injury via the inhibition of NF‑κB‑dependent inflammation and the enhancement of antioxidant defenses

Int J Mol Med. 2021 Mar;47(3):29. doi: 10.3892/ijmm.2021.4862. (IF 3.098)

613. Bingbing Zhao, Siwei Li, Zuoming Guo, Zhe Chen, Xinying Zhang, Changqing Xu, Junting Chen, Can Wei

Dopamine receptor D2 inhibition alleviates diabetic hepatic stellate cells fibrosis by regulating the TGF-β1/Smads and NFκB pathways

Clin Exp Pharmacol Physiol. 2021 Mar;48(3):370-380. doi: 10.1111/1440-1681.13437.

614. Ke Zheng, Xinxin Liu, Hongyan Liu, Dianquan Dong, Linlin Li, Libin Jiang, Mingdong Huang, Caifeng Ding

Novel pH-Triggered Doxorubicin-Releasing Nanoparticles Self-Assembled by Functionalized β-Cyclodextrin and Amphiphilic Phthalocyanine for Anticancer Therapy

ACS Appl Mater Interfaces. 2021 Mar 10;13(9):10674-10688. doi: 10.1021/acsami.0c19027.

615. Fengjiao Wang, Lai Wang, Chao Qu, Lianyu Chen, Yawen Geng, Chienshan Cheng, Shulin Yu, Dan Wang, Lina Yang, Zhiqiang Meng, Zhen Chen

Kaempferol induces ROS-dependent apoptosis in pancreatic cancer cells via TGM2-mediated Akt/mTOR signaling

BMC Cancer. 2021 Apr 12;21(1):396. doi: 10.1186/s12885-021-08158-z. (IF 3.15)

616. Xiao Xiao, Zhiwen Tan, Min Jia, Xiaoli Zhou, Kemei Wu, Yanbing Ding, Wenjing Li

Long Noncoding RNA SNHG1 Knockdown Ameliorates Apoptosis, Oxidative Stress and Inflammation in Models of Parkinson's Disease by Inhibiting the miR-125b-5p/MAPK1 Axis

Neuropsychiatr Dis Treat. 2021 Apr 22;17:1153-1163. doi: 10.2147/NDT.S286778.

617. Haiyingjie Lin, Xiaoting Chen, Chengyong Zhang, Tingting Yang, Zhendong Deng, Yuwei Song, Lanlan Huang, Fuxiang Li, Qingchu Li, Shaoqiang Lin, Dadi Jin

EF24 induces ferroptosis in osteosarcoma cells through HMOX1

Biomed Pharmacother. 2021 Apr;136:111202. doi: 10.1016/j.biopha.2020.111202. (IF 4.545)

618. Qiang Zheng, Zhenning Liu, Haitao Shen, Xiao Hu, Min Zhao

Protective effect of toll-interacting protein overexpression against paraquat-induced lung injury in mice and A549 cells through inhibiting oxidative stress, inflammation, and NF-κB signaling pathway

Respir Physiol Neurobiol. 2021 Apr;286:103600. doi: 10.1016/j.resp.2020.103600.

619. Li Zhang, Mengwen Feng, Xuejun Wang, Hao Zhang, Jingjing Ding, Zijie Cheng, Lingmei Qian

Peptide Szeto‑Schiller 31 ameliorates doxorubicin‑induced cardiotoxicity by inhibiting the activation of the p38 MAPK signaling pathway

Int J Mol Med. 2021 Apr;47(4):63. doi: 10.3892/ijmm.2021.4896. (IF 3.098)

620. Yin Yuan, Shuo Ni, Aoxiang Zhuge, Bo Li, Lanjuan Li

Iron Regulates the Warburg Effect and Ferroptosis in Colorectal Cancer

Front Oncol. 2021 May 18;11:614778. doi: 10.3389/fonc.2021.614778. (IF 4.848)

621. Qiuhong Xiong, Xin Li, Wenjing Li, Guangxin Chen, Han Xiao, Ping Li, Changxin Wu

WDR45 Mutation Impairs the Autophagic Degradation of Transferrin Receptor and Promotes Ferroptosis

Front Mol Biosci. 2021 May 3;8:645831. doi: 10.3389/fmolb.2021.645831. (IF 4.188)

622. Yong Xu, Shi Wang, Longshun Yang, Yuhang Dong, Yafang Zhang, Guoqing Yan, Rupei Tang

pH-sensitive micelles self-assembled from star-shaped TPGS copolymers with ortho ester linkages for enhanced MDR reversal and chemotherapy

Asian J Pharm Sci. 2021 May;16(3):363-373. doi: 10.1016/j.ajps.2021.01.002. (IF 3.968)

623. He Li, Yin Luo, Peng Liu, Pei Liu, Weilong Hua, Yongxin Zhang, Lei Zhang, Zifu Li, Pengfei Xing, Yongwei Zhang, Bo Hong, Pengfei Yang, Jianmin Liu

Exosomes containing miR-451a is involved in the protective effect of cerebral ischemic preconditioning against cerebral ischemia and reperfusion injury

CNS Neurosci Ther. 2021 May;27(5):564-576. doi: 10.1111/cns.13612. (IF 4.074)

624. Jiaping Zheng, Yunzhen Xie, Lingjia Ren, Liqin Qi, Li Wu, Xiaodong Pan, Jianxing Zhou, Zhou Chen, Libin Liu

GLP-1 improves the supportive ability of astrocytes to neurons by promoting aerobic glycolysis in Alzheimer's disease

Mol Metab. 2021 May;47:101180. doi: 10.1016/j.molmet.2021.101180. (IF 6.448)

625. Liuyan Wu, Zhenlong Kang, Na Qiao, Congcong Wang, Zhaoxin Tang

Cu-induced mitochondrial dysfunction is mediated by abnormal mitochondrial fission through oxidative stress in primary chicken embryo hepatocytes

J Trace Elem Med Biol. 2021 May;65:126721. doi: 10.1016/j.jtemb.2021.126721.

626. Qiang Zheng, Yuan Zhang, Zheng Zhao, Haitao Shen, Hongyu Zhao, Min Zhao

Isorhynchophylline ameliorates paraquat-induced acute kidney injury by attenuating oxidative stress and mitochondrial damage via regulating toll-interacting expression

Toxicol Appl Pharmacol. 2021 Jun 1;420:115521. doi: 10.1016/j.taap.2021.115521.

627. Hai-Ping Xu, Xiao-Ying Ma, Chen Yang

Circular RNA TLK1 Promotes Sepsis-Associated Acute Kidney Injury by Regulating Inflammation and Oxidative Stress Through miR-106a-5p/HMGB1 Axis

Front Mol Biosci. 2021 Jun 25;8:660269. doi: 10.3389/fmolb.2021.660269. (IF 4.188)

628. Jing Yang, Lin Wu, Shanshou Liu, Xiaomin Hu, Qianmei Wang, Liying Fang

Long non-coding RNA NEAT1 promotes lipopolysaccharide-induced injury in human tubule epithelial cells by regulating miR-93-5p/TXNIP axis

Med Microbiol Immunol. 2021 Jun;210(2-3):121-132. doi: 10.1007/s00430-021-00705-6.

629. Yong Xu, Xiang Li, Hailun Li, Lili Zhong, Yongtao Lin, Juan Xie, Donghui Zheng

Circ_0023404 sponges miR-136 to induce HK-2 cells injury triggered by hypoxia/reoxygenation via up-regulating IL-6R

J Cell Mol Med. 2021 Jun;25(11):4912-4921. doi: 10.1111/jcmm.15986. (IF 4.486)

630. Xingzhi Jing, Ting Du, Tao Li, Xiaoxia Yang, Guodong Wang, Xiaoyang Liu, Zhensong Jiang, Xingang Cui

The detrimental effect of iron on OA chondrocytes: Importance of pro-inflammatory cytokines induced iron influx and oxidative stress

J Cell Mol Med. 2021 Jun;25(12):5671-5680. doi: 10.1111/jcmm.16581. (IF 4.486)

631. Dongmei Jiang, Yilong Jiang, Shiyun Long, Ziyu Chen, Yanling Li, Guilin Mo, Lin Bai, Xiaoxia Hao, Yanhong Yan, Liang Li, Chunchun Han, Shenqiang Hu, Hua Zhao, Bo Kang

Spermidine at supraphysiological doses induces oxidative stress and granulosa cell apoptosis in mouse ovaries

Theriogenology. 2021 Jul 1;168:25-32. doi: 10.1016/j.theriogenology.2021.03.026. (IF 2.094)

632. Zhengwang Sun, Zirui He, Rujiao Liu, Zhe Zhang

Cation Lipid-Assisted PEG6-PLGA Polymer Nanoparticles Encapsulated Knocking Down Long ncRNAs Reverse Non-Coding RNA of Xist Through the Support Vector Machine Model to Regulate the Molecular Mechanism

J Biomed Nanotechnol. 2021 Jul 1;17(7):1305-1319. doi: 10.1166/jbn.2021.3107.

633. Duanfeng Jiang, Kaixuan Zhang, Yinghong Zhu, Yan Zhu, Lang Zou, Jian Hu, Yajuan Cui, Wen Zhou, Fangping Chen, Yanjuan He

Chidamide-Induced Accumulation of Reactive Oxygen Species Increases Lenalidomide Sensitivity Against Multiple Myeloma Cells

Onco Targets Ther. 2021 Jul 6;14:4061-4075. doi: 10.2147/OTT.S312249.

634. Junfang Liang, Liyang Lian, Xiaoli Wang, Liang Li

Thymoquinone, extract from Nigella sativa seeds, protects human skin keratinocytes against UVA-irradiated oxidative stress, inflammation and mitochondrial dysfunction

Mol Immunol. 2021 Jul;135:21-27. doi: 10.1016/j.molimm.2021.03.015. (IF 3.641)

635. Wei Wu, Doudou Jing, Xin Huang, Wenbo Yang, Zengwu Shao

Drp1-mediated mitochondrial fission is involved in oxidized low-density lipoprotein-induced AF cella poptosis

J Orthop Res. 2021 Jul;39(7):1496-1504. doi: 10.1002/jor.24828. (IF 2.728)

636. Xin Wang, Jia-Ying Yu, Yan Sun, Heng Wang, Hu Shan, Shubai Wang

Baicalin protects LPS-induced blood-brain barrier damage and activates Nrf2-mediated antioxidant stress pathway

Int Immunopharmacol. 2021 Jul;96:107725. doi: 10.1016/j.intimp.2021.107725. (IF 3.943)

637. Jing Zhen, Kailin Jiao, Keke Yang, Maoxuan Wu, Qian Zhou, Bingmo Yang, Wei Xiao, Chunyan Hu, Ming Zhou, Zhong Li

The 14-3-3η/GSK-3β/β-catenin complex regulates EndMT induced by 27-hydroxycholesterol in HUVECs and promotes the migration of breast cancer cells

Cell Biol Toxicol. 2021 Aug;37(4):515-529. doi: 10.1007/s10565-020-09564-y. (IF 6.284)

638. Siwen Li, Yang Cao, Qiangwen Pan, Yewei Xiao, Yanling Wang, Xiali Wang, Xinlian Li, Qiuyue Li, Xiaoqing Tang, Bing Ran

Neonicotinoid insecticides triggers mitochondrial bioenergetic dysfunction via manipulating ROS-calcium influx pathway in the liver

Ecotoxicol Environ Saf. 2021 Aug 20;224:112690. doi: 10.1016/j.ecoenv.2021.112690.

639. Shuge Sun, Wei Shi, Yu Tang, Yu Han, Xueying Du, Weishang Zhou, Weixia Zhang, Changsen Sun, Guangxu Liu

The toxic impacts of microplastics (MPs) and polycyclic aromatic hydrocarbons (PAHs) on haematic parameters in a marine bivalve species and their potential mechanisms of action

Sci Total Environ. 2021 Aug 20;783:147003. doi: 10.1016/j.scitotenv.2021.147003. (IF 6.551)

640. Yongpeng Zou, Xing Luo, Yi Feng, Shaohong Fang, Jiangtian Tian, Bo Yu, Ji Li

Luteolin prevents THP-1 macrophage pyroptosis by suppressing ROS production via Nrf2 activation

Chem Biol Interact. 2021 Aug 25;345:109573. doi: 10.1016/j.cbi.2021.109573.

641. Yang Zhao, Sainan Liu, Zhili Sheng, Xue Li, Yanan Chang, Weichang Dai, Sui Kiat Chang, Junmei Liu, Yuchun Yang

Effect of pinolenic acid on oxidative stress injury in HepG2 cells induced by H2O2

Food Sci Nutr. 2021 Aug 25;9(10):5689-5697. doi: 10.1002/fsn3.2534. (IF 1.797)

642. Xiangyu Wu, Zitong Wang, Yanan Jiang, Hao Zhou, Ang Li, Yaxing Wei, Zhuo Bao, Donghao Wang, Jimin Zhao, Xinhuan Chen, Yaping Guo, Zigang Dong, Kangdong Liu

Tegas erod Maleate Inhibits Esophageal Squamous Cell Carcinoma Proliferation by Suppressing the Peroxisome Pathway

Front Oncol. 2021 Aug 4;11:683241. doi: 10.3389/fonc.2021.683241. (IF 4.848)

643. Rui Kong, Nan Wang, Wei Han, Wen Bao, Jie Lu

IFNγ-mediated repression of system xc- drives vulnerability to induced ferroptosis in hepatocellular carcinoma cells

J Leukoc Biol. 2021 Aug;110(2):301-314. doi: 10.1002/JLB.3MA1220-815RRR.

644. J Bai, P Jia, Y Zhang, K Wang, G Wu

Paraoxonase 2 protects against oxygen-glucose deprivation/reoxygenation-induced neuronal injury by enhancing Nrf2 activation via GSK-3β modulation

Hum Exp Toxicol. 2021 Aug;40(8):1342-1354. doi: 10.1177/0960327121996032. (IF 2.067)

645. Meimei Wang, Yan Li, Yanxia Gao, Qiufeng Li, Yufeng Cao, Yizhao Shen, Panliang Chen, Jinling Yan, Jianguo Li

Vitamin E regulates bovine granulosa cell apoptosis via NRF2-mediated defence mechanism by activating PI3K/AKT and ERK1/2 signalling pathways

Reprod Domest Anim. 2021 Aug;56(8):1066-1084. doi: 10.1111/rda.13950. (IF 1.641)

646. Yanfeng Ding, Zhimin Li, Wenwen Hu, Xianjing Feng, Ying Chen, Guohua Yan, Yonglin Wang, Bo Zhu, Wei Yao, Li Zheng, Maolin He, Ming Gao, Jinmin Zhao

Carbazate-modified cross-linked dextran microparticles suppress the progression of osteoarthritis by ROS scavenging

Biomater Sci. 2021 Sep 14;9(18):6236-6250. doi: 10.1039/d1bm00743b.

647. Gecai Chen, Meixiang Wang, Zhongbao Ruan, Li Zhu, Chengchun Tang

Mesenchymal stem cell-derived exosomal miR-143-3p suppresses myocardial ischemia-reperfusion injury by regulating autophagy

Life Sci. 2021 Sep 1;280:119742. doi: 10.1016/j.lfs.2021.119742. (IF 3.647)

648. Yong-Li Zhang, Gui-Lin Chen, Ye Liu, Xiao-Cui Zhuang, Ming-Quan Guo

Stimulation of ROS Generation by Extract of Warburgia ugandensis Leading to G0/G1 Cell Cycle Arrest and Antiproliferation in A549 Cells

Antioxidants (Basel). 2021 Sep 30;10(10):1559. doi: 10.3390/antiox10101559.

649. Hanyu Shi, Jie Liu, Haiqing Gao

Benzo(α)pyrene induces oxidative stress and inflammation in human vascular endothelial cells through AhR and NF-κB pathways

Microvasc Res. 2021 Sep;137:104179. doi: 10.1016/j.mvr.2021.104179. (IF 2.73)

650. Chunju Fang, Fei Mo, Li Liu, Jing Du, Min Luo, Ke Men, Feifei Na, Wei Wang, Hanshuo Yang, Xiawei Wei

Oxidized mitochondrial DNA sensing by STING signaling promotes the antitumor effect of an irradiated immunogenic cancer cell vaccine

Cell Mol Immunol. 2021 Sep;18(9):2211-2223. doi: 10.1038/s41423-020-0456-1. (IF 8.484)

651. Huihua Li, Yujun Shen, Hui Xiao, Wei Sun

Resveratrol attenuates rotenone-induced inflammation and oxidative stress via STAT1 and Nrf2/Keap1/SLC7A11 pathway in a microglia cell line

Pathol Res Pract. 2021 Sep;225:153576. doi: 10.1016/j.prp.2021.153576. (IF 2.05)

652. Chenyang Zhang, Xin Wang, Xinghua Dong, Linqiang Mei, Xiaochen Wu, Zhanjun Gu, Yuliang Zhao

X-ray-facilitated redox cycling of nanozyme possessing peroxidase-mimicking activity for reactive oxygen species-enhanced cancer therapy

Biomaterials. 2021 Sep;276:121023. doi: 10.1016/j.biomaterials.2021.121023. (IF 10.317)

653. Hao Zhang, Shengduo Xu, Jishen Zhang, Zifeng Wang, Dingxin Liu, Li Guo, Cheng Cheng, Yilong Cheng, Dehui Xu, Michael G Kong, Mingzhe Rong, Paul K Chu

Plasma-activated thermosensitive biogel as an exogenous ROS carrier for post-surgical treatment of cancer

Biomaterials. 2021 Sep;276:121057. doi: 10.1016/j.biomaterials.2021.121057. (IF 10.317)

654. Hongsong Li, Rong Li, Lijun Wang, Dingying Liao, Wenyi Zhang, Jianming Wang

Proanthocyanidins attenuate the high glucose-induced damage of retinal pigment epithelial cells by attenuating oxidative stress and inhibiting activation of the NLRP3 inflammasome

J Biochem Mol Toxicol. 2021 Sep;35(9):e22845. doi: 10.1002/jbt.22845.

655. Lidong Zhao, Miao Xiong, Yang Liu

Baicalin enhances the proliferation and invasion of trophoblasts and suppresses vascular endothelial damage by modulating long non-coding RNA NEAT1/miRNA-205-5p in hypertensive disorder complicating p

J Obstet Gynaecol Res. 2021 Sep;47(9):3060-3070. doi: 10.1111/jog.14789.

656. Yu He, Yuchuan Shi, Yang Yang, Huanhuan Huang, Yifan Feng, Yunmeng Wang, Lei Zhan, Bing Wei

Chrysin induces autophagy through the inactivation of the ROS‑mediated Akt/mTOR signaling pathway in endometrial cancer

Int J Mol Med. 2021 Sep;48(3):172. doi: 10.3892/ijmm.2021.5005. (IF 3.098)

657. Jiehuan Xu, Lingwei Sun, Caifeng Wu, Shushan Zhang, Shiqiang Ju, Rong Rui, Defu Zhang, Jianjun Dai

Involvement of PINK1/Parkin-mediated mitophagy in mitochondrial functional disruption under oxidative stress in vitrified porcine oocytes

Theriogenology. 2021 Oct 15;174:160-168. doi: 10.1016/j.theriogenology.2021.08.028. (IF 2.094)

658. Yi Luo, Xu Gao, Luetao Zou, Miao Lei, Junming Feng, Zhenming Hu

Bavachin Induces Ferroptosis through the STAT3/P53/SLC7A11 Axis in Osteosarcoma Cells

Oxid Med Cell Longev. 2021 Oct 18;2021:1783485. doi: 10.1155/2021/1783485. (IF 5.076)

659. Jingyu Ren, Yuchun Hao, Zhanpeng Liu, Shubin Li, Chunyu Wang, Biao Wang, Yongbin Liu, Gang Liu, Yanfeng Dai

Effect of exogenous glutathione supplementation on the in vitro developmental competence of ovine oocytes

Theriogenology. 2021 Oct 1;173:144-155. doi: 10.1016/j.theriogenology.2021.07.025. (IF 2.094)

660. Yongfeng Liu, Cheng-E Tu, Xuxue Guo, Changjie Wu, Chuncai Gu, Qiuhua Lai, Yuxin Fang, Junqi Huang, Zhizhang Wang, Aimin Li, Side Liu

Tumor-suppressive function of EZH2 is through inhibiting glutaminase

Cell Death Dis. 2021 Oct 20;12(11):975. doi: 10.1038/s41419-021-04212-7. (IF 6.304)

661. Dong-Zhuo Wei, Dan Li, Dan-Meng Zheng, Zhen-Ni An, Xue-Jiao Xing, Ding-Wen Jiang, Xi-Fan Mei, Chang Liu

Curcumin Conjugated Gold Nanoclusters as Perspective Therapeutics for Diabetic Cardiomyopathy

Front Chem. 2021 Oct 26;9:763892. doi: 10.3389/fchem.2021.763892. (IF 3.693)

662. Yanhong Shou, Lu Yang, Yongsheng Yang, Jinhua Xu

Inhibition of keratinocyte ferroptosis suppresses psoriatic inflammation

Cell Death Dis. 2021 Oct 27;12(11):1009. doi: 10.1038/s41419-021-04284-5. (IF 6.304)

663. Yunpeng Bai, Xiankun Liu, Qingliang Chen, Tongyun Chen, Nan Jiang, Zhigang Guo

Myricetin ameliorates ox-LDL-induced HUVECs apoptosis and inflammation via lncRNA GAS5 upregulating the expression of miR-29a-3p

Sci Rep. 2021 Oct 4;11(1):19637. doi: 10.1038/s41598-021-98916-7.

664. Hairong Tang, Yuru Liang, Jiayi Cheng, Kuiling Ding, Yang Wang

Bifunctional chiral selenium-containing 1,4-diarylazetidin-2-ones with potent antitumor activities by disrupting tubulin polymerization and inducing reactive oxygen species production

Eur J Med Chem. 2021 Oct 5;221:113531. doi: 10.1016/j.ejmech.2021.113531. (IF 5.572)

665. Si-Yang Li, Jin Shang, Xiao-Mei Mao, Rui Fan, Hui-Qi Li, Rui-Han Li, Dong-Yan Shen

Diosgenin exerts anti-tumor effects through inactivation of cAMP/PKA/CREB signaling pathway in colorectal cancer

Eur J Pharmacol. 2021 Oct 5;908:174370. doi: 10.1016/j.ejphar.2021.174370. (IF 3.263)

666. Ting-Ting Gong, Qian Guo, Xiao Li, Tie-Ning Zhang, Fang-Hua Liu, Xin-Hui He, Bei Lin, Qi-Jun Wu

Isothiocyanate Iberin inhibits cell proliferation and induces cell apoptosis in the progression of ovarian cancer by mediating ROS accumulation and GPX1 expression

Biomed Pharmacother. 2021 Oct;142:111533. doi: 10.1016/j.biopha.2021.111533. (IF 4.545)

667. Guanpeng Xu, Xi Li, Zhiyong Zhu, Huisheng Wang, Xizhuang Bai

Iron Overload Induces Apoptosis and Cytoprotective Autophagy Regulated by ROS Generation in Mc3t3-E1 Cells

Biol Trace Elem Res. 2021 Oct;199(10):3781-3792. doi: 10.1007/s12011-020-02508-x. (IF 2.639)

668. Cai-Ying Hu, Qian-Ying Zhang, Jie-Hui Chen, Bin Wen, Wei-Jian Hang, Kai Xu, Juan Chen, Ben-Hong He

Protective Effect of Salidroside on Mitochondrial Disturbances via Reducing Mitophagy and Preserving Mitochondrial Morphology in OGD-induced Neuronal Injury

Curr Med Sci. 2021 Oct;41(5):936-943. doi: 10.1007/s11596-021-2374-6. (IF 1.273)

669. Jie Tang, Mingrong Bei, Jia Zhu, Guangtao Xu, Deqing Chen, Xin Jin, Jianzhong Huang, Jingjian Dong, Lili Shi, Long Xu, Bo Hu

Acute cadmium exposure induces GSDME-mediated pyroptosis in triple-negative breast cancer cells through ROS generation and NLRP3 inflammasome pathway activation

Environ Toxicol Pharmacol. 2021 Oct;87:103686. doi: 10.1016/j.etap.2021.103686.

670. Yongfei He, Dalang Fang, Tianyi Liang, Hongbing Pang, Yingdan Nong, Libo Tang, Ziye Yang, Chunmiao Lu, Xiao Han, Shuqi Zhao, Shutian Mo, Yuhua Meng, Chuangye Han, Tao Peng

Atractylodin may induce ferroptosis of human hepatocellular carcinoma cells

Ann Transl Med. 2021 Oct;9(20):1535. doi: 10.21037/atm-21-4386. (IF 3.297)

671. Yang Zhang, Weifang Liu, Yanqi Zhong, Qi Li, Mengying Wu, Liu Yang, Xiaoxia Liu, Li Zou

Metformin Corrects Glucose Metabolism Reprogramming and NLRP3 Inflammasome-Induced Pyroptosis via Inhibiting the TLR4/NF- κ B/PFKFB3 Signaling in Trophoblasts: Implication for a Potential Therapy of P

Oxid Med Cell Longev. 2021 Nov 11;2021:1806344. doi: 10.1155/2021/1806344. (IF 5.076)

672. Shihua Deng, Dongming Wu, Li Li, Jin Li, Ying Xu

TBHQ attenuates ferroptosis against 5-fluorouracil-induced intestinal epithelial cell injury and intestinal mucositis via activation of Nrf2

Cell Mol Biol Lett. 2021 Nov 18;26(1):48. doi: 10.1186/s11658-021-00294-5. (IF 3.451)

673. Wenqi Liang, Chunli Zhao, Zhongrui Chen, Zijing Yang, Ke Liu, Shusheng Gong

Sirtuin-3 Protects Cochlear Hair Cells Against Noise-Induced Damage via the Superoxide Dismutase 2/Reactive Oxygen Species Signaling Pathway

Front Cell Dev Biol. 2021 Nov 18;9:766512. doi: 10.3389/fcell.2021.766512. (IF 5.201)

674. Yifan Wang, Wen Zhu, Dandan Lu, Chuzhao Zhang, Yue Wang

Tetrahydropalmatine attenuates MSU crystal-induced gouty arthritis by inhibiting ROS-mediated NLRP3 inflammasome activation

Int Immunopharmacol. 2021 Nov;100:108107. doi: 10.1016/j.intimp.2021.108107. (IF 3.943)

675. Jiaming Zhang, Xiaoxia Hao, Ruimin Chi, Jun Qi, Tao Xu

Moderate mechanical stress suppresses the IL-1β-induced chondrocyte apoptosis by regulating mitochondrial dynamics

J Cell Physiol. 2021 Nov;236(11):7504-7515. doi: 10.1002/jcp.30386. (IF 5.546)

676. Binda Sun, Shu He, Bao Liu, Gang Xu, Guoji E, Lan Feng, Licong Xu, Dewei Chen, Wenqi Zhao, Jian Chen, Yuqi Gao, Erlong Zhang

Stanniocalcin-1 Protected Astrocytes from Hypoxic Damage Through the AMPK Pathway

Neurochem Res. 2021 Nov;46(11):2948-2957. doi: 10.1007/s11064-021-03393-z. (IF 3.038)

677. Xiaojuan Zhu, Shichao Liu, Zhijiao Cao, Lei Yang, Fang Lu, Yulan Li, Lili Hu, Xiaoliang Bai

Higenamine mitigates interleukin-1β-induced human nucleus pulposus cell apoptosis by ROS-mediated PI3K/Akt signaling

Mol Cell Biochem. 2021 Nov;476(11):3889-3897. doi: 10.1007/s11010-021-04197-z. (IF 2.795)

678. Naijin Zhang, Ying Zhang, Boquan Wu, Shaojun Wu, Shilong You, Saien Lu, Jingwei Liu, Xinyue Huang, Jiaqi Xu, Liu Cao, Yingxian Sun

Deacetylation-dependent regulation of PARP1 by SIRT2 dictates ubiquitination of PARP1 in oxidative stress-induced vascular injury

Redox Biol. 2021 Nov;47:102141. doi: 10.1016/j.redox.2021.102141. (IF 9.986)

679. Yanting Pang, Daming Wu, Ying Ma, Yuna Cao, Qing Liu, Meng Tang, Yuepu Pu, Ting Zhang

Reactive oxygen species trigger NF-κB-mediated NLRP3 inflammasome activation involvement in low-dose CdTe QDs exposure-induced hepatotoxicity

Redox Biol. 2021 Nov;47:102157. doi: 10.1016/j.redox.2021.102157. (IF 9.986)

680. Ruonan Zhang, Ting Pan, Yu Xiang, Mingming Zhang, Han Xie, Zimao Liang, Bi Chen, Cong Xu, Jing Wang, Xingxing Huang, Qianru Zhu, Ziming Zhao, Quan Gao, Chengyong Wen, Wencheng Liu, Weirui Ma, Jiao Feng, Xueni Sun, Ting Duan, Elaine Lai-Han Leung, Tian Xie, Qibiao Wu, Xinbing Sui

Curcumenol triggered ferroptosis in lung cancer cells via lncRNA H19/miR-19b-3p/FTH1 axis

Bioact Mater. 2021 Nov 19:13:23-36. doi: 10.1016/j.bioactmat.2021.11.013.

681. Wen Ting Hao, Lu Huang, Wei Pan, Yi Le Ren

Antioxidant glutathione inhibits inflammation in synovial fibroblasts via PTEN/PI3K/AKT pathway: An in vitro study

Arch Rheumatol. 2021 Dec 24;37(2):212-222. doi: 10.46497/ArchRheumatol.2022.9109. (IF 0.731)

682. Qiao En, Huang Zeping, Wang Yuetang, Wang Xu, Wang Wei

Metformin alleviates the calcification of aortic valve interstitial cells through activating the PI3K/AKT pathway in an AMPK dependent way

Mol Med. 2021 Dec 11;27(1):156. doi: 10.1186/s10020-021-00416-x. (IF 4.096)

683. Yifan Hong, Yu Zhou, Lianju Shen, Yuexin Wei, Chunlan Long, Yan Fu, Huan Wu, Junke Wang, Yuhao Wu, Shengde Wu, Guanghui Wei

Exposure to DEHP induces testis toxicity and injury through the ROS/mTOR/NLRP3 signaling pathway in immature rats

Ecotoxicol Environ Saf. 2021 Dec 20;227:112889. doi: 10.1016/j.ecoenv.2021.112889.

684. Manman Cao, Xitong Huang, Fei Wang, Yiyue Zhang, Beihai Zhou, Huilun Chen, Rongfang Yuan, Shuai Ma, Huanhuan Geng, Dan Xu, Changchun Yan, Baoshan Xing

Transcriptomics and Metabolomics Revealed the Biological Response of Chlorella pyrenoidesa to Single and Repeated Exposures of AgNPs at Different Concentrations

Environ Sci Technol. 2021 Dec 7;55(23):15776-15787. doi: 10.1021/acs.est.1c04059. (IF 7.864)

685. Zhiwen Liu, Bin Yang

CTRP6(C1q/Tumor Necrosis Factor (TNF)-related protein-6) alleviated the sevoflurane induced injury of mice central nervous system by promoting the expression of p-Akt (phosphorylated Akt)

Bioengineered. 2021 Dec;12(1):5716-5726. doi: 10.1080/21655979.2021.1967838. (IF 2.205)

686. Xinyu Zhou, Zhonglong Wang, Bingchao Xu, Niu Ji, Pin Meng, Lei Gu, Ying Li

Long non-coding RNA NORAD protects against cerebral ischemia/reperfusion injury induced brain damage, cell apoptosis, oxidative stress and inflammation by regulating miR-30a-5p/YWHAG

Bioengineered. 2021 Dec;12(2):9174-9188. doi: 10.1080/21655979.2021.1995115. (IF 2.205)

687. Mingtai Gui, Lei Yao, Bo Lu, Jing Wang, Xunjie Zhou, Jianhua Li, Zhenhua Dong, Deyu Fu

Huoxue Qianyang Qutan recipe attenuates Ang II-induced cardiomyocyte hypertrophy by regulating reactive oxygen species production

Exp Ther Med. 2021 Dec;22(6):1446. doi: 10.3892/etm.2021.10881. (IF 1.785)

688. Lin Li, Zhenzhen Mu, Pengyue Liu, Ying Wang, Fan Yang, Xiuping Han

Mdivi-1 alleviates atopic dermatitis through the inhibition of NLRP3 inflammasome

Exp Dermatol. 2021 Dec;30(12):1734-1744. doi: 10.1111/exd.14412. (IF 3.368)

689. Lian Liu, Quan Cao, Wenwei Gao, Bing-Yu Li, Cheng Zeng, Zhongyuan Xia, Bo Zhao

Melatonin ameliorates cerebral ischemia-reperfusion injury in diabetic mice by enhancing autophagy via the SIRT1-BMAL1 pathway

FASEB J. 2021 Dec;35(12):e22040. doi: 10.1096/fj.202002718RR. (IF 4.966)

690. Gaofeng Zhang, Hai Wang, Qianxi Zhang, Zhengyu Zhao, Wenyang Zhu, Xiaohua Zuo

Bergenin alleviates H2 O2 -induced oxidative stress and apoptosis in nucleus pulposus cells: Involvement of the PPAR-γ/NF-κB pathway

Environ Toxicol. 2021 Dec;36(12):2541-2550. doi: 10.1002/tox.23368. (IF 3.118)

691. Kejun Zhou, Mengyi Xie, Shuli Yi, Yun Tang, Haojun Luo, Qiong Xiao, Jun Xiao, Yi Li

Dimethyl fumarate ameliorates endotoxin-induced acute kidney injury against macrophage oxidative stress

Ren Fail. 2021 Dec;43(1):1229-1239. doi: 10.1080/0886022X.2021.1963774.

692. Wen-Long Lei, Yuan-Yuan Li, Yi Hou, Chenli Liu, Wei-Ping Qian, Qing-Yuan Sun, Chun-Hui Zhang

Toxic effects of patulin on mouse oocytes and its possible mechanisms

Toxicology. 2021 Dec;464:153013. doi: 10.1016/j.tox.2021.153013. (IF 4.099)

693. Yan Peng, Li Zhang, Fanlin Zhou, Yangyang Wang, Xiong Zhang, Jianing Fan, Shijie Li, Xiaoju Li, Yu Li

Scavenging Reactive Oxygen Species Decreases Amyloid-β Levels via Activation of PI3K/Akt/GLUT1 Pathway in N2a/APP695swe Cells

J Alzheimers Dis. 2022;90(1):185-198. doi: 10.3233/JAD-220610. (IF 3.909)

694. Xinyue Hou, Jianxiang Shi, Jie Zhang, Zhigang Wang, Sen Zhang, Ruifeng Li, Wei Jiang, Tingting Huang, Jiancheng Guo, Wenjun Shang

Treatment of Acute Kidney Injury Using a Dual Enzyme Embedded Zeolitic Imidazolate Frameworks Cascade That Catalyzes In Vivo Reactive Oxygen Species Scavenging

Front Bioeng Biotechnol. 2022 Jan 4;9:800428. doi: 10.3389/fbioe.2021.800428.

695. Xiaoyi Wei, Yalin Zheng, Yanke Ai, Buman Li

Regulatory Effects of Astragaloside IV on Hyperglycemia-Induced Mitophagy in Schwann Cells

Evid Based Complement Alternat Med. 2022 Jan 11:2022:7864308. doi: 10.1155/2022/7864308.

696. Mi Gao, Chunxiao Liang, Wei Hong, Xiaoyuan Yu, Yumin Zhou, Ruiting Sun, Haiqing Li, Haichao Huang, Xuhong Gan, Ze Yuan, Jiahuan Zhang, Juan Chen, Qiudi Mo, Luyao Wang, Biting Lin, Bing Li, Pixin Ran

Biomass-related PM2.5 induces mitochondrial fragmentation and dysfunction in human airway epithelial cells

Environ Pollut. 2022 Jan 1;292(Pt B):118464. doi: 10.1016/j.envpol.2021.118464. (IF 6.792)

697. Fei Jia, Yu Liu, Xinyu Dou, Chuanchao Du, Tianli Mao, Xiaoguang Liu

Liensinine Inhibits Osteosarcoma Growth by ROS-Mediated Suppression of the JAK2/STAT3 Signaling Pathway

Oxid Med Cell Longev. 2022 Jan 25:2022:8245614. doi: 10.1155/2022/8245614. (IF 5.076)

698. Kailiang Zhang, Rong Bao, Fengyuan Huang, Kevin Yang, Yishu Ding, Lothar Lauterboeck, Masasuke Yoshida, Qinqiang Long, Qinglin Yang

ATP synthase inhibitory factor subunit 1 regulates islet β-cell function via repression of mitochondrial homeostasis

Lab Invest. 2022 Jan;102(1):69-79. doi: 10.1038/s41374-021-00670-x. (IF 4.197)

699. Yunguang Wang, Fangfang Feng, Wenfang He, Lifang Sun, Qiang He, Juan Jin

miR-188-3p abolishes germacrone-mediated podocyte protection in a mouse model of diabetic nephropathy in type I diabetes through triggering mitochondrial injury

Bioengineered. 2022 Jan;13(1):774-788. doi: 10.1080/21655979.2021.2012919. (IF 2.205)

700. Zhen-Yu Zhang, Yan-Lin An, Xiao-Shi Wang, Lan-Yue Cui, Shuo-Qi Li, Cheng-Bao Liu, Yu-Hong Zou, Fen Zhang, Rong-Chang Zeng

In vitro degradation, photo-dynamic and thermal antibacterial activities of Cu-bearing chlorophyllin-induced Ca-P coating on magnesium alloy AZ31

Bioact Mater. 2022 Feb 15:18:284-299. doi: 10.1016/j.bioactmat.2022.01.050.

701. Yuqin Mao, Jiqing Du, Xianghang Chen, Abdullah Al Mamun, Lin Cao, Yanhong Yang, Joana Mubwandarikwa, Muhammad Zaeem, Wanying Zhang, Yan Chen, Yusen Dai, Jian Xiao, Keyong Ye

Maltol Promotes Mitophagy and Inhibits Oxidative Stress via the Nrf2/PINK1/Parkin Pathway after Spinal Cord Injury

Oxid Med Cell Longev. 2022 Feb 1:2022:1337630. doi: 10.1155/2022/1337630. (IF 5.076)

702. Ping An, Xiao-Chun Zhao, Man-Jia Liu, Yu-Qing You, Jing-Ya Li

Gender-based differences in neuroprotective effects of hydrogen gas against intracerebral hemorrhage-induced depression

Neurochem Int. 2022 Feb:153:105276. doi: 10.1016/j.neuint.2022.105276. (IF 3.881)

703. Xin Han, Shaoqi Hu, Qiao Yang, Xianan Sang, Dongxin Tang, Gang Cao

Paeoniflorin ameliorates airway inflammation and immune response in ovalbumin induced asthmatic mice: From oxidative stress to autophagy

Phytomedicine. 2022 Feb:96:153835. doi: 10.1016/j.phymed.2021.153835. (IF 4.268)

704. Qi Zhou, Wei Wang, Jun Wu, Shang Qiu, Shuai Yuan, Pei-Liang Fu, Qi-Rong Qian, Yao-Zeng Xu

Ubiquitin-specific protease 3 attenuates interleukin-1β-mediated chondrocyte senescence by deacetylating forkhead box O-3 via sirtuin-3

Bioengineered. 2022 Feb;13(2):2017-2027. doi: 10.1080/21655979.2021.2012552. (IF 2.205)

705. Pei Xie, Li-Jun Yan, Hong-Ling Zhou, Hui-Hui Cao, Yuan-Ru Zheng, Zi-Bin Lu, Hua-Yi Yang, Jia-Mei Ma, Yu-Yao Chen, Chuying Huo, Chunyang Tian, Jun-Shan Liu, Lin-Zhong Yu

Emodin Protects Against Lipopolysaccharide-Induced Acute Lung Injury via the JNK/Nur77/c-Jun Signaling Pathway

Front Pharmacol. 2022 Mar 17:13:717271. doi: 10.3389/fphar.2022.717271. (IF 4.225)

706. Qin Wei, Xuan Xu, Long Chen, Tao Wang, Liang Xie, Fu-Chao Yu, Si-Fan Song, Zhi-Qiang Sheng, Jia-Yi Tong

Effects of chronic intermittent hypoxia on left cardiac function in young and aged mice

Am J Physiol Regul Integr Comp Physiol. 2022 Mar 1;322(3):R241-R252. doi: 10.1152/ajpregu.00256.2021.

707. Shasha Chen, Na Hu, Honglun Wang, Yongning Wu, Guoliang Li

Bioactivity-guided isolation of the major anthocyanin from Lycium ruthenicum Murr. fruit and its antioxidant activity and neuroprotective effects in vitro and in vivo

Food Funct. 2022 Mar 21;13(6):3247-3257. doi: 10.1039/d1fo04095b. (IF 4.171)

708. Jie Ding, Zhihao Zhang, Sui Li, Wei Wang, Tingyi Du, Qin Fang, Yan Wang, Dao Wen Wang

Mdivi-1 alleviates cardiac fibrosis post myocardial infarction at infarcted border zone, possibly via inhibition of Drp1-Activated mitochondrial fission and oxidative stress

Arch Biochem Biophys. 2022 Mar 30:718:109147. doi: 10.1016/j.abb.2022.109147. (IF 3.391)

709. Qi Pang, Peiwen Wang, Yajing Pan, Xingtong Dong, Ting Zhou, Xinyu Song, Aihua Zhang

Irisin protects against vascular calcification by activating autophagy and inhibiting NLRP3-mediated vascular smooth muscle cell pyroptosis in chronic kidney disease

Cell Death Dis. 2022 Mar 30;13(3):283. doi: 10.1038/s41419-022-04735-7. (IF 6.304)

710. Wenjing Li, Libing Yu, Bo Fu, Jian Chu, Chun Chen, Xijian Li, Jiahua Ma, Wei Tang

Protective effects of Polygonatum kingianum polysaccharides and aqueous extract on uranium-induced toxicity in human kidney (HK-2) cells

Int J Biol Macromol. 2022 Mar 31:202:68-79. doi: 10.1016/j.ijbiomac.2022.01.043. (IF 5.162)

711. Jiazheng Chen, Zichen Cui, Yi Wang, Linmao Lyu, Changgong Feng, Dianjie Feng, Yifan Cheng, Ziqing Li, Shui Sun

Cyclic Polypeptide D7 Protects Bone Marrow Mesenchymal Cells and Promotes Chondrogenesis during Osteonecrosis of the Femoral Head via Growth Differentiation Factor 15-Mediated Redox Signaling

Oxid Med Cell Longev. 2022 Mar 3:2022:3182368. doi: 10.1155/2022/3182368. (IF 5.076)

712. Hui Zhao, Jiannan Gong, Lifang Li, Shuyin Zhi, Guang Yang, Pingping Li, Ruina Li, Jianqiang Li

Vitamin E relieves chronic obstructive pulmonary disease by inhibiting COX2-mediated p-STAT3 nuclear translocation through the EGFR/MAPK signaling pathway

Lab Invest. 2022 Mar;102(3):272-280. doi: 10.1038/s41374-021-00652-z. (IF 4.197)

713. Huihong Jiang, Erjiang Tang, Ying Chen, Hailong Liu, Yun Zhao, Moubin Lin, Luwei He

Squalene synthase predicts poor prognosis in stage I-III colon adenocarcinoma and synergizes squalene epoxidase to promote tumor progression

Cancer Sci. 2022 Mar;113(3):971-985. doi: 10.1111/cas.15248. (IF 4.966)

714. Lirong Xu, Jiaxin Lin, Yutong Liu, Bingxuan Hua, Qianyun Cheng, Changpo Lin, Zuoqin Yan, Yaping Wang, Ning Sun, Ruizhe Qian, Chao Lu

CLOCK regulates Drp1 mRNA stability and mitochondrial homeostasis by interacting with PUF60

Cell Rep. 2022 Apr 12;39(2):110635. doi: 10.1016/j.celrep.2022.110635. (IF 8.109)

715. Qasim M Zeeshan, Shuang Qiu, Jia Gu, Abdul-Wahab Abbew, Zhengshuai Wu, Zhipeng Chen, Sai Xu, Shijian Ge

Unravelling multiple removal pathways of oseltamivir in wastewater by microalgae through experimentation and computation

J Hazard Mater. 2022 Apr 5:427:128139. doi: 10.1016/j.jhazmat.2021.128139. (IF 9.038)

716. Naijin Zhang, Ying Zhang, Wei Miao, Chuning Shi, Zihan Chen, Boquan Wu, Yuanming Zou, Qiushi Ma, Shilong You, Saien Lu, Xinyue Huang, Jingwei Liu, Jiaqi Xu, Liu Cao, Yingxian Sun

An unexpected role for BAG3 in regulating PARP1 ubiquitination in oxidative stress-related endothelial damage

Redox Biol. 2022 Apr:50:102238. doi: 10.1016/j.redox.2022.102238. (IF 9.986)

717. Liang Xia, Mingjie Gong, Yangfan Zou, Zeng Wang, Bin Wu, Shuyuan Zhang, Liwen Li, Kai Jin, Caixing Sun

A patinib Induces Ferroptosis of Glioma Cells through Modulation of the VEGFR2/Nrf2 Pathway

Oxid Med Cell Longev. 2022 May 11:2022:9925919. doi: 10.1155/2022/9925919. (IF 5.076)

718. Yaqiu Li, Zhu Dong, Sitong Liu, Fan Gao, Jinyu Zhang, Zhendong Peng, Lixin Wang, Xiaoyan Pan

Astaxanthin improves the development of the follicles and oocytes through alleviating oxidative stress induced by BPA in cultured follicles

Sci Rep. 2022 May 12;12(1):7853. doi: 10.1038/s41598-022-11566-1.

719. Wei Cheng, Yong Tang, Xiaobin Tong, Qin Zhou, Jingrong Xie, Jinlong Wang, Yun Han, Na Ta, Zhou Ye

USP53 activated by H3K27 acetylation regulates cell viability, apoptosis and metabolism in esophageal carcinoma via the AMPK signaling pathway

Carcinogenesis. 2022 May 19;43(4):349-359. doi: 10.1093/carcin/bgab123. (IF 4.603)

720. Xin Wang, Ming-Jing He, Xiao-Jie Chen, Yu-Ting Bai, Gang Zhou

Glaucocalyxin A impairs tumor growth via amplification of the ATF4/CHOP/CHAC1 cascade in human oral squamous cell carcinoma

J Ethnopharmacol. 2022 May 23:290:115100. doi: 10.1016/j.jep.2022.115100. (IF 3.69)

721. Lin Li, Yaowei Xuan, Biao Zhu, Xing Wang, Xiaoyu Tian, Lisheng Zhao, Yan Wang, Xiaoxia Jiang, Ning Wen

Protective Effects of C annabidiol on Chemotherapy-Induced Oral Mucositis via the Nrf2/Keap1/ARE Signaling Pathways

Oxid Med Cell Longev. 2022 May 25:2022:4619760. doi: 10.1155/2022/4619760. (IF 5.076)

722. Weibin Lin, Hao Yao, Jinqing Lai, Yile Zeng, Xieli Guo, Shu Lin, Weipeng Hu, Junyan Chen, Xiangrong Chen

Cycloastragenol Confers Cerebral Protection after Subarachnoid Hemorrhage by Suppressing Oxidative Insults and Neuroinflammation via the SIRT1 Signaling Pathway

Oxid Med Cell Longev. 2022 Jun 2:2022:3099409. doi: 10.1155/2022/3099409. (IF 5.076)

723. Haojie Chen, Guoke Tang, Jiangming Yu, Ronghua Yu

Neuroprotective Effects of Curcumin against Oxygen-Glucose Deprivation/Reoxygenation-Induced Injury in Cultured Primary Rat Astrocyte by Improving Mitochondrial Function and Regulating the ERK Signali

Evid Based Complement Alternat Med. 2022 Jul 12:2022:1731701. doi: 10.1155/2022/1731701.

724. Jian Yang, Jian Lu, Ni Yin, Jingyue Sun, Jianhong Pu, Jin Zang

miR-622 Counteracts the NUAK1-Induced Gastric Cancer Cell Proliferation and the Antioxidative Stress

Dis Markers. 2022 Jul 14:2022:9616764. doi: 10.1155/2022/9616764. (IF 2.738)

725. Yang Gai, Man-Yu Zhang, Peng-Yuan Ji, Rong-Jing You, Zhao-Jia Ge, Wei Shen, Qing-Yuan Sun, Shen Yin

Melatonin improves meiosis maturation against diazinon exposure in mouse oocytes

Life Sci. 2022 Jul 15:301:120611. doi: 10.1016/j.lfs.2022.120611. (IF 3.647)

726. Guo-Qiang Luo, Shuang Bai, Yan Hu, Hu Chen, Zhong-Jun Yan, Ling-Ling Fan

CD147 Protein Expression and Temozolomide Resistance in Glioma Cells: An Ex vivo and In vivo Study

Cell Mol Biol (Noisy-le-grand). 2022 Jul 31;68(7):160-164. doi: 10.14715/cmb/2022.68.7.26.

727. Mengqi Wang, Jingyu Ren, Zhanpeng Liu, Shubin Li, Liya Su, Biao Wang, Daoning Han, Gang Liu

Beneficial Effect of Selenium Doped Carbon Quantum Dots Supplementation on the in vitro Development Competence of Ovine Oocytes

Int J Nanomedicine. 2022 Jul 4:17:2907-2924. doi: 10.2147/IJN.S360000.

728. Yuqian An, Yi Li, Yujun Hou, Shichao Huang, Gang Pei

Alzheimer's Amyloid- β Accelerates Cell Senescence and Suppresses the SIRT1/NRF2 Pathway in Human Microglial Cells

Oxid Med Cell Longev. 2022 Aug 17:2022:3086010. doi: 10.1155/2022/3086010. (IF 5.076)

729. Yixing Gao, Lan Feng, Luping Zhang, Jianhui Geng, Erlong Zhang

ATF4/MYC Regulates MTHFD2 to Promote NSCLC Progression by Mediating Redox Homeostasis

Dis Markers. 2022 Aug 22:2022:7527996. doi: 10.1155/2022/7527996. (IF 2.738)

730. Liping Wang, Tiantian Ji, Ye Yuan, Haoyu Fu, Yang Wang, Shaobo Tian, Jia Hu, Lin Wang, Zheng Wang

High-fructose corn syrup promotes proinflammatory Macrophage activation via ROS-mediated NF-κB signaling and exacerbates colitis in mice

Int Immunopharmacol. 2022 Aug:109:108814. doi: 10.1016/j.intimp.2022.108814. (IF 3.943)

731. Rui Jin, Qianqian Gao, Chunyu Yin, Mengjia Zou, Keyu Lu, Wei Liu, Yuting Zhu, Mingshun Zhang, Rui Cheng

The CD146-HIF-1α axis regulates epithelial cell migration and alveolar maturation in a mouse model of bronchopulmonary dysplasia

Lab Invest. 2022 Aug;102(8):794-804. doi: 10.1038/s41374-022-00773-z. (IF 4.197)

732. Ting Wu, Hongqiao Zhu, Miaomiao Zhang, Yuling Sun, Yongjing Yang, Lili Gu, Jing Zhang, Dan Mu, Congye Wu, Zhigang Hu, Longwei Jiang, Shaochang Jia, Ying Zhang, Lingfeng He, Fei-Yan Pan, Zhigang Guo

FEN1 inhibitor synergizes with low-dose camptothecin to induce increased cell killing via the mitochondria mediated apoptotic pathway

Gene Ther. 2022 Aug;29(7-8):407-417. doi: 10.1038/s41434-020-00215-9. (IF 4.128)

733. Yuandong Shao, Lei Sun, Guihe Yang, Wenchao Wang, Xiaoyang Liu, Ting Du, Feifei Chen, Xingzhi Jing, Xingang Cui

Icariin protects vertebral endplate chondrocytes against apoptosis and degeneration via activating Nrf-2/HO-1 pathway

Front Pharmacol. 2022 Sep 13:13:937502. doi: 10.3389/fphar.2022.937502. (IF 4.225)

734. Yan Lin, Dongxu Wang, Hong Zhao, Dongyue Li, Xinning Li, Lianjie Lin

Pou3f1 mediates the effect of Nfatc3 on ulcerative colitis-associated colorectal cancer by regulating inflammation

Cell Mol Biol Lett. 2022 Sep 5;27(1):75. doi: 10.1186/s11658-022-00374-0. (IF 3.451)

735. Liqin Qi, Ruonan Gao, Zhou Chen, Donghai Lin, Zhiqing Liu, Linxi Wang, Lijing Lin, Xiaoying Liu, Xiaohong Liu, Libin Liu

Liraglutide reduces oxidative stress and improves energy metabolism in methylglyoxal-induced SH-SY5Y cells

Neurotoxicology. 2022 Sep:92:166-179. doi: 10.1016/j.neuro.2022.08.007. (IF 3.105)

736. Libin Chen, Wang Xue, Jing Cao, Shengmin Zhang, Yiqing Zeng, Ling Ma, Xuechen Qian, Qing Wen, Yurong Hong, Zhan Shi, Youfeng Xu

TiSe2-mediated sonodynamic and checkpoint blockade combined immunotherapy in hypoxic pancreatic cancer

J Nanobiotechnology. 2022 Oct 15;20(1):453. doi: 10.1186/s12951-022-01659-4.

737. Tao Yang, Qingguo Zhao, Meijun Hu, Simin Pan, Linying Zhang, Ruoxi Zhu, Bowen Zhou, Xuanhe Feng, Zhenhua Gao, Zhao Zhu, Yu Zhang, Liang Hu, Fei Liu, Zhaochen Shan

Sphingosine-1-Phosphate Alleviates Irradiation Induced Salivary Gland Hypofunction through Preserving Endothelial Cells and Resident Macrophages

Antioxidants (Basel). 2022 Oct 18;11(10):2050. doi: 10.3390/antiox11102050.

738. Fanshuo Yin, Ying Zhang, Xin Zhang, Meichen Zhang, Zaihong Zhang, Yunyi Yin, Haili Xu, Yanmei Yang, Yanhui Gao

The ROS/NF-κB/HK2 axis is involved in the arsenic-induced Warburg effect in human L-02 hepatocytes

Int J Environ Health Res. 2022 Oct 20:1-16. doi: 10.1080/09603123.2022.2134559.

739. Mingjun Han, Jie Lin, Yi Yang, Yumei Ding, Wenjun Ge, Haoran Fan, Ce Wang, Wen Xie

Xinshuaining preparation protects H9c2 cells from H2O2-induced oxidative damage through the PI3K/Akt/Nrf-2 signaling pathway

Clin Exp Hypertens. 2022 Oct 20:1-9. doi: 10.1080/10641963.2022.2131806. (IF 1.789)

740. Rui Li, Mengying Ke, Mingming Qi, Zhenru Han, Yuhao Cao, Zhendong Deng, Jinjun Qian, Ye Yang, Chunyan Gu

G6PD promotes cell proliferation and dexamethasone resistance in multiple myeloma via increasing anti-oxidant production and activating Wnt/β-catenin pathway

Exp Hematol Oncol. 2022 Oct 21;11(1):77. doi: 10.1186/s40164-022-00326-6.

741. Xueyan Wang, Chengwei Duan, Yu Li, Hongjian Lu, Kongwei Guo, Xin Ge, Tianpeng Chen, Yanxing Shang, Hongbin Liu, Dongmei Zhang

Sodium butyrate reduces overnutrition-induced microglial activation and hypothalamic inflammation

Int Immunopharmacol. 2022 Oct:111:109083. doi: 10.1016/j.intimp.2022.109083. (IF 3.943)

742. Lihua Li, Kunpeng Wang, Rongjun Jia, Jing Xie, Liman Ma, Zhiqing Hao, Weiwei Zhang, Jinggang Mo, Fu Ren

Ferroportin-dependent ferroptosis induced by ellagic acid retards liver fibrosis by impairing the SNARE complexes formation

Redox Biol. 2022 Oct:56:102435. doi: 10.1016/j.redox.2022.102435. (IF 9.986)

743. Shuhui Liu, Zhangshan Gao, Wanqiu He, Yuting Wu, Jiwen Liu, Shuo Zhang, Liping Yan, Shengyong Mao, Xizhi Shi, Wentao Fan, Suquan Song

The gut microbiota metabolite glycochenodeoxycholate activates TFR-ACSL4-mediated ferroptosis to promote the development of environmental toxin-linked MAFLD

Free Radic Biol Med. 2022 Nov 20;193(Pt 1):213-226. doi: 10.1016/j.freeradbiomed.2022.10.270.

744. Sheng-Qing Gao, Jia-Jun Shi, Xue-Wang, Shu-Hao Miao, Tao Li, Chao-Chao Gao, Yan-Ling Han, Jia-Yin Qiu, Yun-Song Zhuang, Meng-Liang Zhou

Endothelial NOX4 aggravates eNOS uncoupling by decreasing dihydrofolate reductase after subarachnoid hemorrhage

Free Radic Biol Med. 2022 Nov 20;193(Pt 2):499-510. doi: 10.1016/j.freeradbiomed.2022.10.318.

745. Qian Feng, Lin Wang, Yu Chen, Jie Teng, Mengmei Li, Zhongzhen Cai, Xiaoguo Niu, Glen Rein, Qiaoli Yang, Xiaoqian Shao, Chao Zhang, Xuemei Bai

Effects of different music on HEK293T cell growth and mitochondrial functions

Explore (NY). 2022 Nov-Dec;18(6):670-675. doi: 10.1016/j.explore.2022.01.002.

746. Shaofan Hu, Jing Feng, Meng Wang, Reziyamu Wufuer, Keli Liu, Zhengwen Zhang, Yiguo Zhang

Nrf1 is an indispensable redox-determining factor for mitochondrial homeostasis by integrating multi-hierarchical regulatory networks

Redox Biol. 2022 Nov:57:102470. doi: 10.1016/j.redox.2022.102470. (IF 9.986)

747. Yanjie Guo, Ruofei Li, Xiaoqian Dang

S100A10 regulates tumor necrosis factor alpha-induced apoptosis in chondrocytes via the reactive oxygen species/nuclear factor-kappa B pathway

Biotechnol Appl Biochem. 2022 Dec;69(6):2284-2295. doi: 10.1002/bab.2285.

748. Yang Meng, Lei Qiu, Xinyi Zeng, Xiaoyan Hu, Yaguang Zhang, Xiaowen Wan, Xiaobing Mao, Jian Wu, Yongfeng Xu, Qunli Xiong, Zhixin Chen, Bo Zhang, Junhong Han

Targeting CRL4 suppresses chemoresistant ovarian cancer growth by inducing mitophagy

Signal Transduct Target Ther. 2022 Dec 9;7(1):388. doi: 10.1038/s41392-022-01253-y.

749. Pu Zhang, Meirong Zang, Zhenzhen Sang, Yunxia Wei, Yan Yan, Xiaohua Bian, Shimin Dong

Vitamin C alleviates LPS-induced myocardial injury by inhibiting pyroptosis via the ROS-AKT/mTOR signalling pathway

BMC Cardiovasc Disord. 2022 Dec 22;22(1):561. doi: 10.1186/s12872-022-03014-9.

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