重组人SENP2(小泛素修饰特异性蛋白酶2)

特别提示：包括重组人SENP2(小泛素修饰特异性蛋白酶2)在内，本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！

产品名称：重组人SENP2(小泛素修饰特异性蛋白酶2)
英文名称：Recombinant Human Sentrin-specific protease 2
产品货号：JN0971
产品规格：10μg|50μg|500μg|1mg

本品由我们的大肠杆菌表达系统制备而成，目的基因编码的Asp363-Leu589在N端带有His和SUMO标签。

SENP2质量控制：＞95%(还原性SDS-PAGE)

SENP2制剂：液体

SENP2保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。

关于SENP2：
SENP2 is an enzyme that belongs to the peptidase C48 family. SENP2 is a protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. SUMO1 is a small ubiquitin-like protein that can be covalently conjugated to other proteins. It has been implicated as a down-regulator of CTNNB1 levels and may therefore be a modulator of the Wnt pathway.

除了重组人SENP2(小泛素修饰特异性蛋白酶2),，我公司还供应以下相关产品：



名称：重组人NT3(神经营养素3)(含前导肽)
货号：JN0223
规格：10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备，目的基因编码的Asn19-Thr257表达纯化而来。

NT-3(with pro peptide)质量控制：＞95%(还原性SDS-PAGE)。

NT-3(with pro peptide)制剂：冻干品

NT-3(with pro peptide)保存：
冻干蛋白可在-20℃长期保存，室温也可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天。
复溶后建议分装冻存在-20℃，可保存3个月，应避免反复冻融。

NT-3(with pro peptide)复溶：
1、试剂开盖前请先离心。
2、复溶浓度应大于100 μg/ml.
3、冻干蛋白溶于ddH2O中
4、复溶后根据使用量分装保存，避免反复冻融。

关于NT-3(with pro peptide)：
Pro-Neurotrophin-3 (pro-NT3) is the precursor form of Neurotrophin-3. Pro-NT3 interacts preferentially with the pan-neurotrophin receptor p75 (p75NTR) and vps10p domain-containing receptor sortilin and induces neuronal apoptosis, whereas mature NT3 selectively binds with high affinity to the TrkB kinase receptor and promotes the survival, growth and differentiation of neurons. As proneurotrophins and mature neurotrophins elicit opposite biological effects, Pro-BDNF cleavage in the neuronal system is regulated in a specific and cell-context dependent manner.